Hymenolepis diminuta: Further characterization of the membrane-bound acid phosphatase activity associated with the brush border membrane of the tapeworm's tegument

1991 ◽  
Vol 72 (4) ◽  
pp. 362-367 ◽  
Author(s):  
Peter W. Pappas
1980 ◽  
Vol 26 (3) ◽  
pp. 371-382
Author(s):  
D B Robinson ◽  
R H Glew

Abstract Increased acid phosphatase activity in the serum and tissues of patients with Gaucher's disease has now been recognized for two decades, but as yet no relation has been established between the enzyme and the etiology and progress of the disease. Here, we review results obtained by various investigators, ranging from a consideration of the methods used for the evaluation of serum acid phosphatase in Gaucher's disease to the most recent findings regarding the purification and characterization of two acid phosphatase isoenzymes from the spleen from patients with Gaucher's disease. We also discuss the intracellular location of tissue acid phosphatase in patients with Gaucher's disease and its contribution to the increased activity in serum.


1971 ◽  
Vol 49 (11) ◽  
pp. 2053-2057 ◽  
Author(s):  
Esther Cohen ◽  
Y. Shain ◽  
Y. Ben-Shaul ◽  
A. M. Mayer

The zymogen body fraction of pea seeds was further investigated as to the content and localization of additional enzymes. This fraction was previously shown to contain an inactive form of amylopectin-1,6-glucosidase. An acid phosphatase was found with an optimum pH of 5.4. ATP or GTP were the preferred natural substrates, although there was no effect of Mg2+, K+, or Na+ ions on this acid nucleotide phosphatase activity. Cytochemical methods show that the ATPase is membrane-bound and that these bodies have only a single limiting membrane. No RNAse activity could be found; however, there was considerable β-galactosidase activity. It is concluded that these zymogen bodies are a distinct class of subcellular organelles in plants.


1980 ◽  
Vol 26 (3) ◽  
pp. 371-382 ◽  
Author(s):  
D B Robinson ◽  
R H Glew

Abstract Increased acid phosphatase activity in the serum and tissues of patients with Gaucher's disease has now been recognized for two decades, but as yet no relation has been established between the enzyme and the etiology and progress of the disease. Here, we review results obtained by various investigators, ranging from a consideration of the methods used for the evaluation of serum acid phosphatase in Gaucher's disease to the most recent findings regarding the purification and characterization of two acid phosphatase isoenzymes from the spleen from patients with Gaucher's disease. We also discuss the intracellular location of tissue acid phosphatase in patients with Gaucher's disease and its contribution to the increased activity in serum.


1986 ◽  
Vol 91 (5) ◽  
pp. 1234-1242 ◽  
Author(s):  
In-Sung Song ◽  
Masahiro Yoshioka ◽  
Roger H. Erickson ◽  
Soichiro Miura ◽  
Difu Guan ◽  
...  

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