On the transport of inorganic phosphate and malate in rat-liver mitochondria

1969 ◽  
Vol 189 (2) ◽  
pp. 311-314 ◽  
Author(s):  
S. Papa ◽  
N.E. Lofrumento ◽  
M. Loglisci ◽  
E. Quagliariello
Keyword(s):  
Rat Liver ◽  
Inorganic Phosphate ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Transport Of Inorganic Phosphate

scholarly journals The transport of inorganic phosphate by the mitochondrial dicarboxylate carrier

1973 ◽  
Vol 134 (3) ◽  
pp. 769-774 ◽  
Author(s):  
R. N. Johnson ◽  
J. B. Chappell
Keyword(s):  
Rat Liver ◽  
Inorganic Phosphate ◽  
Dicarboxylic Acids ◽  
Liver Mitochondria ◽  
Exchange Mechanism ◽  
Rat Liver Mitochondria ◽  
Exchange Diffusion ◽  
Low Concentrations ◽  
Transport Of Inorganic Phosphate

1. N-Ethylmaleimide inhibited the influx and efflux of Pi in rat liver mitochondria. 2. The efflux was stimulated by either succinate or malate in the presence of N-ethylmaleimide, and this stimulation was reversed by 2-n-butylmalonate. 2-Oxoglutarate and citrate, even in the presence of low concentrations of malate, were relatively ineffective in stimulating efflux of Pi under these conditions, as was glutamate. 3. By using radioactively labelled Pi and dicarboxylate ions an exchange was demonstrated, the stoicheiometry of which was 1.3±0.5 dicarboxylate ions:1 Pi (n=10). 4. An exchange between unlabelled and labelled Pi in the presence of N-ethylmaleimide was found which was sensitive to 2-n-butylmalonate. 5. It is concluded that the mitochondrial dicarboxylate carrier can transport phosphate by an exchange diffusion with certain penetrant dicarboxylic acids or with phosphate itself. The exchange mechanism is sensitive to 2-n-butylmalonate but is unaffected by N-ethylmaleimide; the action of mersalyl in this context is commented on.

Inorganic phosphate stimulated Tl+ effects on rat liver mitochondria

Mitochondrion ◽  
2006 ◽  
Vol 6 (5) ◽  
pp. 12-13
Author(s):  
Sergey Korotkov ◽  
Larisa Emelyanova ◽  
Vadim Glazunov
Keyword(s):  
Rat Liver ◽  
Inorganic Phosphate ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria

scholarly journals Effect of Inorganic Phosphate on Iron-Induced Lipid Peroxidation in Rat Liver Mitochondria.

1993 ◽  
Vol 16 (11) ◽  
pp. 1094-1098 ◽  
Author(s):  
Hideto KAWANO ◽  
Kentaro KOGURE ◽  
Kenji FUKUZAWA ◽  
Hiroshi TERADA
Keyword(s):  
Lipid Peroxidation ◽  
Rat Liver ◽  
Inorganic Phosphate ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria

Inorganic phosphate stimulates the toxic effects of Tl+in rat liver mitochondria

2008 ◽  
Vol 22 (3) ◽  
pp. 148-157 ◽  
Author(s):  
Sergey M. Korotkov ◽  
Larisa V. Emel'yanova ◽  
Olga V. Yagodina
Keyword(s):  
Rat Liver ◽  
Inorganic Phosphate ◽  
Liver Mitochondria ◽  
Toxic Effects ◽  
Rat Liver Mitochondria
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