Homeotic Mutation

2013 ◽  
pp. 510-511 ◽  
Author(s):  
T.R. Bürglin
Keyword(s):  
Homeotic Mutation

Sevenless: A Cell-Specific Homeotic Mutation of the Drosophila Eye

Science ◽  
1986 ◽  
Vol 231 (4736) ◽  
pp. 400-402 ◽  
Author(s):  
A. TOMLINSON ◽  
D. F. READY
Keyword(s):  
Drosophila Eye ◽  
A Cell ◽  
Homeotic Mutation

Ieafy hull sterile 1 Is a Homeotic Mutation in a Rice MADS Box Gene Affecting Rice Flower Development

2000 ◽  
Vol 12 (6) ◽  
pp. 871 ◽  
Author(s):  
Jong-Seong Jeon ◽  
Seonghoe Jang ◽  
Sichul Lee ◽  
Jongmin Nam ◽  
Chanhong Kim ◽  
...  
Keyword(s):  
Flower Development ◽  
Mads Box ◽  
Mads Box Gene ◽  
Homeotic Mutation

scholarly journals Genetic and developmental characteristics of the homeotic mutation bx1 of Drosophila

Development ◽  
1983 ◽  
Vol 76 (1) ◽  
pp. 251-264
Author(s):  
Ernesto Sánchez-Herrero ◽  
Ginés Morata
Keyword(s):  
Temperature Shift ◽  
Clonal Analysis ◽  
Temperature Sensitive ◽  
Wing Structures ◽  
Partial Inactivation ◽  
Homeotic Mutation ◽  
Developmental Characteristics ◽  
Proliferation Period

The mutations at the bithorax locus produce a transformation of anterior haltere into anterior wing. The bx1 allele presents unusual features when compared with other bx alleles. The phenotype of bx1 homozygotes is temperature sensitive but only with regard to the distal and not to the proximal transformation, thus suggesting two different components in the bithorax transformation. The phenotype of bx1 homozygotes is stronger than that of bx1 over the deletion of the gene, suggesting a trans interaction of the bx1 chromosomes which results in mutual partial inactivation. We show by temperature shift and clonal analysis experiments that the decision on whether to differentiate haltere or wing structures is taken at the end of the proliferation period of the mutant disc.

scholarly journals A Homeotic Mutation Changes Legume Nodule Ontogeny into Actinorhizal-Type Ontogeny

2020 ◽  
Vol 32 (6) ◽  
pp. 1868-1885 ◽  
Author(s):  
Defeng Shen ◽  
Ting Ting Xiao ◽  
Robin van Velzen ◽  
Olga Kulikova ◽  
Xiaoyun Gong ◽  
...  
Keyword(s):  
Homeotic Mutation

Homeotic Mutation

2001 ◽  
pp. 962-963
Author(s):  
T. Bürglin
Keyword(s):  
Homeotic Mutation

scholarly journals A new homeotic mutation in the Drosophila bithorax complex removes a boundary separating two domains of regulation.

1990 ◽  
Vol 9 (8) ◽  
pp. 2579-2585 ◽  
Author(s):  
H. Gyurkovics ◽  
J. Gausz ◽  
J. Kummer ◽  
F. Karch
Keyword(s):  
Bithorax Complex ◽  
Homeotic Mutation

Genetic complementation of a floral homeotic mutation, apetala3, with an Arabidopsis thaliana gene homologous to DEFICIENS of Antirrhinum majus

1994 ◽  
Vol 26 (1) ◽  
pp. 465-472 ◽  
Author(s):  
Hiroyuki Okamoto ◽  
Azusa Yano ◽  
Hideaki Shiraishi ◽  
Kiyotaka Okada ◽  
Yoshiro Shimura
Keyword(s):  
Arabidopsis Thaliana ◽  
Genetic Complementation ◽  
Antirrhinum Majus ◽  
Homeotic Mutation ◽  
Floral Homeotic

scholarly journals The Drosophila homeotic mutation Nasobemia (AntpNs) and its revertants: an analysis of mutational reversion.

Genetics ◽  
1994 ◽  
Vol 138 (3) ◽  
pp. 709-720 ◽  
Author(s):  
P B Talbert ◽  
R L Garber
Keyword(s):  
Mutant Gene ◽  
Cell Types ◽  
Spontaneous Mutant ◽  
Wild Type ◽  
Homeotic Transformation ◽  
Adult Head ◽  
Homeotic Mutation ◽  
Different Cell Types ◽  
Structure And Activity

Abstract The homeotic gene Antennapedia (Antp) controls determination of many different cell types in the thorax and abdomen of Drosophila melanogaster. The spontaneous mutant allele Nasobemia (AntpNs) and its revertants have been widely used to infer normal Antp gene function but have not themselves been thoroughly characterized. Our analysis reveals that AntpNs consists of an internal 25-kb partial duplication of the Antp gene as well as a complex insertion of > 40 kb of new DNA including two roo transposons. The duplication gives the mutant gene three Antp promoters, and transcripts from each of these are correctly processed to yield functional ANTP proteins. At least two of the promoters are ectopically active in the eye-antenna imaginal discs, leading to homeotic transformation of the adult head. A molecular and genetic description of several AntpNs revertants shows them to be diverse in structure and activity, including a restoration of the wild type, rearrangements separating two of the AntpNs promoters from the coding sequences, and protein nulls and hypomorphs affecting expression from all three of the promoters. Finally, one revertant has a suppressing lesion in the osa locus far away from Antp. These features explain the unusual homozygous viable nature of AntpNs, suggest a mechanism by which its homeotic transformation occurs, and exemplify the diversity of ways in which mutational reversion can take place.

Octopod, a homeotic mutation of the moth Manduca sexta, influences the fate of identifiable pattern elements within the CNS

Development ◽  
1989 ◽  
Vol 105 (3) ◽  
pp. 621-628 ◽  
Author(s):  
R. Booker ◽  
J.W. Truman
Keyword(s):  
Central Nervous System ◽  
Manduca Sexta ◽  
Ventral Surface ◽  
Wild Type ◽  
The Central Nervous System ◽  
Homeotic Mutation ◽  
Thoracic Legs ◽  
Homeotic Mutations ◽  
Anterior Direction ◽  
Slight Deformation

Octopod (Octo) is a mutation of the moth Manduca sexta, which results in the homeotic transformation of the ventral surface of the first (A1) and less often the second (A2) abdominal segments in the anterior direction. The extent of the transformation ranges from a slight deformation of the ventral cuticle, up to the formation of miniature thoracic legs on A1. The extent of the transformation is always less within A2 as compared to A1. A genetic analysis revealed that Octo is an autosomal mutation which shows incomplete dominance. The effect of this mutation on the central nervous system (CNS) was assessed by examining the distribution and fate of the postembryonic neuroblasts in the segmental ganglia of Octo larvae. In each of the thoracic ganglia of wild-type larvae, there is a set of 45–47 neuroblasts; a reduced but homologous array of 24 and 10 neuroblasts are found in A1 and A2, respectively. Ganglion A1 of Octo larvae had 1 to 6 supernumerary neuroblasts, and 20% of the A2 ganglia showed a single ectopic neuroblast. The supernumerary neuroblasts corresponded to identifiable neuroblasts normally found in more anterior ganglia. The Octo mutation also influenced the mitotic activity of stem cells normally present in A1. In this case, the neuroblasts generated a lineage of cells that were typical of a thoracic location rather than A1. These data demonstrate that homeotic mutations can influence the fate of identifiable pattern elements within the CNS of an insect.

Sign in / Sign up

Export Citation Format

Share Document