scholarly journals Estimation of CD4+ T Cell Count Parameters in HIV/AIDS Patients Based on Real-time Nonlinear Receding Horizon Control

2018 ◽  
Vol 16 (4) ◽  
pp. 1805-1813
Author(s):  
Fei Sun ◽  
Kamran Turkoglu
2019 ◽  
Vol 6 (7) ◽  
Author(s):  
Win Le Shwe Sin Ei ◽  
Kyi Pyar Soe ◽  
Adelene Hilbig ◽  
Jillian Murray ◽  
David Heiden

Abstract A retrospective review of diagnosis of cytomegalovirus retinitis (CMVR) before and after introduction of routine immediate eye examination among AIDS patients in Myanmar with an absolute CD4 T-cell count <100 cells/μL demonstrated an increased detection of CMVR from 1.1% (14/1233) to 10.7% (65/608), an improvement of ~10-fold. Diagnosis of CMVR was achieved a mean of 2 days after clinic enrollment.


2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Shimelis Assefa ◽  
Berhanu Erko ◽  
Girmay Medhin ◽  
Zelalem Assefa ◽  
Techalew Shimelis

2019 ◽  
Vol 56 (4) ◽  
pp. 344-350
Author(s):  
Claudinei Mesquita da SILVA ◽  
Leyde Daiane de PEDER ◽  
Mateus Vailant THOMAZELLA ◽  
Jorge Juarez Vieira TEIXEIRA ◽  
Dennis Armando BERTOLINI

ABSTRACT BACKGROUND: Hepatitis B and C virus (HBV and HCV) are the two most common infections among human immunodeficiency virus (HIV)-infected patients. OBJECTIVE: To identify the frequency of HIV subtypes and HCV genotypes in HIV-coinfected patients. METHODS: A cross-sectional and retrospective study was carried out into two reference centers in Southern Brazil between January 1, 2002 and June 30, 2016. The Abbott Real Time HCV Genotype II system was used for routine diagnostics to determine the HCV genotype based on dual-target real-time PCR. Proviral HIV-1 RNA was extracted from serum samples and fragments of the pol gene were generated by PCR. The HIV-1 PT and RT gene sequences were submitted to Maximum Likelihood Phylogenetic analysis by collecting reference sequences from the HIV-1 group M subtype of the Los Alamos database. RESULTS: During the study period, 3340 patients with HIV were diagnosed at both referral centers, of which 4.97% (166/3340) had HBV and/or HCV coinfection. Seroprevalence of HIV-HBV, HIV-HCV and HIV-HBV-HCV was 37.4%, 58.4%, and 4.2%, respectively. HIV-HCV-coinfected patients had a lower median nadir CD4+ T-cell count when compared to HIV-HBV-coinfected patients (P=0.01). Among those coinfected with HCV, HCV-1 (HCV-1) and HCV-3 (HCV-3) genotypes were the most prevalent, being detected in 73.8% and 21.4%, respectively. Among the HCV-1 coinfected patients, 79.3% and 20.1% had subtypes 1a and 1b, respectively. HIV subtype B was the most prevalent in HIV-coinfected patients. There was no significant difference regarding nadir CD4+ T-cell count and HIV viral load when compared to coinfected with HCV-1 with HCV-3, as well as those co-infected with HCV-1a with HCV-1b. CONCLUSION: In the present study, a higher frequency of subtype B of HIV and HCV-1 were found in HIV-coinfected patients. Further larger-scale and long-term studies are needed to better understand the effect of HCV genotypes in HIV-infected patients.


2014 ◽  
Vol 13 (3) ◽  
pp. 186
Author(s):  
Sumintarti Sumintarti ◽  
Andi Rasdiana S

Oral candidiasis is one of clinical manifestations in aquired immune deficiency syndrome (AIDS) patients. This conditionis a common opportunistic infection of the oral cavity caused by an overgrowth of Candida spesies. The clinical types oforal candidiasis are erythematous or atropic, pseudomembranous, hyperplastic or chronic, and angular cheilitis. AIDS isgroup of symptoms that resulting from infection of human immunodeficiency virus (HIV). This case is associated with thedecreasing of CD4 count. The aimof this study was to know the types of oral candidiasis on AIDS patients at Dr WahidinSudirohusodo Hospital. This observational studywith a cross-sectional design examined 30 patients with AIDS whosuffered fromoral candidiasis, to determine its type after the diagnosis had confirmed by culture test. Their CD4 cellcount taken fromtheir medical records. The result showed that Pseudomembranous candidiasis were found to be higher(76.7%), that was followed by angular cheilitis (23.3%), hyperplastic (16.7%), and erythematous (6.7%). They wereshowed showed CD4 T cell count <200 cells/mm3 (63.3%). From this study, it was concluded that pseudomembranous candidiasis is the most common type and showed that CD4 T cell count <200cells/mmfrom the AIDS patients.


2009 ◽  
Vol 49 (10) ◽  
pp. 1619-1620
Author(s):  
Susanna Naggie ◽  
Tsung Hseih ◽  
Jennifer Reckleff ◽  
Joe Castellano ◽  
Charles B. Hicks

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