Captopril-induced taste disturbance

The Lancet ◽  
1993 ◽  
Vol 342 (8866) ◽  
pp. 304 ◽  
Author(s):  
Ian Boyd
Keyword(s):  
Taste Disturbance

Rate of Recovery of Taste Function after Preservation of Chorda Tympani Nerve in Middle Ear Surgery with Special Reference to Type of Disease

2003 ◽  
Vol 112 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Masafumi Sakagami ◽  
Mieko Sone ◽  
Keijiro Fukazawa ◽  
Kojiro Tsuji ◽  
Yasuo Mishiro
Keyword(s):  
Recovery Of Function ◽  
Inflammatory Diseases ◽  
Chronic Otitis Media ◽  
Normal Function ◽  
Middle Ear Surgery ◽  
Chorda Tympani ◽  
Chorda Tympani Nerve ◽  
Taste Disturbance ◽  
Postoperative Symptoms ◽  
Rate Of Recovery

To study the recovery of function of the chorda tympani nerve, we examined by electrogustometry 79 patients (83 ears) with both preoperative normal function of the nerve and operative preservation of the nerve, every 2 days during hospitalization and at 6 months after surgery. For symptoms such as tongue numbness and taste disturbance, patients with noninflammmatory (NI) diseases (13/20 or 65.0%) showed a significantly higher rate of symptoms than did patients with chronic otitis media (COM; 13/35 or 37.1%) at 2 weeks after surgery (p = .032). The patients with NI diseases (5/20 or 25.0%) tended to show a higher rate of symptoms than did the COM patients (2/35 or 5.7%) or cholesteatoma patients (2/28 or 7.1%) at 6 months after surgery. The rate of recovery of the EGM threshold to normal at 2 weeks after surgery was significantly lower in NI disease patients (6/20 or 30.0%) than in COM patients (23/ 35 or 62.9%) or cholesteatoma patients (19/28 or 67.9%; p = .015 and .008, respectively). Thus, the patients with NI diseases had postoperative symptoms and elevation of EGM threshold more frequently than did the patients with inflammatory diseases.

Menopausal Symptoms Are Associated With Oral Sensory Complaints in Perimenopausal Women: An Observational Study

2021 ◽  
Author(s):  
Tomoharu Taga ◽  
Kayoko Ito ◽  
Kiyoshi Takamatsu ◽  
Mariko Ogawa ◽  
Saori Funayama ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Univariate Analysis ◽  
Menopausal Symptoms ◽  
Study Cohort ◽  
Tongue Coating ◽  
Taste Disturbance ◽  
Factors Associated ◽  
Oral Sensory ◽  
Perimenopausal Women ◽  
Burning Mouth

Abstract Background: Perimenopausal women experience a wide variety of systemic symptoms: hot flashes, sweating, psychiatric symptoms and various oral sensory complaints (OSC). OSC in perimenopausal women include xerostomia, taste disturbance and burning mouth. However, the factors associated with these OSC have not been identified. The purpose of this investigation was to elucidate the factors associated with OSC in perimenopausal women．Methods: The study cohort comprised 43 perimenopausal women aged 45–55 years. Data on medical history, medications, menstrual status, menopausal symptoms, xerostomia, taste disturbance and burning mouth were collected. Volumes of unstimulated and stimulated saliva were measured. Tongue coating was evaluated according to a tongue coating index. Univariate analysis was performed to identify factors significantly associated with having xerostomia, taste disturbance, burning mouth and more than two OSC (2OSC). Next, the factors strongly associated with these symptoms were examined by logistic regression analysis.Results: The number of menopausal symptoms was significantly higher, and volume of unstimulated saliva significantly lower in participants with xerostomia, taste disturbance, burning mouth or 2OSC than in those without these characteristics. Agents targeting the central nervous system were more frequently taken by participants with burning mouth and 2OSC than by those without these characteristics. According to logistic regression analysis, the number of menopausal symptoms was an explanatory variable for xerostomia, taste disturbance, burning mouth and 2OSC. Conclusions: Our findings suggested that OSC associated with the number of menopausal symptoms. Management of menopausal symptoms may decrease OSC, leading to improved quality of life of perimenopausal women.

scholarly journals Platelet-Rich Plasma Myringoplasty: A New Office Procedure for the Repair of Small Tympanic Membrane Perforations

2017 ◽  
Vol 96 (8) ◽  
pp. 312-326 ◽  
Author(s):  
Mohammad Waheed El-Anwar ◽  
Ismail Elnashar ◽  
Yaser Ahmad Foad
Keyword(s):  
Tympanic Membrane ◽  
Platelet Rich Plasma ◽  
Invasive Procedure ◽  
Minimally Invasive Procedure ◽  
Office Procedure ◽  
Taste Disturbance ◽  
Tympanic Membrane Perforations ◽  
Single Piece ◽  
Study Population ◽  
A Prospective Study

We conducted a prospective study to assess the effectiveness of a platelet-rich plasma hourglass graft in the repair of small tympanic membrane perforations as an office-based procedure. Our study population was made up of 25 patients—10 men and 15 women, aged 19 to 45 years (mean: 30.4 ± 7.2)—who each underwent repair of one eardrum. After administration of topical anesthesia, a single piece of platelet-rich plasma approximately double the size of the perforation was obtained from each patient's intravenous blood sample. After the margin of the perforation was freshened, the platelet-rich plasma was placed in an hourglass configuration, with equal portions lying medial and lateral to the perforation. Successful perforation repair was achieved in 21 of the 25 ears (84%). No patient developed an infection, hearing impairment, tinnitus, vertigo, bleeding, taste disturbance, or hyperkeratosis. We conclude that office-based platelet-rich plasma myringoplasty is a safe and effective minimally invasive procedure that is suitable for repairing small tympanic membrane perforations.

