Hib-DTaP-hepatitis-B-poliovirus-vaccine/pneumococcal-vaccine-conjugate

2020 ◽  
Vol 1798 (1) ◽  
pp. 136-136
Keyword(s):  
Hepatitis B ◽  
Pneumococcal Vaccine ◽  
Vaccine Conjugate

Response to Immunizations Following Allogeneic HCT with Adjuvant Rituximab Therapy.

Blood ◽  
2005 ◽  
Vol 106 (11) ◽  
pp. 3242-3242 ◽  
Author(s):  
Mary Pao ◽  
Esperanza B. Papadopoulos ◽  
Farid Boulad ◽  
Hugo Castro-Malaspina ◽  
Ann Jakubowski ◽  
...  
Keyword(s):  
T Cell ◽  
Hepatitis B ◽  
B Cell ◽  
Pneumococcal Vaccine ◽  
Cell Function ◽  
Pneumococcal Vaccination ◽  
Hepatitis B Vaccination ◽  
Allogeneic Hct ◽  
Initial Series ◽  
Adequate Response

Abstract Use of anti-CD20 monoclonal antibody after allogeneic HCT for the treatment EBV lymphoma or viremia, autoimmune cytopenias, and the prevention or treatment of recurrent NHL has become more frequent. There is limited data on the effect of this therapy on specific antibody production following allogeneic HCT. We therefore examined the response to standard childhood immunizations of 30 patients, including 20 adults (>18 years of age) who received rituximab following a T cell depleted (n=26) or unmodified (n=4) HCT at our institution. T cell function was assessed in vitro by proliferative response to PHA and B cell reconstitution was confirmed by recovery of CD19+ and CD20+ circulating lymphocytes. Patients received a median (range) of 4 (1–12) doses of rituximab, with 15 patients receiving 4–6 doses. The median age of the patient population was 28.5 years with a range of 0.8–63.0 years. Children (median age: 8.5 yrs) received a transplant from an unrelated (n=7), HLA mismatched related (n=2), or HLA matched related (n=1) donor and adults (median age: 42.5 yrs), received a transplant from an unrelated (n=7), HLA mismatched related (n=2), or HLA-matched related (n=11) donor. Patients were vaccinated when their PHA response was at least 75% of the lower limit of normal and CD20+ cells were >100/ul. Vaccination was initiated at a median of 270 and 525 days following the last dose of rituximab in children and adults, respectively. A two to 3-fold rise in titers following a series of 3 tetanus and IPV vaccinations occurred in 19 of 21 and 19 of 19 evaluable patients, respectively. Although 8 of 9 children responded to the H flu conjugate vaccine, only 5 of 13 adults mounted an adequate response. Eighteen patients received the recombinant Hepatitis B vaccine. Nine responded following the initial series (5/7 children, 4/11 adults). Two of three patients who failed initial Hepatitis B vaccination, responded to a second series (1 child, 1 adult). Response to pneumococcal vaccination was the least consistent. None of 11 adults who received the unconjugated 23-valent pneumococcal vaccine developed an adequate response. In view of this observation, children given rituximab were immunized with the conjugated pneumococcal vaccine. Four of eight children responded to the initial series, and two additional children responded following a second series. These preliminary data suggest that both adult and pediatric patients given rituximab following an allogeneic HCT can mount successful antibody responses to standard T-helper cell dependent vaccines. However, B cell responses to T cell independent vaccines may be particularly impaired. Larger prospective trials, stratified by age, comparing vaccine responses in patients following allogeneic transplant in the presence or absence of post transplant rituximab therapy are warranted.

scholarly journals Sistem Informasi Jadwal Imunisasi Kesehatan Bayi Dan Balita Berbasis Sms Gateway

Respati ◽  
2018 ◽  
Vol 13 (1) ◽  
Author(s):  
Ahmad Chusyairi ◽  
Tri Kurnia Hadi Muktining Nur ◽  
David Haryanto
Keyword(s):  
Information System ◽  
Hepatitis B ◽  
Haemophilus Influenzae ◽  
Pneumococcal Vaccine ◽  
Haemophilus Influenzae Type ◽  
Haemophilus Influenzae Type B ◽  
Immunization Schedule ◽  
Type B ◽  
Mobile Operator ◽  
Sim Card

