Cytostatic activity of chlamydocin, a rapidly inactivated cyclic tetrapeptide

1974 ◽  
Vol 10 (12) ◽  
pp. 801-808 ◽  
Author(s):  
H. Stähelin ◽  
A. Trippmacher
Keyword(s):  
Cytostatic Activity ◽  
Cyclic Tetrapeptide

Cytostatic 6-Arylpurine Nucleosides II. Synthesis of Sugar-Modified Derivatives: 9-(2-Deoxy-β-D-erythro-pentofuranosyl)-, 9-(5-Deoxy-β-D-ribofuranosyl)- and 9-(2,3-Dihydroxypropyl)-6-phenylpurines

2000 ◽  
Vol 65 (11) ◽  
pp. 1683-1697 ◽  
Author(s):  
Michal Hocek ◽  
Antonín Holý ◽  
Ivan Votruba ◽  
Hana Dvořáková
Keyword(s):  
Cross Coupling ◽  
Cytostatic Activity ◽  
Coupling Reactions ◽  
Cross Coupling Reactions ◽  
Highly Active ◽  
Phenylboronic Acids

9-(2-Deoxy-β-D-erythro-pentofuranosyl)-6-(4-substituted phenyl)purines, 9-(5-deoxy-β-D-ribofuranosyl)-6-(4-substituted phenyl)purines and 9-(2,3-dihydroxypropyl)-6-(4-substituted phenyl)purines were prepared by the Suzuki-Miyaura cross-coupling reactions of the corresponding protected 9-substituted 6-chloropurines with substituted phenylboronic acids followed by MeONa mediated deprotection. In contrast to the highly active 6-phenylpurine ribonucleosides, the title compounds did not show any considerable cytostatic activity.

scholarly journals Massiliamide, a cyclic tetrapeptide with potent tyrosinase inhibitory properties from the Gram-negative bacterium Massilia albidiflava DSM 17472T

2020 ◽  
Author(s):  
Andri Frediansyah ◽  
Jan Straetener ◽  
Heike Brötz-Oesterhelt ◽  
Harald Gross
Keyword(s):  
Absolute Configuration ◽  
Inhibitory Activity ◽  
Liquid Culture ◽  
Spectroscopic Analysis ◽  
2D Nmr ◽  
Negative Bacterium ◽  
Gram Negative ◽  
The Absolute ◽  
Potent Inhibitory Activity ◽  
Cyclic Tetrapeptide

AbstractA cyclic tetrapeptide, designated massiliamide, was isolated from the liquid culture of the Gram-negative bacterium Massilia albidiflava DSM 17472T. The structure was elucidated through extensive spectroscopic analysis, including HR-MS and 1D and 2D NMR experiments. The absolute configuration was determined using the Marfey´s method. Massiliamide showed potent inhibitory activity towards tyrosinase with an IC50 value of 1.15 µM and no cytotoxicity.

ChemInform Abstract: JM47, a Cyclic Tetrapeptide HC-Toxin Analogue from a Marine Fusarium Species

ChemInform ◽  
2010 ◽  
Vol 33 (38) ◽  
pp. no-no
Author(s):  
Zhong Jiang ◽  
Marc-Olivier Barret ◽  
Kenneth G. Boyd ◽  
David R. Adams ◽  
Alan S. F. Boyd ◽  
...  
Keyword(s):  
Fusarium Species ◽  
Hc Toxin ◽  
Cyclic Tetrapeptide

In vitro cytostatic activity of 9-demethoxyporothramycin B

1995 ◽  
Vol 30 (7-8) ◽  
pp. 647-650 ◽  
Author(s):  
C Tempête ◽  
GH Werner ◽  
F Favre ◽  
A Rojas ◽  
N Langlois
Keyword(s):  
Cytostatic Activity

Staphylopeptide A, a new cyclic tetrapeptide from culture broth of Staphylococcus sp.

2015 ◽  
Vol 13 ◽  
pp. 11-14 ◽  
Author(s):  
Amgad I.M. Khedr ◽  
Gamal A. Mohamed ◽  
Mohamed A.A. Orabi ◽  
Sabrin R.M. Ibrahim ◽  
Koji Yamada
Keyword(s):  
Culture Broth ◽  
Cyclic Tetrapeptide

Cytolytic and cytostatic activity on tumor cells of circulating human monocytes

1979 ◽  
Vol 23 (1) ◽  
pp. 18-27 ◽  
Author(s):  
Alberto Mantovani ◽  
Thomas R. Jerrells ◽  
Jack H. Dean ◽  
Ronald B. Herberman
Keyword(s):  
Tumor Cells ◽  
Cytostatic Activity ◽  
Human Monocytes

Saccharopolytide A, a new cyclic tetrapeptide with rare 4-hydroxy-proline moieties from the deep-sea derived actinomycete Saccharopolyspora cebuensis MCCC 1A09850

2017 ◽  
Vol 32 (14) ◽  
pp. 1627-1631 ◽  
Author(s):  
Chun-Lan Xie ◽  
Siwen Niu ◽  
Jin-Mei Xia ◽  
Kun Peng ◽  
Gai-Yun Zhang ◽  
...  
Keyword(s):  
Deep Sea ◽  
Hydroxy Proline ◽  
Cyclic Tetrapeptide
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