scholarly journals Duloxetine Exposure During Pregnancy and the Risk of Spontaneous and Elective Abortion: A Danish Nationwide Observational Study

Author(s):  
Mikkel Zöllner Ankarfeldt ◽  
Janne Petersen ◽  
Jon Trærup Andersen ◽  
Maria Fernanda Scantamburlo Fernandes ◽  
Hu Li ◽  
...  
Author(s):  
Edda Vesteinsdottir ◽  
Martin Ingi Sigurdsson ◽  
Magnus Gottfredsson ◽  
Asbjorn Blondal ◽  
Sigurbergur Karason

Author(s):  
Fabiana Fiasca ◽  
Mauro Minelli ◽  
Dominga Maio ◽  
Martina Minelli ◽  
Ilaria Vergallo ◽  
...  

The COVID-19 outbreak disproportionately affected the elderly and areas with higher population density. Among the multiple factors possibly involved, a role for air pollution has also been hypothesized. This nationwide observational study demonstrated the significant positive relationship between COVID-19 incidence rates and PM2.5 and NO2 levels in Italy, both considering the period 2016–2020 and the months of the epidemic, through univariate regression models, after logarithmic transformation of the variables, as the data were not normally distributed. That relationship was confirmed by a multivariate analysis showing the combined effect of the two pollutants, adjusted for the old-age index and population density. An increase in PM2.5 and NO2 concentrations by one unit (1 µg/m3) corresponded to an increase in incidence rates of 1.56 and 1.24 × 104 people, respectively, taking into account the average levels of air pollutants in the period 2016–2020, and 2.79 and 1.24 × 104 people during March–May 2020. Considering the entire epidemic period (March–October 2020), these increases were 1.05 and 1.01 × 104 people, respectively, and could explain 59% of the variance in COVID-19 incidence rates (R2 = 0.59). This evidence could support the implementation of targeted responses by focusing on areas with low air quality to mitigate the spread of the disease.


2020 ◽  
Vol 124 (5) ◽  
pp. 638-647 ◽  
Author(s):  
Stavros G. Memtsoudis ◽  
Megan Fiasconaro ◽  
Ellen M. Soffin ◽  
Jiabin Liu ◽  
Lauren A. Wilson ◽  
...  

2019 ◽  
Vol 66 ◽  
pp. 144-148 ◽  
Author(s):  
Kyung Eun Nam ◽  
Seong Hoon Lim ◽  
Joon Sung Kim ◽  
Bo Young Hong ◽  
Han Young Jung ◽  
...  

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