Finding susceptible and protective interaction patterns in large-scale genetic association study

2017 ◽  
Vol 11 (3) ◽  
pp. 541-554 ◽  
Author(s):  
Yuan Li ◽  
Yuhai Zhao ◽  
Guoren Wang ◽  
Xiaofeng Zhu ◽  
Xiang Zhang ◽  
...  
Keyword(s):  
Association Study ◽  
Genetic Association ◽  
Genetic Association Study ◽  
Large Scale ◽  
Interaction Patterns

A large-scale genetic association study of ossification of the posterior longitudinal ligament of the spine

2006 ◽  
Vol 119 (6) ◽  
pp. 611-616 ◽  
Author(s):  
Taizo Horikoshi ◽  
Koichi Maeda ◽  
Yoshiharu Kawaguchi ◽  
Kazuhiro Chiba ◽  
Kanji Mori ◽  
...  
Keyword(s):  
Association Study ◽  
Genetic Association ◽  
Genetic Association Study ◽  
Large Scale ◽  
Posterior Longitudinal Ligament

scholarly journals A Large-scale genetic association study of esophageal adenocarcinoma risk

2010 ◽  
Vol 31 (7) ◽  
pp. 1259-1263 ◽  
Author(s):  
Chen-yu Liu ◽  
Michael C. Wu ◽  
Feng Chen ◽  
Monica Ter-Minassian ◽  
Kofi Asomaning ◽  
...  
Keyword(s):  
Association Study ◽  
Genetic Association ◽  
Esophageal Adenocarcinoma ◽  
Genetic Association Study ◽  
Large Scale

scholarly journals A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease

2011 ◽  
Vol 32 (3) ◽  
pp. 548.e9-548.e18 ◽  
Author(s):  
Rejko Krüger ◽  
Manu Sharma ◽  
Olaf Riess ◽  
Thomas Gasser ◽  
Christine Van Broeckhoven ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Association Study ◽  
Genetic Association ◽  
Genetic Association Study ◽  
Large Scale

PLCG2 rs72824905 Variant Reduces the Risk of Alzheimer’s Disease and Multiple Sclerosis

2021 ◽  
pp. 1-7
Author(s):  
Fan Chen ◽  
Yan Zhang ◽  
Longcai Wang ◽  
Tao Wang ◽  
Zhifa Han ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Association Study ◽  
Genetic Association ◽  
Genetic Association Study ◽  
Large Scale

We aimed to evaluate the association of PLCG2 rs72824905 variant with Alzheimer’s disease (AD) and multiple sclerosis (MS) using large-scale genetic association study datasets. We selected 50,024 AD cases and 467,330 controls, and 32,367 MS cases and 36,012 controls. We found moderate heterogeneity of rs72824905 in different studies. We found significant association between rs72824905 G allele and reduced AD risk (OR = 0.66, 95% CI 0.59–0.74, p = 5.91E-14). Importantly, rs72824905 G allele could also significantly reduce the risk of MS with OR = 0.94, p = 3.63E-05. Hence, the effects of rs72824905 on AD and MS are consistent.

scholarly journals A Large-Scale Genetic Association Study Confirms IL12B and Leads to the Identification of IL23R as Psoriasis-Risk Genes

2007 ◽  
Vol 80 (2) ◽  
pp. 273-290 ◽  
Author(s):  
Michele Cargill ◽  
Steven J. Schrodi ◽  
Monica Chang ◽  
Veronica E. Garcia ◽  
Rhonda Brandon ◽  
...  
Keyword(s):  
Association Study ◽  
Genetic Association ◽  
Genetic Association Study ◽  
Large Scale ◽  
Risk Genes
Sign in / Sign up

Export Citation Format

Share Document