Endogenous event-related potentials in obsessive-compulsive disorder

1990 ◽  
Vol 28 (2) ◽  
pp. 92-98 ◽  
Author(s):  
James Towey ◽  
Gerard Bruder ◽  
Eric Hollander ◽  
David Friedman ◽  
Hulya Erhan ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Event Related Potentials ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Related Potentials

Psychophysiological and clinical value of event-related potentials in obsessive-compulsive disorder

1997 ◽  
Vol 42 (1) ◽  
pp. 46-56 ◽  
Author(s):  
Pierre M. Morault ◽  
Marc Bourgeois ◽  
Jérôme Laville ◽  
Claude Bensch ◽  
Jacques Paty
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Event Related Potentials ◽  
Clinical Value ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Related Potentials

Modulation of error monitoring in obsessive–compulsive disorder by individually tailored symptom provocation

2017 ◽  
Vol 47 (12) ◽  
pp. 2071-2080 ◽  
Author(s):  
D. Roh ◽  
J.-G. Chang ◽  
S. W. Yoo ◽  
J. Shin ◽  
C.-H. Kim
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Flanker Task ◽  
Event Related Potentials ◽  
Therapeutic Interventions ◽  
Error Monitoring ◽  
Obsessive Compulsive ◽  
Symptom Provocation ◽  
Compulsive Disorder ◽  
Control Subjects ◽  
Related Potentials

BackgroundThe enhanced error monitoring in patients with obsessive–compulsive disorder (OCD), typically measured with the error-related negativity (ERN), has been found to be temporally stable and independent of symptom expression. Here, we examined whether the error monitoring in patients with OCD could be experimentally modulated by individually tailored symptom provocation.MethodTwenty patients with OCD and 20 healthy controls performed a flanker task in which OCD-relevant or neutral pictures were presented prior to a flanker stimulus. An individualized stimulus set consisting of the most provoking images in terms of OCD symptoms was selected for each patient with OCD. Response-locked event-related potentials were recorded and used to examine the error-related brain activity.ResultsPatients with OCD showed larger ERN amplitudes than did control subjects in both the OCD-symptom provocation and neutral conditions. Additionally, while patients with OCD exhibited a significant increase in the ERN under the OCD-symptom provocation condition when compared with the neutral condition, control subjects showed no variation in the ERN between the conditions.ConclusionsOur results strengthen earlier findings of hyperactive error monitoring in OCD, as indexed by higher ERN amplitudes in patients with OCD than in controls. Importantly, we showed that the patients’ overactive error-signals were experimentally enhanced by individually tailored OCD-symptom triggers, thus suggesting convincing evidence between OCD-symptoms and ERN. Such findings imply that therapeutic interventions should target affective regulation in order to alleviate the perceived threatening value of OCD triggers.

Executive control in obsessive-compulsive disorder: event-related potentials in a Go/Nogo task

2007 ◽  
Vol 114 (12) ◽  
pp. 1595-1601 ◽  
Author(s):  
M. Ruchsow ◽  
K. Reuter ◽  
L. Hermle ◽  
D. Ebert ◽  
M. Kiefer ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Executive Control ◽  
Event Related Potentials ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Related Potentials

Event-related potentials in drug-naïve pediatric patients with obsessive-compulsive disorder

2015 ◽  
Vol 230 (2) ◽  
pp. 394-399 ◽  
Author(s):  
Kazuhiko Yamamuro ◽  
Toyosaku Ota ◽  
Yoko Nakanishi ◽  
Hiroki Matsuura ◽  
Kosuke Okazaki ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Pediatric Patients ◽  
Event Related Potentials ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Related Potentials ◽  
Drug Naïve
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