INTISARISistem informasi pada Puskesmas untuk mengingatkan jadwal imunisasi (Bacillus Celmette-Guerin (BCG), Hepatitis B, Polio, Difteri, Pertusis, dan Tetanus (DTP), Campak, Haemophilus influenzae type b (Hib), Pneumococcal Vaccine (PCV), Influenza dan lainnya) pada kader Posyandu dan orang tua bayi dan balita masih bersifat manual, sehingga menyulitkan Unit Pelaksana Teknis Daerah (UPTD). Puskesmas di Kabupaten Banyuwangi dalam melakukan perekapan data kesehatan dan monitoring tingkat derajat kesehatan khususnya bayi dan balita di kabupaten Banyuwangi. SMS Gateway adalah salah satu jenis SMS yang mengirimkan pesan jadwal imunisasi ke handphone kader Posyandu dan orang tua bayi dan balita dimana tarif normal SMS diberlakukan sesuai dengan operator seluler dan SIM Card ditempatkan pada modem eksternal yang dihubungkan dengan komputer. Oleh karena itu, salah satu upaya yang dilakukan Puskesmas di Kabupaten Banyuwangi adalah Sistem Informasi Jadwal Imunisasi Kesehatan Bayi dan Balita Berbasis SMS Gateway, sehingga mempermudah dalam menginformasikan jadwal imunisasi kepada kader Posyandu dan orang tua bayi dan balita. Hasil dari penelitian ini adalah sistem informasi jadwal imuninasi kesehatan bayi dan balita berbasis sms gateway dan menghasilkan laporan jadwal sms terkirim dan laporan ringkasan Posyandu.Kata Kunci−jadwal, imunisasi, bayi, balita, SMS Gateway ABSTRACTInformation systems at Puskesmas to remind the immunization schedule (Bacillus Celmette-Guerin (BCG), Hepatitis B, Polio, Diphtheria, Pertussis and Tetanus (DTP), Measles, Haemophilus influenzae type b (Hib), Pneumococcal Vaccine (PCV), Influenza and others) in Posyandu cadres and parents of infants and toddlers are still manual, making it difficult for the Regional Technical Implementation Unit (UPTD). Puskesmas in Banyuwangi District in conducting health data recording and monitoring of health degree level especially babies and babies in Banyuwangi district. SMS Gateway is one type of SMS that sends immunization schedule messages to mobile Posyandu cadres and infant and toddler parents where normal SMS rates apply according to the mobile operator and SIM Card is placed on an external modem connected to the computer. Therefore, one of the efforts made by the Puskesmas in Banyuwangi Regency is the Immunization Information System of Infant and Toddler Health Based SMS Gateway, making it easier to inform the immunization schedule to Posyandu cadres and parents of infants and toddlers.The result of this research is information system of immunization schedule of infant and toddler health based on sms gateway and produce report of sms schedule sent and summary report of Posyandu.Keywords−schedule, immunization, infant, toddler, SMS Gateway

scholarly journals Summary Of Original Papers

1970 ◽  
Vol 19 (2) ◽  
pp. 37-38
Author(s):  
No Author
Keyword(s):  
Immune Response ◽  
Cardiopulmonary Bypass ◽  
Hepatitis B ◽  
Total Hip Replacement ◽  
Pneumococcal Vaccine ◽  
Hip Replacement ◽  
Controlled Trial ◽  
Total Hip ◽  
Impaired Immune Response

Prostacyclin Administration During Cardiopulmonary Bypass In Man                      D.B. Longmore, J.Graeme Bennett, P.M. Hoyle, M.A. Smith, A.Gregory, T.Osivand, W.A.Jones Impaired Immune Response Of Splenectomised Patient To Polyvalent Pneumococcal Vaccine              Stephen W. Hosea, Cynthia G. Burch, Eric J. Brown, Richard A.Berg, Michael M.Drank Prophylactic Cefazolin Versus Placebo In Total Hip Replacement             C. Hill, F.Mazas, R.Flamant, J.Evrard Randomised Placebo-Controlled Trial Of Hepatitis B Surface vaccine In French Haemodialysis Units:II, Haemodialysis Patients              Jean Crosnier, Paul Jungers, Anne Marie             Courouce, Agnes Laplanche, Ellen Benhamou, Francoise    Degos,Bernard Lacour, Paul Prunet, Yvannex Cerisier, Pierre Guesry

scholarly journals P44 Vaccine in pediatric chronic kidney disease (CKD) and hemodialysis

