Local curative effect of MRI-guided radiofrequency ablation on small hepatocellular carcinoma

Tumor Biology ◽  
2014 ◽  
Vol 36 (3) ◽  
pp. 2105-2110 ◽  
Author(s):  
Zheng-Yu Lin ◽  
Qian-Qian Song ◽  
Jin Chen ◽  
Ren-Jun Wan ◽  
Hui Zheng ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Small Hepatocellular Carcinoma ◽  
Curative Effect ◽  
Mri Guided

scholarly journals A Comparison between Three-Dimensional Visualization Guided Hepatectomy and Ultrasonography Guided Radiofrequency Ablation in the Treatment of Small Hepatocellular Carcinoma within the Milan Criteria

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Tian-pei Guan ◽  
Chi-hua Fang ◽  
Jian Yang ◽  
Nan Xiang ◽  
Qing-shan Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Cox Regression ◽  
Alternative Therapy ◽  
Three Dimensional ◽  
Primary Treatment ◽  
Small Hepatocellular Carcinoma ◽  
Visualization System ◽  
Tumor Number ◽  
Serum Alpha Fetoprotein

Background. Treatment selection for small hepatocellular carcinoma (sHCC) is controversial. We aimed to compare the outcomes of medical imaging three-dimensional visualization system (MI-3DVS) guided surgical resection (SR) and ultrasonography guided radiofrequency ablation (RFA) for sHCC.Methods. In total, 194 patients who underwent SR or RFA in our hospital between January 2006 and May 2010 were retrospectively enrolled. Overall survival (OS), recurrence-free survival (RFS), and postoperative complications were compared. Cox regression was used to estimate the benefits of MI-3DVS-guided SR on OS and RFS.Results. Ninety-two patients underwent SR and 102 underwent RFA. The SR group experienced more complications (41.3% versus 19.6%) and longer hospital stay (18.04±7.11versus13.06±5.59) (bothp<0.05). The 1-, 2-, 3-, 4-, and 5-year OS was 96.7%, 95.7%, 93.5%, 83.5%, and 61.1% in the SR group and 95.0%, 88.1%, 72.7%, 56.9%, and 39.5% in the RFA group. Corresponding RFS was 95.7%, 94.6%, 84.7%, 59.8%, and 40.2% in SR group and 91.2%, 80.3%, 60.5%, 32.3%, and 22.3% in RFA group. The 5-year OS and RFS were higher in SR group (bothp<0.001). Interestingly, there was no significance in OS and RFS among subgroups aged >60 years. Independent predictors of OS and RFS, respectively, were intervention (HR, 2.769 and 1.933), tumor number (HR, 5.128 and 3.903), and serum alpha-fetoprotein (AFP) (HR, 1.871 and 1.474) (allp<0.05).Conclusions. MI-3DVS based hepatectomy should be considered primary treatment while RFA can be treated as alternative therapy for older patients. Intervention, tumor number, and AFP are independent predictors for both survival and recurrence.

scholarly journals Diffuse intrahepatic recurrence after percutaneous radiofrequency ablation for solitary and small hepatocellular carcinoma

2009 ◽  
Vol 3 (3) ◽  
pp. 509-515 ◽  
Author(s):  
Yoshiyuki Mori ◽  
Hideyuki Tamai ◽  
Naoki Shingaki ◽  
Kosaku Moribata ◽  
Tatsuya Shiraki ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Intrahepatic Recurrence ◽  
Small Hepatocellular Carcinoma ◽  
Percutaneous Radiofrequency Ablation

Clinical utility of radiofrequency ablation following transarterial injection of miriplatin-iodized oil suspension in small hepatocellular carcinoma

2016 ◽  
Vol 34 (9) ◽  
pp. 640-646 ◽  
Author(s):  
Ken Nakajima ◽  
Takashi Yamanaka ◽  
Atsuhiro Nakatsuka ◽  
Takaki Haruyuki ◽  
Masashi Fujimori ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Radiofrequency Ablation ◽  
Clinical Utility ◽  
Small Hepatocellular Carcinoma ◽  
Iodized Oil
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