scholarly journals Changing patterns of histone acetylation and RNA synthesis of the developing and ageing rat brain

FEBS Letters ◽  
1978 ◽  
Vol 85 (2) ◽  
pp. 301-304 ◽  
Author(s):  
H.-I. Sarkander ◽  
E. Knoll-Köhler
1971 ◽  
Vol 1 (3) ◽  
pp. 254-259 ◽  
Author(s):  
A. J. Dewar ◽  
H. W. Reading

SYNOPSISAn attempt has been made to explain the changes in uric acid levels observed in the phase of manic depressive illness by suggesting that they may be a reflection of changes in brain RNA metabolism. The effect of prolonged lithium administration on RNA synthesis in rat brain and liver has been studied. Differences in the rate of turnover of brain RNA between the lithium-treated and saline control animals have been observed.


1983 ◽  
Vol 5 (6) ◽  
pp. 737-740 ◽  
Author(s):  
F. Cicirata ◽  
E. Geremia ◽  
A. Custorella ◽  
A. Vanella

1969 ◽  
Vol 47 (1) ◽  
pp. 47-50 ◽  
Author(s):  
Shan-Ching Sung

The in vitro synthesis of DNA as measured by the incorporation of thymidine-2-14C into DNA has been studied for various regions of the infant rat brain. Both intact cerebellum and cell-free extracts of cerebellum from newborn and infant rat brain showed a very rapid rate of DNA synthesis which was highest around 6 days after birth and decreased rapidly thereafter up to 18 days. This DNA synthesis in developing rat brain was strongly inhibited by hydroxyurea but was much less sensitive than was RNA synthesis to inhibition by actinomycin D.


1990 ◽  
Vol 194 (3) ◽  
pp. 811-823 ◽  
Author(s):  
Lidia C. BOFFA ◽  
Janis WALKER ◽  
Thelma A. CHEN ◽  
Richard STERNER ◽  
Maria R. MARIANI ◽  
...  

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