Bariatric Surgery Prior to Total Joint Arthroplasty, Does it Decrease the Risk of Obesity Related Perioperative Complications?

2018 ◽  
Vol 20 (2) ◽  
Author(s):  
A. I. Stavrakis ◽  
A. Khoshbin ◽  
A. S. McLawhorn ◽  
M. L. Parks
2019 ◽  
Vol 15 (2) ◽  
pp. 190-200 ◽  
Author(s):  
Alex Gu ◽  
Jordan S. Cohen ◽  
Michael-Alexander Malahias ◽  
Danny Lee ◽  
Peter K. Sculco ◽  
...  

2018 ◽  
Vol 49 (3) ◽  
pp. 297-306 ◽  
Author(s):  
Jessica M. Hooper ◽  
Ajit J. Deshmukh ◽  
Ran Schwarzkopf

2017 ◽  
Vol 28 (5) ◽  
pp. 1395-1401 ◽  
Author(s):  
Ran Schwarzkopf ◽  
Jessica A. Lavery ◽  
Jessica Hooper ◽  
Manish Parikh ◽  
Heather T. Gold

2017 ◽  
Vol 23 (8) ◽  
pp. 967-972 ◽  
Author(s):  
Christopher Wanderling ◽  
Jeffrey Liles ◽  
Elissa Finkler ◽  
Peter Carlsgaard ◽  
William Hopkinson ◽  
...  

Total joint arthroplasty (TJA) of the hip or knee (THA, TKA) has become an increasingly common procedure. While TJA is a successful treatment for individuals experiencing degenerative joint diseases, it is well known that one of the most common perioperative complications of TJA is deep venous thrombosis (DVT). To profile tissue factor (TF), microparticle-tissue factor (MP-TF), thrombin-activatable fibrinolysis inhibitor (TAFI), and fibrinogen levels in patients undergoing TJA to determine potential preexisting Hemostatic dysregulation. De-identified blood samples were obtained from patients undergoing TJA 1 day pre- and 1 day postprocedure. Plasma samples were analyzed using enzyme-linked immunosorbent assay kits for fibrinogen, TAFI, TF, and MP-TF; fibrinogen levels were also assessed using a clot-based activity assay. In comparison with healthy controls, there were significant increases of fibrinogen and MP-TF levels, while there were significant decreases in TF and TAFI levels in the preoperative and postoperative patients. Comparing the pre versus postoperative patients, no significant differences were found; interestingly, however, surgical intervention exacerbated the changes found in the preoperative samples compared to the controls. The results of this study confirm that patients undergoing TJA have preexisting alterations in the fibrinolytic system. Surgical intervention tended to exacerbate these changes. The alterations observed in this study may provide insight as to why TJA is associated with higher rates of DVT and thromboembolism.


2016 ◽  
Vol 12 (7) ◽  
pp. S29-S30
Author(s):  
Emanuel Nearing ◽  
Tyler Santos ◽  
Mark Topolski ◽  
Andrew Borgert ◽  
Kara Kallies ◽  
...  

2017 ◽  
Vol 13 (3) ◽  
pp. 457-462 ◽  
Author(s):  
Emanuel E. Nearing ◽  
Tyler M. Santos ◽  
Mark S. Topolski ◽  
Andrew J. Borgert ◽  
Kara J. Kallies ◽  
...  

Arthroplasty ◽  
2022 ◽  
Vol 4 (1) ◽  
Author(s):  
Michael W. Seward ◽  
Antonia F. Chen

AbstractThe preoperative period prior to elective total joint arthroplasty (TJA) is a critical time for lifestyle interventions since a scheduled surgery may help motivate patients to lose weight. Weight loss may reduce complications associated with obesity following TJA and enable patients with severe obesity (body mass index [BMI] > 40 kg/m2) to become eligible for TJA, as many institutions use a 40 kg/m2 cut-off for offering surgery. A comprehensive review was conducted to (1) provide background on complications associated with obesity following TJA, (2) synthesize prior research on the success rate of patients losing weight after being denied TJA for severe obesity, (3) discuss bariatric surgery before TJA, and (4) propose mobile health telemedicine weight loss interventions as potential weight loss methods for patients preoperatively.It is well established that obesity increases complications associated with TJA. In total knee arthroplasty (TKA), obesity increases operative time, length of stay, and hospitalization costs as well as the risk of deep infection, revision, and component malpositioning. Obesity may have an even larger impact on complications associated with total hip arthroplasty (THA), including wound complications and deep infection. Obesity also increases the risk of hip dislocation, aseptic loosening, and venous thromboembolism after THA.Synthesis of the only two studies (n = 417), to our knowledge, that followed patients denied TJA for severe obesity demonstrated that only 7% successfully reduced their BMI below 40 kg/m2 via lifestyle modifications and ultimately underwent TJA. Unfortunately, bariatric surgery may only increase certain post-TKA complications including death, pneumonia, and implant failure, and there is limited research on preoperative weight loss via lifestyle modification. A review of short-term mobile health weight loss interventions that combined personalized counseling with self-monitoring via a smartphone app found about 5 kg of weight loss over 3-6 months. Patients with severe obesity have more weight to lose and may have additional motivation to do so before TJA, so weight loss results may differ by patient population. Research is needed to determine whether preoperative mobile health interventions can help patients become eligible for TJA and produce clinically significant weight loss sufficient to improve postoperative outcomes.


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