Vitamin B12 levels in patients with retinal vein occlusion and their relation with clinical outcome: a retrospective study

2022 ◽  
Author(s):  
Francesco Paciullo ◽  
Paola Santina Menduno ◽  
Davide Tucci ◽  
Anna Caricato ◽  
Carlo Cagini ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Clinical Outcome ◽  
Vitamin B12 ◽  
Retinal Vein Occlusion ◽  
Vein Occlusion

Vitamin B12 and Folate as Risk Factors for Retinal Vein Occlusion: A Meta-Analysis

2021 ◽  
Author(s):  
Dimitrios Kazantzis ◽  
Panagiotis Theodossiadis ◽  
Christos Kroupis ◽  
George Theodossiadis ◽  
Irini Chatziralli
Keyword(s):  
Vitamin B12 ◽  
Retinal Vein Occlusion ◽  
Meta Analysis ◽  
Serum Vitamin ◽  
Mean Difference ◽  
Serum Folate ◽  
Case Control Studies ◽  
Vein Occlusion ◽  
Pubmed Database ◽  
Significant Difference

Abstract Purpose To evaluate the association between serum vitamin B12/folate and retinal vein occlusion (RVO). Methods A comprehensive search of the PubMed database was performed, which identified 271 abstracts to be screened. Ten studies met our inclusion criteria and a meta-analysis of these comparative case-control studies was performed on the mean ± standard deviation serum vitamin B12 and folate levels, without language restrictions. Nine studies with 720 patients with RVO and 613 controls were included in the meta-analysis for vitamin B12, and 10 studies with 784 patients with RVO and 677 controls in the meta-analysis for folate. Results There was no statistically significant difference between patients with RVO and controls in serum vitamin B12 levels (mean difference: − 40.25 pg/mL, p = 0.28), either central RVO (mean difference: − 18.24 pg/mL, p = 0.71) or branch RVO (mean difference: − 23.56 pg/mL, p = 0.48). On the contrary, the plasma folate level was significantly lower in RVO patients than in controls (mean difference: − 1.34 ng/mL, p = 0.001), as well as in patients with CRVO compared to controls (mean difference: − 1.48 ng/mL, p = 0.006), but not in BRVO patients (mean difference: − 0.72 ng/mL, p = 0.11). Conclusions RVO is associated with low serum folate levels, but not with serum vitamin B12 levels.

scholarly journals Intravitreal ranibizumab for macular oedema secondary to retinal vein occlusion: a retrospective study of 34 eyes

2010 ◽  
Vol 90 (4) ◽  
pp. 357-361 ◽  
Author(s):  
Nathalie Puche ◽  
Agnès Glacet ◽  
Gérard Mimoun ◽  
Alain Zourdani ◽  
Gabriel Coscas ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Retinal Vein Occlusion ◽  
Macular Oedema ◽  
Intravitreal Ranibizumab ◽  
Vein Occlusion

Intravitreal dexamethasone for central retinal vein occlusion with low visual acuity: a retrospective study

2013 ◽  
Vol 97 (6) ◽  
pp. 796-797 ◽  
Author(s):  
Christiana Dinah ◽  
Kapka Nenova ◽  
Sreekumari Pushpoth ◽  
Ibraheem El-Ghrably ◽  
Deepali Varma ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Retrospective Study ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Vein Occlusion ◽  
Intravitreal Dexamethasone ◽  
Central Retinal Vein

Lipid profile and serum folate, vitamin B12 and homocysteine levels in patients with retinal vein occlusion

2021 ◽  
Author(s):  
José Javier Napal Lecumberri ◽  
Paula González Bores ◽  
Alicia Cuesta Marín ◽  
Francisco Alejandro Caballero Avendaño ◽  
Jose Manuel Olmos Martínez ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Lipid Profile ◽  
Retinal Vein Occlusion ◽  
Serum Folate ◽  
Vein Occlusion

A retrospective study of the influence of the vitreomacular interface on macular oedema secondary to retinal vein occlusion

2017 ◽  
Vol 101 (10) ◽  
pp. 1340-1345 ◽  
Author(s):  
Rishi P Singh ◽  
Karishma A Habbu ◽  
Rumneek Bedi ◽  
Fabiana Q Silva ◽  
Justis P Ehlers ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Retinal Vein Occlusion ◽  
Macular Oedema ◽  
Vein Occlusion ◽  
Vitreomacular Interface

scholarly journals The Systemic and Ocular Risk Factors for Retinal Vein Occlusion: A Retrospective Study

2021 ◽  
Author(s):  
Jiacheng Ye ◽  
Min Zhou ◽  
Congyao Wang ◽  
Pengxia Wan
Keyword(s):  
Risk Factors ◽  
Visual Acuity ◽  
Retrospective Study ◽  
Endothelial Dysfunction ◽  
Retinal Vein Occlusion ◽  
Central Retinal Vein Occlusion ◽  
Retinal Thickness ◽  
Low Vision ◽  
Vein Occlusion ◽  
Central Retinal Vein

Abstract BACKGROUND: We sought to evaluate the systemic and ocular risk factors for severity on visual acuity and central retinal thickness in macular edema secondary to retinal vein occlusion (RVO-ME). METHODS: This retrospective study included 46 RVO-ME patients in The First Affiliated Hospital of Sun Yat-sen University from January 2015 to November 2019. Systemic examinations include blood pressure, blood glucose, blood lipids, vascular endothelial function, and carotid artery color ultrasound. Ocular examinations include the best-corrected visual acuity (BCVA) and the central retinal thickness (CRT). The integrity of the outer retina was evaluated as well. According to the baseline BCVA and CRT levels, the patients were divided into high vision group and low vision group, high CRT group, and low CRT group. Multivariate logistic regression analyses were performed to analyze the risk factors on baseline BCVA and CRT.RESULTS: We enrolled 19 eyes of CRVO (central retinal vein occlusion) and 27 eyes of BRVO (branch retinal vein occlusion). We identified 31 (67.4%) as high CRT and 23 (50.0%) as poor VA of 46 patients on admission. There were 15 cases of BRVO in the high CRT group (48.4%) and 12 cases in the low CRT group (80.0%). The type of disease (BRVO/CRVO) was an independent factor of baseline CRT (P=0.017). Endothelial dysfunction correlates with baseline BCVA independently (P=0.038). Ellipsoidal zone (EZ) destruction was found in 19 cases (82.6%) in the low vision group and 6 cases (26.1%) in the high vision group. EZ integrity correlates with baseline BCVA independently (P=0.017). CONCLUSION: The central retinal vein occlusion (CRVO) has markedly higher CRT than branch retinal vein occlusion (BRVO). Endothelial dysfunction and disrupted ellipsoidal zone were significantly associated with poor baseline VA on admission.

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