Aprotinin enhances growth of tumor cells in serum free media

1989 ◽  
Vol 41 (2) ◽  
pp. 265
1976 ◽  
Vol 2 (1) ◽  
pp. 311-313 ◽  
Author(s):  
Charity Waymouth ◽  
Don S. Varnum

1988 ◽  
Vol 24 (1) ◽  
pp. 42-52 ◽  
Author(s):  
David Danielpour ◽  
Terry L. Riss ◽  
Masami Ogasawara ◽  
David A. Sirbasku

1961 ◽  
Vol 236 (2) ◽  
pp. 285-288
Author(s):  
John Papaconstantinou ◽  
Sidney P. Colowick
Keyword(s):  

1965 ◽  
Vol 240 (7) ◽  
pp. 2791-2796
Author(s):  
Edward B. Goldberg ◽  
Harold M. Nitowsky ◽  
Sidney P. Colowick
Keyword(s):  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Samatha Bhat ◽  
Pachaiyappan Viswanathan ◽  
Shashank Chandanala ◽  
S. Jyothi Prasanna ◽  
Raviraja N. Seetharam

AbstractBone marrow-derived mesenchymal stromal cells (BM-MSCs) are gaining increasing importance in the field of regenerative medicine. Although therapeutic value of MSCs is now being established through many clinical trials, issues have been raised regarding their expansion as per regulatory guidelines. Fetal bovine serum usage in cell therapy poses difficulties due to its less-defined, highly variable composition and safety issues. Hence, there is a need for transition from serum-based to serum-free media (SFM). Since SFM are cell type-specific, a precise analysis of the properties of MSCs cultured in SFM is required to determine the most suitable one. Six different commercially available low serum/SFM with two different seeding densities were evaluated to explore their ability to support the growth and expansion of BM-MSCs and assess the characteristics of BM-MSCs cultured in these media. Except for one of the SFM, all other media tested supported the growth of BM-MSCs at a low seeding density. No significant differences were observed in the expression of MSC specific markers among the various media tested. In contrary, the population doubling time, cell yield, potency, colony-forming ability, differentiation potential, and immunosuppressive properties of MSCs varied with one another. We show that SFM tested supports the growth and expansion of BM-MSCs even at low seeding density and may serve as possible replacement for animal-derived serum.


1983 ◽  
Vol 11 (01n04) ◽  
pp. 69-73 ◽  
Author(s):  
Y.M. Choy ◽  
T.T. Kwok ◽  
K.P. Fung ◽  
C.Y. Lee

A number of food materials or drugs have been screened for the effect on the growth and development of transplantable Ehrlich ascites tumor cells. Growth of tumor-bearing mice was significantly inhibited by feeding garlic as well as some amino acids. These materials significantly reduced the total number of free tumor cells growing in the peritoneal cavity of mice and prolonged significantly the length of time for 50% death of tumor-bearing mice.


1988 ◽  
Vol 111 (1) ◽  
pp. 125-129 ◽  
Author(s):  
Hanne Blaehr ◽  
Joergen Ladefoged

1991 ◽  
Vol 82 (8) ◽  
pp. 883-885 ◽  
Author(s):  
Masanori Terashima ◽  
Kenichiro Ikeda ◽  
Chihaya Maesawa ◽  
Hidenobu Kawamura ◽  
Yorikazu Niitsu ◽  
...  

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