Identification of immunoreactive somatostatin in the rat Harderian gland: Regulation of its content by growth hormone, beta-adrenergic agonists and calcium channel blockers

Peptides ◽  
1988 ◽  
Vol 9 (3) ◽  
pp. 571-574 ◽  
Author(s):  
M. Puig-Domingo ◽  
J.M. Guerrero ◽  
R.J. Reiter ◽  
M.A. Peinado ◽  
I. Sabry ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Calcium Channel ◽  
Calcium Channel Blockers ◽  
Harderian Gland ◽  
Channel Blockers ◽  
Adrenergic Agonists ◽  
Beta Adrenergic ◽  
Beta Adrenergic Agonists

EFFECTS OF INHIBITORS OF CATECHOLAMINE SYNTHESIS AND CATECHOLAMINE AGONISTS ON MORPHINE- AND HYPOGLYCAEMIA-INDUCED RELEASE OF GROWTH HORMONE IN THE RAT

1978 ◽  
Vol 76 (2) ◽  
pp. 365-366 ◽  
Author(s):  
M. T. BLUET-PAJOT ◽  
C. SCHAUB
Keyword(s):  
Growth Hormone ◽  
Adrenergic Agonists ◽  
Beta Adrenergic ◽  
Catecholamine Synthesis ◽  
Gh Secretion ◽  
Beta Adrenergic Agonists ◽  
Urethane Anaesthesia ◽  
Regulation Of Growth

Unité de Neuroendocrinologie, INSERM, U.159, 2 ter Rue d'Alesia, 75014 Paris, France (Received 16 August 1977) It is known that catecholamines play an important role in the regulation of growth hormone (GH) secretion, but the effects of dopamine and alpha- and beta-adrenergic agonists on the release of GH in the rat are controversial (Collu, Fraschini, Visconti & Martini, 1972; Kato, Dupre & Beck, 1973; Durand, Martin & Brazeau, 1977). It has been proposed (Bluet-Pajot, Schaub & Nassiet, 1976; Bluet-Pajot & Schaub, 1977; Durand et al. 1977) that the conflicting data obtained in the rat may be due to the anaesthesia; most of the GH responses reported to be atypical in the rat, compared with those of primates, were obtained under urethane anaesthesia, which is known to result in long-lasting and irreversible endocrine imbalance. In contrast, neurotransmitters or experimental hypoglycaemia do not appear to induce paradoxical GH responses in rats treated

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