scholarly journals Nishizawa, M., Y. Hayakawa, N. Yanaihara and H. Okamoto, Nucleotide sequence divergence and functional constraint in VIP precursor mRNA evolution between human and rat (1985) FEBS Letters 183, 55-59

FEBS Letters ◽  
1985 ◽  
Vol 185 (2) ◽  
pp. 339-339
Keyword(s):  
Nucleotide Sequence ◽  
Sequence Divergence ◽  
Functional Constraint ◽  
Nucleotide Sequence Divergence ◽  
Precursor Mrna ◽  
Mrna Evolution

scholarly journals Defining natural species of bacteria: clear-cut genomic boundaries revealed by a turning point in nucleotide sequence divergence

BMC Genomics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 489 ◽  
Author(s):  
Le Tang ◽  
Yang Li ◽  
Xia Deng ◽  
Randal N Johnston ◽  
Gui-Rong Liu ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
Turning Point ◽  
Sequence Divergence ◽  
Clear Cut ◽  
Nucleotide Sequence Divergence

scholarly journals A new Puumala hantavirus subtype in rodents associated with an outbreak of Nephropathia epidemica in South-East Germany in 2004

2006 ◽  
Vol 134 (6) ◽  
pp. 1333-1344 ◽  
Author(s):  
S. ESSBAUER ◽  
J. SCHMIDT ◽  
F. J. CONRATHS ◽  
R. FRIEDRICH ◽  
J. KOCH ◽  
...  
Keyword(s):  
Nucleotide Sequence ◽  
East Germany ◽  
Local Population ◽  
Sequence Divergence ◽  
Puumala Virus ◽  
Bank Voles ◽  
Nucleotide Sequence Divergence ◽  
Western Germany ◽  
North Western ◽  
Trapping Sites

A micro-epidemic of hantavirus infections occurred in Lower Bavaria, South-East Germany, starting in April 2004. While only three cases were registered from 2001 to 2003, a dramatically increased number of clinically apparent human hantavirus infections (n=38) was observed in 2004, plus seven additional cases by June 2005. To determine the reservoir responsible for the infections, a total of 43 rodents were trapped in Lower Bavaria. Serological and genetic investigations revealed that Puumala virus (PUUV) is dominant in the local population of bank voles. Partial PUUV S segment nucleotide sequences originating from bank voles at four different trapping sites in Lower Bavaria showed a low divergence (up to 3·1%). This is contrasted by a nucleotide sequence divergence of 14–16% to PUUV strains detected in Belgium, France, Slovakia or North-Western Germany. PUUV sequences from bank voles in Lower Bavaria represent a new PUUV subtype which seems to be responsible for the observed increase of human hantavirus infections in 2004–2005.

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