2020 ◽  
Vol 105 (9) ◽  
pp. e29.2-e30
Author(s):  
Aichetou Camara ◽  
Anaïs Razurel ◽  
Christelle Moreau ◽  
Thérésa Kwon ◽  
Marion Caseris ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Hepatitis B ◽  
Infectious Diseases ◽  
Pneumococcal Vaccine ◽  
Working Group ◽  
Hepatitis A ◽  
Pediatric Nephrology ◽  
Immunization Schedule ◽  
Pediatric Dialysis

AimsChronic kidney disease is a major risk factor of vaccine preventable infectious diseases due to the altered immune system and the natural evolution of the disease. There are differences in the prescription of some vaccines for this population. The aim of this study is to elaborate a vaccination protocol for chronic kidney disease and haemodialysis patients for a better immunization coverage, care and prevention against preventable infectious diseases.MethodsThe study was conducted by a multidisciplinary team composed by pharmacists, infectious disease paediatrician and nephrology paediatricians. After a literature research (in Medline with MeSH terms: ‘Kidney Failure, Chronic’, ‘Renal Dialysis’ and ‘Vaccines’)1 2, we compared the French immunization schedule3 for the general population with patient with chronic kidney disease or haemodialysis patients and confront it to the physician practice in our nephrology unit. For each vaccine, we collected the following data: indication, any difference concerning dose, schedule, re-administration, antibody titration and reason for these differences.ResultsThe literature analysis showed disparate practices among countries and even medical centres. The most concerned vaccines were: hepatitis A and B virus vaccine, pneumococcal vaccine, flu and measles vaccines. The difference between vaccine scheduled concerned the indication (meningococcus A, B, C, Y and W135, papillomavirus), dose (hepatitis B), the schedule (hepatitis B, hepatitis A, pneumococcal, measles), re-administration (hepatitis B, varicella), antibody titration (hepatitis B, varicella). Patients with chronic kidney disease are more susceptible to develop hepatitis B infection. As for adult population, the haemodialysis patients are vaccinated with double dose4 of hepatitis B vaccine. The antibodies titration at our hospital is made twice a year and anti-HBs level needed are 30 to 50 UI/mL. Hepatitis A is a recommended vaccine for risk population including haemodialysis patients and chronic kidney disease patients. The vaccination schedule is the same for haemodialysis patients with two doses but the second dose is administered earlier, i.e. six months after the first with an antibody screening. For the pneumococcal vaccine, an additional dose is administered at 3 month of age for premature and at risk children and the conjugated vaccine potentiates the polyosidic vaccine. For measles, the second dose may be omitted if the antibody titration confirms the protection to allow the patient to be registered earlier on the renal transplant list. Flu vaccination is recommended with the same dose and schedule that the other patients, but tetravalent vaccines should always be chosen.ConclusionsChildren with chronic kidney disease or on haemodialysis are more at risk of vaccine preventable infectious diseases and should be vaccinated earlier before beginning dialysis. The specific immunization schedule will be presented and may be used by other hospital and countries for concerned patients.ReferencesBakkaloğlu SA, et al. Vaccination Practices in Pediatric Dialysis Patients Across Europe. A European Pediatric Dialysis Working Group and European Society for Pediatric Nephrology Dialysis Working Group Study. Nephron 2018;138:280–286.Costa NCP, da Canhestro MR, Soares CMBM & Rodrigues JS. Monitoring of post-vaccination anti-HBs titles vaccine in children and adolescents in the pre-dialysis of chronic kidney disease. Braz. J. Nephrol. 2017;39:296–304.DGS_Anne.M, DICOM_Jocelyne.M, DGS_Anne.M & DICOM_Jocelyne.M. Le calendrier vaccinal. Ministère des Solidarités et de la Santé (2019). Available at: https://solidarites-sante.gouv.fr/prevention-en-sante/preserver-sa-sante/vaccination/calendrier-vaccinal (Accessed: 28th June 2019)Misurac JM, et al. Immunogenicity of augmented compared with standard dose hepatitis B vaccine in pediatric patients on dialysis: a midwest pediatric nephrology consortium study. Clin. J. Am. Soc. Nephrol 2017;12:772–778.

Sign in / Sign up

Export Citation Format

Share Document