scholarly journals Taste disturbance after tonsillectomy: a rare but significant complication- a case report

2015 ◽  
Vol 10 (1) ◽  
pp. 110-112 ◽  
Author(s):  
Misbah Al Kabir ◽  
Sultana Dil Afsana
Keyword(s):  
Case Report ◽  
Rare Complication ◽  
Armed Forces ◽  
Glossopharyngeal Nerve ◽  
Phenothiazine Derivatives ◽  
Taste Disturbance ◽  
Significant Complication ◽  
Medical College ◽  
Minimal Trauma ◽  
Possible Cause

Introduction: Tonsillectomy is the most commonly performed procedure and generally regarded as a safe surgery. Taste disturbance is a very rare complication after tonsillectomy, with very few reports in the literature. The most possible cause of this rare complication is direct or indirect damage to the glossopharyngeal nerve or its lingual branch (LBGN). Aim: To report a very rare complication of the most commonly performed procedure i.e. tonsillectomy. Case Report: The case is a 32 years old lady who complained of taste disturbance following tonsillectomy that was performed for chronic tonsillitis. As treatment patient was given Trifluoparazine Hydrochloride a Phenothiazine derivatives and Vit B6 + Vit B12. Patient recovered after 4 months postoperatively. Conclusion: Tonsillectomy should be performed with minimal trauma to the tonsillar bed to avoid injury to the Glossopharyngeal nerve or its lingual branch (LBGN) and all patients should be informed of the risk of post-operative taste disturbance after tonsillectomy. DOI: http://dx.doi.org/10.3329/jafmc.v10i1.22935 Journal of Armed Forces Medical College Bangladesh Vol.10(1) 2014

scholarly journals TASTE DISTURBANCE AFTER TONSILLECTOMY

1994 ◽  
Vol 97 (6) ◽  
pp. 1079-1089 ◽  
Author(s):  
KENJI OHTUKA ◽  
HIROSHI TOMITA ◽  
YUKI YAMAUCHI ◽  
HIDETO KITAGOH
Keyword(s):  
Taste Disturbance

Taste disturbance after stapes surgery: an evaluation of frequency, severity, duration, and quality-of-life

2016 ◽  
Vol 137 (1) ◽  
pp. 39-43 ◽  
Author(s):  
Katarina Berling Holm ◽  
Johan Knutsson ◽  
Karin Strömbäck ◽  
Niklas Danckwardt Lillieström ◽  
Georgios Papatziamos ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stapes Surgery ◽  
Taste Disturbance

Fampridine and Acetazolamide in EA2 and Related Familial EA: A Prospective Randomized Placebo-controlled Trial

2020 ◽  
pp. 10.1212/CPJ.0000000000001017
Author(s):  
Carolin Muth ◽  
Julian Teufel ◽  
Ludger Schöls ◽  
Matthis Synofzik ◽  
Christiana Franke ◽  
...  
Keyword(s):  
Crossover Trial ◽  
Controlled Trial ◽  
Random Sequence ◽  
Positive Family History ◽  
Phase Iii ◽  
Prolonged Release ◽  
Taste Disturbance ◽  
Double Blind ◽  
Episodic Ataxia Type 2 ◽  
Gastrointestinal Complaints

AbstractObjectiveWe determine the efficacy and safety of the treatment with prolonged-release 4-aminopyridine (fampridine) and acetazolamide for patients with episodic ataxia type 2 (EA2). Therefore, 30 patients with EA2 were treated with a random sequence of fampridine, acetazolamide, and placebo in a three-period crossover trial.MethodsA total of 30 patients with EA2 (eight female; aged 20-71 years; 18 genetically confirmed, four with a positive family history, eight with the clinical diagnosis) were enrolled in this phase III, randomised, double-blind, placebo-controlled, three-period crossover trial. Each period lasted 12 weeks with a four-week washout-period. Each patient received a random sequence of 20 mg/d fampridine, 750 mg/d acetazolamide, and placebo. The primary endpoint was the number of attacks during the last 30 days within the 12-week treatment-period. Participants, caregivers, and those assessing the outcomes were blinded to the intervention.ResultsCompared to placebo, fampridine reduced the number of attacks to 63% (95% CI 54% - 74%) and acetazolamide to 52% (95% CI 46% - 60%). A total of 39 (26.5%) adverse events were observed under treatment with fampridine (mostly tingling paraesthesia, and fatigue), 66 (44.9%) happened under acetazolamide (mostly taste disturbance, gastrointestinal complaints), and 42 (28.6%) under placebo (mostly gastrointestinal complaints).ConclusionBoth fampridine and acetazolamide significantly reduce the number of attacks in patients with EA2 and related EA in comparison to placebo. Fampridine 10 mg twice daily had fewer side effects than acetazolamide 250 mg three times daily.

scholarly journals Effects of Teton in the Treatment of Taste Disturbance

2004 ◽  
Vol 97 (6) ◽  
pp. 563-567
Author(s):  
Akihiro Ikui ◽  
Minoru Ikeda ◽  
Ayako Komiyama ◽  
Takuma Yoshikawa ◽  
Nao Sekiguchi ◽  
...  
Keyword(s):  
Taste Disturbance

Taste disturbance after stapes surgery – clinical and experimental study

2009 ◽  
Vol 129 (sup562) ◽  
pp. 71-78 ◽  
Author(s):  
Shinya Miuchi ◽  
Masafumi Sakagami ◽  
Kenzo Tsuzuki ◽  
Koichi Noguchi ◽  
Yasuo Mishiro ◽  
...  
Keyword(s):  
Experimental Study ◽  
Stapes Surgery ◽  
Taste Disturbance
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