Single-Cell Omics in Personalized Medicine

2019 ◽  
pp. 221-236
Author(s):  
Alessandro Buriani ◽  
Stefano Fortinguerra ◽  
Vincenzo Sorrenti ◽  
Daniela Gabbia ◽  
Maria Carrara
2014 ◽  
Vol 1 (11) ◽  
pp. 20-22
Author(s):  
Yan Zhang ◽  
Joyce Peng

Nanoscale ◽  
2015 ◽  
Vol 7 (44) ◽  
pp. 18504-18514 ◽  
Author(s):  
Felipe T. Lee-Montiel ◽  
Peter Li ◽  
P. I. Imoukhuede

Multicolor Quantum dots multiplexing single cell analysis of membrane receptors for the development of better patient therapies and the advance of personalized medicine.


OBM Genetics ◽  
2021 ◽  
Vol 5 (4) ◽  
pp. 1-1
Author(s):  
Sean J. O’Sullivan ◽  
◽  

Advances in clinical psychiatry have been less than hoped for relative to the achievements in neuroscience. However, developments in neuromodulation and psychedelic therapy are promising. The efficacy of such treatments and canonical pharmacotherapies benefit from genetics and personalized medicine. Moreover, recent studies on the perturbation of transcription, including chromatin remodeling, in mental illness emphasized the importance of single-cell qPCR as an investigatory method that bolstered psychiatry. This technique demonstrated chromatin remodeling as a biomarker for addiction and the underlying mechanism of depression. If personalized medicine, along with canonical and newer therapies, can mediate and regulate transcription, epidemics in depression and addiction can be mitigated. This motivates investigators to continue to use single-cell transcription measures in models of mental illness for translational medicine.


RSC Advances ◽  
2015 ◽  
Vol 5 (65) ◽  
pp. 52436-52443 ◽  
Author(s):  
Rıfat Emrah Özel ◽  
Akshar Lohith ◽  
Wai Han Mak ◽  
Nader Pourmand

Within a large clonal population cells are not identical, and the differences between intracellular pH levels of individual cells may be important indicators of heterogeneity that can be relevant in clinical practice, such as personalized medicine.


2014 ◽  
Vol 34 (14) ◽  
pp. 20-21
Author(s):  
Yan Zhang ◽  
Joyce Peng

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