Antibody of patients with Guillain-Barré syndrome mediates complement-dependent cytolysis of rat Schwann cells: Susceptibility to cytolysis reflects Schwann cell phenotype

1994 ◽  
Vol 49 (1-2) ◽  
pp. 145-152 ◽  
Author(s):  
Suneeti Sawant-Mane ◽  
Alden Estep ◽  
Carol Lee Koski
Keyword(s):  
Schwann Cell ◽  
Schwann Cells ◽  
Guillain Barre Syndrome ◽  
Cell Phenotype ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

Schwann cell nuclear remodelling and formation of nuclear and coiled bodies in Guillain-Barré syndrome

1996 ◽  
Vol 92 (4) ◽  
pp. 386-394 ◽  
Author(s):  
M. T. Berciano ◽  
E. Calle ◽  
M. A. Andres ◽  
J. Berciano ◽  
M. Lafarga
Keyword(s):  
Schwann Cell ◽  
Guillain Barre Syndrome ◽  
Coiled Bodies ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals Perisynaptic Schwann cells phagocytose nerve terminal debris in a mouse model of Guillain‐Barré syndrome

2020 ◽  
Vol 25 (2) ◽  
pp. 143-151 ◽  
Author(s):  
Madeleine E. Cunningham ◽  
Gavin R. Meehan ◽  
Sophie Robinson ◽  
Denggao Yao ◽  
Rhona McGonigal ◽  
...  
Keyword(s):  
Mouse Model ◽  
Schwann Cells ◽  
Nerve Terminal ◽  
Guillain Barre Syndrome ◽  
Guillain Barré Syndrome ◽  
Perisynaptic Schwann Cells ◽  
Guillain Barré

Serum-mediated Schwann cell cytotoxicity in the Guillain-Barre syndrome

Neurology ◽  
1984 ◽  
Vol 34 (9) ◽  
pp. 1240-1240 ◽  
Author(s):  
R. P. Lisak ◽  
D. Kuchmy ◽  
P. J. Armati-Gulson ◽  
M. J. Brown ◽  
A. J. Sumner
Keyword(s):  
Schwann Cell ◽  
Guillain Barre Syndrome ◽  
Cell Cytotoxicity ◽  
Guillain Barré Syndrome ◽  
Guillain Barré

scholarly journals The Neuroimmunology of Guillain-Barré Syndrome and the Potential Role of an Aging Immune System

2021 ◽  
Vol 12 ◽  
Author(s):  
Kathleen M. Hagen ◽  
Shalina S. Ousman
Keyword(s):  
Immune System ◽  
Schwann Cells ◽  
Potential Role ◽  
Immune Cell ◽  
Guillain Barre Syndrome ◽  
Age Related ◽  
Guillain Barré Syndrome ◽  
Autoimmune Condition ◽  
Guillain Barré

Guillain-Barré syndrome (GBS) is a paralyzing autoimmune condition affecting the peripheral nervous system (PNS). Within GBS there are several variants affecting different aspects of the peripheral nerve. In general, there appears to be a role for T cells, macrophages, B cells, and complement in initiating and perpetuating attacks on gangliosides of Schwann cells and axons. Of note, GBS has an increased prevalence and severity with increasing age. In addition, there are alterations in immune cell functioning that may play a role in differences in GBS with age alongside general age-related declines in reparative processes (e.g., delayed de-differentiation of Schwann cells and decline in phagocytic ability of macrophages). The present review will explore the immune response in GBS as well as in animal models of several variants of the disorder. In addition, the potential involvement of an aging immune system in contributing to the increased prevalence and severity of GBS with age will be theorized.

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