The short- and long-term impact of the Ramadan fast on body weight and cardiometabolic factors: a pilot study in an ethnic obese adolescent cohort.

2013 ◽  
Vol 81 (S1) ◽  
pp. 96-96
Author(s):  
Nalini N.E. Radhakishun ◽  
Charlotte Blokhuis ◽  
Mariska van Vliet ◽  
Jos H. Beijnen ◽  
Ines A. von Rosenstiel
2020 ◽  
Vol 79 (3) ◽  
pp. 357-366
Author(s):  
Helen Truby ◽  
Christie Bennett ◽  
Catia Martins

This review seeks to synthesise our knowledge about changes in hunger and satiety that occur during diet-induced weight loss and during weight loss maintenance, with a particular focus on youth with obesity. Mechanisms of appetite responses to weight loss rely heavily on the adult literature. Physiological mechanisms that control appetite and satiety via the gut–brain axis have been elucidated but we have an incomplete picture of changes in gut hormones and peptides in youth with obesity. In adolescents, the role of the brain in long-term sensing of body composition and modifying appetite and satiety changes is easily over-ridden by hedonic influences for the reward of highly palatable sweet foods and encourages over-consumption. Accordingly, reward cues and hyper-responsiveness to palatable foods lead to a pattern of food choices. Different reward systems are necessary that are substantial enough to reward the continued individual effort required to sustain new behaviours, that need to be adopted to support a reduced body weight. Periods of growth and development during childhood provide windows of opportunity for interventions to influence body weight trajectory but long-term studies are lacking. More emphasis needs to be placed on anticipatory guidance on how to manage powerful hedonic influences of food choice, essential to cope with living in our obesogenic environment and managing hunger which comes with the stronger desire to eat after weight has been lost.


2015 ◽  
Vol 22 (4) ◽  
pp. 389-394 ◽  
Author(s):  
Arrigo F. G. Cicero ◽  
Maddalena Benelli ◽  
Marco Brancaleoni ◽  
Giuseppe Dainelli ◽  
Desiré Merlini ◽  
...  

2000 ◽  
Vol 19 (8) ◽  
pp. 434-439 ◽  
Author(s):  
C E M van Gelderen ◽  
J A Bijlsma ◽  
W van Dokkum ◽  
T J F Savelkoull

Because from earlier experiments in rats and a pilot study in humans a no effect level of glycyrrhizic acid could not be established, a second experiment was performed in healthy volunteers. The experiment was performed in females only, because the effects were most marked in females in the pilot study. Doses of 0, 1, 2 and 4 mg glycyrrhizic acid/kg body weight were administered orally for 8 weeks to 39 healthy female volunteers aged 19-40 years. The experimentlasted 12 weeks including an adaptation and a “wash-out” period.Ano-effectlevel of2 mg/kgis proposed from the results ofthis study, from which an acceptable daily intake (ADI) of 0.2 mg/kg body weight can be extrapolated with a safety factor of 10. This means consumption of 12 mg glycyrrhizic acid/day for a person with a body weight of 60 kg. This would be equal to 6 g licorice a day, assuming that licorice contains 0.2% of glycyrrhizic acid. The proposed ADI is below the limit advised by the Dutch Nutrition Council of 200 mg glycyrrhizic acid/day. This reflects the relatively mild acute toxicity of glycyrrhizic acid, which is also emphasised by the “generally recognised as safe” (GRAS) status of glycyrrhizic acid in the USA in 1983. However, the long-term effects of a mild chronic intoxication (causing, for example, a mild hypertension), although not immediately lethal, justify special attention to the amount of glycyrrhizic acid used daily.


2018 ◽  
Vol 12 (12) ◽  
pp. e0006758 ◽  
Author(s):  
Luc E. Coffeng ◽  
Susana Vaz Nery ◽  
Darren J. Gray ◽  
Roel Bakker ◽  
Sake J. de Vlas ◽  
...  

2021 ◽  
Author(s):  
Tamanna Tiwari ◽  
Lori Cofano ◽  
Christina Wood ◽  
Julie Frantsve-Hawley

Author(s):  
Steven J. Ericson

This chapter discusses the Matsukata deflation and its impact on domestic agriculture and industry and on foreign trade. Regardless of whether scholars hold negative or positive views of the Matsukata reform, they have tended to overstate both the short- and long-term impact of the deflation-induced depression as well as the role of the reform itself in bringing about the “Matsukata deflation” in the first place. If Matsukata had strictly followed an orthodox program of financial stabilization, the depression would likely have been as severe as most accounts claim. But his deviations from orthodoxy—boosting government spending, promoting exports of commodities from the rural sector, and the like—helped to buffer the economy and abridge the downturn. In short, the chapter asserts that one needs to qualify the commonly held view that the Matsukata reform was “a devastating experience for millions of people.”


2018 ◽  
Vol 29 (1-4) ◽  
pp. 120-172
Author(s):  
Helen Duffy

This article reflects on the proliferation of responses to the so-called phenomenon of “foreign terrorist fighters,” and the profound human rights challenges they give rise to. It considers national, regional and international developments, many spurred by an activist Security Council, through which expanded powers have been assumed and rights restricted by reference to the need to respond to ftf threats. A series of uncomfortable relationships emerge from this analysis. They include for example tensions: between the evolving and still relatively superficial understanding of the nature and source of uncertain threats and contributing factors on the one hand, and the onerous and far-reaching nature of responses directed against them on the other; between the expansive use of coercive measures including criminal law, and basic constraining principles of criminal law upon which its legitimacy and power depends, such as individual culpability, harm principle and remoteness; or between the original purposes of most ftf measures and their impact in practice, on the operation of humanitarian law, on humanitarian workers and human rights defenders, and on the rule of law. Exceptional ftf measures continue to spread their reach and creep into other areas of security and organised crime. The article highlights the need to consider the short and long term impact, on the full range of rights of many, of the array of administrative, criminal and other measures being passed into law and implemented in practice across the globe in the name of responding to the ill-defined phenomenon of “ftfs”.


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