Tumor grade estımatıon of clear cell and papıllary renal cell carcınomas usıng contrast-enhanced MDCT and FSE T2 weıghted MR ımagıng: radıology-pathology correlatıon

2021 ◽  
Author(s):  
Ahmet Mesrur Halefoglu ◽  
Ayse Aysim Ozagari
Keyword(s):  
Mr Imaging ◽  
Renal Cell ◽  
Clear Cell ◽  
Tumor Grade ◽  
Renal Cell Carcinomas ◽  
Grade Estimation ◽  
Contrast Enhanced

scholarly journals Tumor grade of clear cell renal cell carcinoma assessed by contrast-enhanced computed tomography

SpringerPlus ◽  
2014 ◽  
Vol 3 (1) ◽  
Author(s):  
Kousei Ishigami ◽  
Leandro V. Leite ◽  
Marius G. Pakalniskis ◽  
Daniel K. Lee ◽  
Danniele G. Holanda ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Tumor Grade ◽  
Cell Renal Cell Carcinoma ◽  
Contrast Enhanced ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

Diffusion-weighted imaging versus contrast-enhanced MR imaging for the differentiation of renal oncocytomas and chromophobe renal cell carcinomas

2017 ◽  
Vol 27 (12) ◽  
pp. 4913-4922 ◽  
Author(s):  
Yan Zhong ◽  
Haiyi Wang ◽  
Yanguang Shen ◽  
Aitao Guo ◽  
Jia Wang ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Renal Cell ◽  
Diffusion Weighted Imaging ◽  
Renal Cell Carcinomas ◽  
Diffusion Weighted ◽  
Contrast Enhanced ◽  
Renal Oncocytomas

scholarly journals Comparison of computed tomography (CT), magnetic resonance imaging (MRI) and contrast-enhanced ultrasound (CEUS) in the evaluation of unclear renal lesions

2020 ◽  
Vol 192 (11) ◽  
pp. 1053-1059 ◽  
Author(s):  
Constantin Arndt Marschner ◽  
Johannes Ruebenthaler ◽  
Vincent Schwarze ◽  
Giovanna Negrão de Figueiredo ◽  
Lan Zhang ◽  
...  
Keyword(s):  
Renal Cell ◽  
Clear Cell ◽  
Contrast Enhanced Ultrasound ◽  
Resonance Imaging ◽  
Benign Lesions ◽  
Renal Cell Carcinomas ◽  
Renal Lesions ◽  
Contrast Enhanced ◽  
Malignant Lesions ◽  
Magnetic Resonance Imaging Mri

Purpose To compare the sensitivity and specificity of contrast-enhanced ultrasound (CEUS), computed tomography (CT) and magnetic resonance imaging (MRI) in the evaluation of unclear renal lesions to the histopathological outcome. Materials and methods A total of 255 patients with a single unclear renal mass with initial imaging studies between 2005 and 2015 were included. Patient ages ranged from 18 to 86 with (mean age 62 years; SD ± 13). CEUS (255 patients), CT (88 out of 255 patients; 34.5 %) and MRI (36 out of 255 patients; 14.1 %) were used for determining malignancy or benignancy and initial findings were correlated with the histopathological outcome. Results CEUS showed a sensitivity of 99.1 % (95 % confidence interval (CI): 96.7 %, 99.9 %), a specificity of 80.5 % (95 % CI: 65.1 %, 91.2 %), a positive predictive value (PPV) of 96.4 % (95 % CI: 93.0 %, 98.4 %) and a negative predictive value (NPV) of 94.3 % (95 % CI: 80.8 %, 99.3 %). CT showed a sensitivity of 97.1 % (95 % CI: 89.9 %, 99.6 %), a specificity of 47.4 % (95 % CI: 24.4 %, 71.1 %), a PPV of 87.0 % (95 % CI: 77.4 %, 93.6 %) and a NPV of 81.8 % (95 % CI: 48.2 %, 97.7 %). MRI showed a sensitivity of 96.4 % (95 % CI: 81.7 %, 99.9 %), a specificity of 75.0 % (95 % CI: 34.9 %, 96.8 %), a PPV of 93.1 % (95 % CI: 77.2 %, 99.2 %) and a NPV of 85.7 % (95 % CI: 42.1 %, 99.6 %). Out of the 212 malignant lesions a total of 130 clear cell renal carcinomas, 59 papillary renal cell carcinomas, 7 chromophobe renal cell carcinomas, 4 combined clear cell and papillary renal cell carcinomas and 12 other malignant lesions, e. g. metastases, were diagnosed. Out of the 43 benign lesions a total 10 angiomyolipomas, 3 oncocytomas, 8 benign renal cysts and 22 other benign lesions, e. g. renal adenomas were diagnosed. Using CEUS, 10 lesions were falsely identified as malignant or benign, whereas 8 lesions were false positive and 2 lesions false negative. Conclusion CEUS is an useful method which can be additionally used to clinically differentiate between malignant and benign renal lesions. CEUS shows a comparable sensitivity, specificity, PPV and NPV to CT and MRI. In daily clinical routine, patients with contraindications for other imaging modalities can particularly benefit using this method. Key Points:  Citation Format

