Doet minimal brain dysfunction zijn herintrede in de DSM-5 als neurobiologische ontwikkelingsstoornis?

2020 ◽  
Vol 41 (4) ◽  
pp. 402-404
Author(s):  
N. N. J. Rommelse
1967 ◽  
Author(s):  
Douglas A. Stevens ◽  
James A. Boydstun ◽  
Roscoe A. Dykman ◽  
John E. Peters ◽  
David W. Sinton

1976 ◽  
Vol 69 (3) ◽  
pp. 325
Author(s):  
Felix F. de la Cruz

2019 ◽  
Vol 3 (s1) ◽  
pp. 37-37
Author(s):  
Jo Ellen Wilson ◽  
Sarasota Mihalko ◽  
Stephan Heckers ◽  
Pratik P. Pandharipande ◽  
Timothy D. Girard ◽  
...  

OBJECTIVES/SPECIFIC AIMS: Delirium, a form of acute brain dysfunction, characterized by changes in attention and alertness, is a known independent predictor of mortality in the Intensive Care Unit (ICU). We sought to understand whether catatonia, a more recently recognized form of acute brain dysfunction, is associated with increased 30-day mortality in critically ill older adults. METHODS/STUDY POPULATION: We prospectively enrolled critically ill patients at a single institution who were on a ventilator or in shock and evaluated them daily for delirium using the Confusion Assessment for the ICU and for catatonia using the Bush Francis Catatonia Rating Scale. Coma, was defined as a Richmond Agitation Scale score of −4 or −5. We used the Cox Proportional Hazards model predicting 30-day mortality after adjusting for delirium, coma and catatonia status. RESULTS/ANTICIPATED RESULTS: We enrolled 335 medical, surgical or trauma critically ill patients with 1103 matched delirium and catatonia assessments. Median age was 58 years (IQR: 48 - 67). Main indications for admission to the ICU included: airway disease or protection (32%; N=100) or sepsis and/or shock (25%; N=79. In the unadjusted analysis, regardless of the presence of catatonia, non-delirious individuals have the highest median survival times, while delirious patients have the lowest median survival time. Comparing the absence and presence of catatonia, the presence of catatonia worsens survival (Figure 1). In a time-dependent Cox model, comparing non-delirious individuals, holding catatonia status constant, delirious individuals have 1.72 times the hazards of death (IQR: 1.321, 2.231) while those with coma have 5.48 times the hazards of death (IQR: 4.298, 6.984). For DSM-5 catatonia scores, a 1-unit increase in the score is associated with 1.18 times the hazards of in-hospital mortality. Comparing two individuals with the same delirium status, an individual with a DSM-5 catatonia score of 0 (no catatonia) will have 1.178 times the hazard of death (IQR: 1.086, 1.278), while an individual with a score of 3 catatonia items (catatonia) present will have 1.63 times the hazard of death. DISCUSSION/SIGNIFICANCE OF IMPACT: Non-delirious individuals have the highest median survival times, while those who are comatose have the lowest median survival times after a critical illness, holding catatonia status constant. Comparing the absence and presence of catatonia, the presence of catatonia seems to worsen survival. Those individual who are both comatose and catatonic have the lowest median survival time.


1979 ◽  
Vol 12 (7) ◽  
pp. 450-455 ◽  
Author(s):  
Robert J. Lerer ◽  
Jeanne Artner ◽  
M Pamela Lerer

2021 ◽  
Vol 4 (1) ◽  

The most common feet pathologies of children are valgus and valgus planus deformities, which are congenital or connected with neurological dysfunctions (Minimal Brain Dysfunction). In adults, and mostly in women, we observe: 1. Köhler’s disease among girls wearing improper shoes. 2. Insufficiency and pain of the front part of feet connected with limited toes flexion, 3. Valgus deformity of the big toes (hallux valgus), 4. “Ankle Joint Pain Syndrome” (AJPS)-sometimes also “Knee Joint Pain Syndrome” (KJPS)-described by us only in USA, India and Czech Republic. In presented article, we describe this special type of foot insufficiency- “instability of ankle or knee, or both joints”-on left leg in drivers and right leg in passengers in countries with right-hand traffic. More frequent it concerns the foot and article focus on this problem.


2019 ◽  
Vol 3 (3) ◽  
pp. 1-7
Author(s):  
Karski Tomasz

Every fourth woman and every sixth man in the world coming to the Orthopedic or Neurology Departments complain of spinal pains - information from WHO, D ecade of Bones and Joints 2000 - 2010 (Lars Lidgren). According to our observations there are six main causes of such spinal disorders: 1. Lumbar Hyperlordosis causes by flexion contracture of hips and in result anterior tilt of the pelvis. Common in persons with Minimal Brain Dysfunction (MBD). Pain syndromes appear after overstress in some kinds of jobs or in sport. 2. Lumbar or thoracic - lumbar left convex “C” scoliosis in 2nd/A etiopathological group (epg) or ”S” scoliosis in 2nd/B epg in Lublin classification. Pain syndromes appear after overstr ess in some kinds of jobs or in sport. 3. Stiffness of the spine as clinical sign of “I” scoliosis in 3rd epg group in Lublin classification. 4. Spondylolisth esis or spodylolisis in sacral - lumbar or lumbar spine. 5. Urgent “nucleus prolapsed” (in German “Hexen Sch uss”). 6. Extremely cooling of the back part of trunk during work or intensive walking in low temperature. In many of patients in clinical examination we see positive Laseguae test. Sometimes we see weakness of extensors of the feet or paresis of the foot. Our observations confirm that not surgery, but physiotherapy can be beneficial to the patients with spinal problems.


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