scholarly journals Erratum to: Bortezomib interferes with adhesion of B cell precursor acute lymphoblastic leukemia cells through SPARC up-regulation in human bone marrow mesenchymal stromal/stem cells

2017 ◽  
Vol 105 (5) ◽  
pp. 704-705 ◽  
Author(s):  
Masaki Iwasa ◽  
Yasuo Miura ◽  
Aya Fujishiro ◽  
Sumie Fujii ◽  
Noriko Sugino ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Acute Lymphoblastic Leukemia ◽  
B Cell ◽  
Lymphoblastic Leukemia ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Leukemia Cells ◽  
Cell Precursor ◽  
Stromal Stem Cells

An effective, direct immunomagnetic procedure for purging acute lymphoblastic leukemia cells from human bone marrow

1995 ◽  
Vol 1 (1) ◽  
pp. 32-37 ◽  
Author(s):  
Meng Y Wang ◽  
Øystein Fodstad ◽  
Wolf-Dieter Ludwig ◽  
Mats Bengtsson ◽  
Thomas Totterman ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Acute Lymphoblastic Leukemia ◽  
Lymphoblastic Leukemia ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Leukemia Cells

Inhibition of DNA-PK enhances chemosensitivity of B-cell precursor acute lymphoblastic leukemia cells to doxorubicin

2017 ◽  
Vol 94 ◽  
pp. 1077-1093 ◽  
Author(s):  
Fatemeh Alikarami ◽  
Majid Safa ◽  
Mohammad Faranoush ◽  
Parisa Hayat ◽  
Ahmad Kazemi
Keyword(s):  
Acute Lymphoblastic Leukemia ◽  
B Cell ◽  
Lymphoblastic Leukemia ◽  
Leukemia Cells ◽  
Cell Precursor

Resveratrol inhibits adipocyte differentiation and cellular senescence of human bone marrow stromal stem cells

Bone ◽  
2020 ◽  
Vol 133 ◽  
pp. 115252 ◽  
Author(s):  
Dalia Ali ◽  
Li Chen ◽  
Justyna M. Kowal ◽  
Meshail Okla ◽  
Muthurangan Manikandan ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Cellular Senescence ◽  
Adipocyte Differentiation ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Stromal Stem Cells

Amplification of RUNX1 gene in two new cases of childhood B-cell precursor acute lymphoblastic leukemia: A case report

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e21000-e21000
Author(s):  
A. Fauzdar ◽  
A. Mahajan ◽  
D. Jain ◽  
M. Mishra ◽  
V. Raina
Keyword(s):  
Bone Marrow ◽  
Acute Lymphoblastic Leukemia ◽  
B Cell ◽  
Lymphoblastic Leukemia ◽  
Chromosome 21 ◽  
Fish Analysis ◽  
Cell Precursor ◽  
Childhood All ◽  
Mll Gene ◽  
Runx1 Gene

e21000 Background: Chromosome abnormalities of leukemia cells have important prognostic significance in childhood acute lymphoblastic leukemia (ALL). B-cell precursor acute lymphoblastic leukemia (BCP-ALL) ETV6/RUNX1 (alias TEL/AML1) is most frequent i.e. 15 - 35% in the children with 2 - 18 age group. We report two new cases with Pre B- cell ALL without ETV6/RUNX1 rearrangement, showing amplification of AML1 gene detected by FISH analysis. Methods: Bone marrow samples were analyzed for chromosomal abnormalities with conventional G-banding techniques and interphase fluorescence in situ hybridization (FISH) using probes to detect BCR/ABL t(9;22)(q34-q11) fusion, cryptic TEL/AML1 t(12:21)(p13-q22) and MLL rearrangement for del 11q23. Results: In first case a 3-year girl with four copies of AML (RUNX1) gene were observed in 95% of the cell with normal two copies of TEL (ETV6) gene in both interphase and metaphase FISH. We observed BCR-ABL negative translocation and no MLL gene rearrangement in all the interphase cells after doing FISH. We got a normal 46XX karyotype from bone marrow with conventional cytogenetics (CC) in the same patient. In second case, a 4-year male we observed four copies of AML and two copies of TEL gene in more than 80% of cells. In this patient, we got BCR-ABL negative translocation and three copies of MLL gene without any rearrangement through FISH. We got normal 46XY karyotype in the same patient through CC. Conclusions: In both the patients, we observed hyperdiploidy detected with four copies of RUNX1 gene showing tetrasomy of chromosome 21 detected with metaphase FISH analysis whereas G-banding shows normal diploidy. Bone marrow karyotype in combination with molecular cytogenetic techniques like FISH should be done for improvement in sensitivity and accurate cytogenetic analysis in childhood ALL patients for proper identification of prognostic group for optimum treatment. This is one of the few reported studies worldwide for amplification of RUNX1 gene from Indian subcontinent in childhood BCP-ALL. No significant financial relationships to disclose.

Profiling of membrane proteins of human bone marrow stromal stem cells during ex vivo osteoblast differentiation using SILAC-based quantitative proteomics

Bone ◽  
2012 ◽  
Vol 50 ◽  
pp. S77
Author(s):  
H. Christiansen ◽  
K.H. Larsen⁎ ◽  
J.S. Burns ◽  
I. Kratchmarova ◽  
B.M. Abdallah ◽  
...  
Keyword(s):  
Stem Cells ◽  
Bone Marrow ◽  
Membrane Proteins ◽  
Quantitative Proteomics ◽  
Osteoblast Differentiation ◽  
Ex Vivo ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Stromal Stem Cells
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