scholarly journals PD14-07 DIFFERENTIATION BETWEEN CLEAR CELL RENAL CELL CARCINOMAS AND ONCOCYTOMAS USING TEXTURE ANALYSIS OF CT IMAGES

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Vinay Duddalwar ◽  
Xuejun Zhang ◽  
Darryl Hwang ◽  
Steven Cen ◽  
Felix Yap ◽  
...  
Keyword(s):  
Texture Analysis ◽  
Renal Cell ◽  
Clear Cell ◽  
Ct Images ◽  
Renal Cell Carcinomas

The Diagnostic Accuracy of Percutaneous Renal Needle Core Biopsy and Its Potential Impact on the Clinical Management of Renal Cortical Neoplasms

2014 ◽  
Vol 138 (12) ◽  
pp. 1673-1679 ◽  
Author(s):  
Lan L. Gellert ◽  
Rohit Mehra ◽  
Ying-Bei Chen ◽  
Anuradha Gopalan ◽  
Samson W. Fine ◽  
...  
Keyword(s):  
Clinical Management ◽  
Renal Cell ◽  
Core Biopsy ◽  
Clear Cell ◽  
Renal Tumors ◽  
Low Grade ◽  
Renal Cell Carcinomas ◽  
Biopsy Diagnosis ◽  
Potential Impact ◽  
Renal Cortical Neoplasms

Context While biopsies are now increasingly being performed for the diagnosis of renal cortical neoplasms, the influence of the rendered pathological diagnoses on the clinical management is only rarely documented. Objectives To report our experience with consecutively performed renal biopsies and the potential impact of the diagnosis on subsequent clinical management. Design Material from needle biopsies performed consecutively at our institution between 2006 and 2011 was reviewed. The influence of the reported pathology results on the clinical management was determined from patient follow-up medical record review. Results In total, 218 percutaneous biopsies for renal masses were performed during this period. Among them, 181 (83%) yielded neoplastic tissue, including 81 clear cell renal cell carcinomas, 29 low-grade oncocytic neoplasms, 7 papillary renal cell carcinomas, 5 clear cell papillary renal cell carcinomas, 5 angiomyolipomas, and 14 urothelial carcinomas. Fourteen additional cases (6%) contained lesional material from clinically known nonneoplastic processes, for a total diagnostic yield of 89%. Twenty-three (11%) were nonrepresentative of lesional tissue. In 10 of these, repeat biopsies or resections established the diagnosis of renal tumors. Biopsy diagnosis was confirmed in 29 of 30 cases (97%) on subsequent nephrectomy. Following the biopsy diagnosis, there were significant differences in the clinical management; overall, 79% of clear cell renal cell carcinomas received therapeutic interventions, and 17% were put on active surveillance. In contrast, 77% of the benign or low-grade lesions were put on active surveillance. Conclusions Accurate and specific diagnosis can be rendered on renal core biopsy in most renal tumors, and the biopsy diagnosis can have a definitive role in their clinical management.

Strength of molecular cytogenetic analyses for adjusting the diagnosis of renal cell carcinomas: a study of four cases with complete or hybrid morphology of clear cell carcinomas

2010 ◽  
Vol 203 (1) ◽  
pp. 91
Author(s):  
Laurence Bianchini ◽  
Juliette Haudebourg ◽  
Benjamin Hoch ◽  
Thibault Fabas ◽  
Fanny Burel-Vandenbos ◽  
...  
Keyword(s):  
Renal Cell ◽  
Clear Cell ◽  
Renal Cell Carcinomas ◽  
Molecular Cytogenetic ◽  
Cytogenetic Analyses

Parametric imaging of clear cell and papillary renal cell carcinoma using contrast-enhanced ultrasound (CEUS)

2016 ◽  
Vol 63 (2) ◽  
pp. 89-97 ◽  
Author(s):  
J. Rübenthaler ◽  
R. Reimann ◽  
P. Hristova ◽  
M. Staehler ◽  
M. Reiser ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Clear Cell ◽  
Papillary Renal Cell Carcinoma ◽  
Parametric Imaging ◽  
Contrast Enhanced Ultrasound ◽  
Contrast Enhanced
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