Complete response of gastrointestinal stromal tumor liver metastases to regorafenib

2014 ◽  
Vol 4 (3) ◽  
pp. 167-171 ◽  
Author(s):  
Hiromitsu Kitayama ◽  
Michiaki Hirayama ◽  
Junko Sugiyama ◽  
Tomohiro Kondo ◽  
Yumiko Oyamada ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Gastrointestinal Stromal Tumor ◽  
Complete Response ◽  
Stromal Tumor

scholarly journals Preoperative therapy with sunitinib malate in a patient with a gastrointestinal stromal tumor and liver metastases

Medicine ◽  
2019 ◽  
Vol 98 (51) ◽  
pp. e14222 ◽  
Author(s):  
Zhi-Qiang Wang ◽  
Zheng-Qi Wen ◽  
Jun Yang ◽  
Hong-bin Zhang ◽  
Zhi-yong Kou ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Gastrointestinal Stromal Tumor ◽  
Stromal Tumor ◽  
Preoperative Therapy ◽  
Sunitinib Malate

Fulminant Hepatic Failure Caused by Diffuse Liver Metastases following Gastrointestinal Stromal Tumor Resection

2009 ◽  
Vol 2 ◽  
pp. CGast.S3221
Author(s):  
Abdel-Rauf Zeina ◽  
Alicia Nachtigal ◽  
Eugene Vlodavsky ◽  
Jochanan E. Naschitz
Keyword(s):  
Liver Metastases ◽  
Gastrointestinal Stromal Tumor ◽  
Fulminant Hepatic Failure ◽  
Hepatic Failure ◽  
Tumor Resection ◽  
Stromal Tumor ◽  
Prognostic Features ◽  
Elevated Liver Enzymes ◽  
Complete Tumor

Metastatic tumors to the liver resulting in fulminant hepatic failure are a rare occurrence and have not been previously described in patients with gastrointestinal stromal tumor (GIST). A 70 year-old man was referred to hospital with postprandial discomfort. On examination a 19.5 cm large epithelioid GIST of the stomach was diagnosed. The mass exhibited unfavorable prognostic features: mitotic index 18/50 high-power fields, large primary tumor size and male sex. Complete tumor resection with negative margins was achieved and metastases were not detected. The patient presented six months later with jaundice, asterixis and elevated liver enzymes. Computerized tomography showed multiple liver hypodense lesions representing metastases. Treatment with imatinib mesylate was of no avail and the patient died 3 days later as the result of hepatic failure. Massive liver metastases can, even though rarely, be responsible for fulminant hepatic failure. Clinical and radiological follow-up are crucial in patients with GIST even after surgical resection.

Hepatic Resection for Gastrointestinal Stromal Tumor Liver Metastases

2009 ◽  
Vol 23 (1) ◽  
pp. 115-127 ◽  
Author(s):  
Stephane Zalinski ◽  
Martin Palavecino ◽  
Eddie K. Abdalla
Keyword(s):  
Liver Metastases ◽  
Hepatic Resection ◽  
Gastrointestinal Stromal Tumor ◽  
Stromal Tumor

scholarly journals Complete response to second-line chemotherapy with sunitinib of a gastrointestinal stromal tumor: A case report

2017 ◽  
Vol 7 (1) ◽  
pp. 93-97 ◽  
Author(s):  
Tsuyoshi Shirakawa ◽  
Tomoya Hirata ◽  
Kosuke Maemura ◽  
Toshiyuki Goto ◽  
Yoshiya Shimao ◽  
...  
Keyword(s):  
Case Report ◽  
Gastrointestinal Stromal Tumor ◽  
Complete Response ◽  
Stromal Tumor ◽  
Second Line ◽  
Second Line Chemotherapy ◽  
Line Chemotherapy

scholarly journals Gastrointestinal stromal tumor (GIST) with liver metastases

Medicine ◽  
2017 ◽  
Vol 96 (46) ◽  
pp. e8240 ◽  
Author(s):  
Yi-Nan Shi ◽  
Yong Li ◽  
Li-Ping Wang ◽  
Zhen-Hua Wang ◽  
Xiao-Bo Liang ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Gastrointestinal Stromal Tumor ◽  
Stromal Tumor
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