Two-dimensional difference in gel electrophoresis for biomarker discovery

2020 ◽  
pp. 209-214 ◽  
Author(s):  
Haleem J. Issaq ◽  
Timothy D. Veenstra
Keyword(s):  
Gel Electrophoresis ◽  
Biomarker Discovery ◽  
Two Dimensional

scholarly journals Biomarker discovery for personalized medicine in bone and soft-tissue sarcoma patients using two-dimensional gel electrophoresis

2012 ◽  
Vol 56 (1) ◽  
pp. 25-29
Author(s):  
Daisuke Kubota ◽  
Yoshiyuki Suehara ◽  
Kazutaka Kikuta ◽  
Kazuo Kaneko ◽  
Akira Kawai ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Personalized Medicine ◽  
Soft Tissue Sarcoma ◽  
Gel Electrophoresis ◽  
Biomarker Discovery ◽  
Two Dimensional ◽  
Two Dimensional Gel Electrophoresis

Diversity of Glycoprotein Deficiencies in Glanzmann’s Thrombasthenia

1985 ◽  
Vol 54 (03) ◽  
pp. 626-629 ◽  
Author(s):  
M Meyer ◽  
F H Herrmann
Keyword(s):  
High Resolution ◽  
Gel Electrophoresis ◽  
Type Ii ◽  
Two Dimensional ◽  
Two Dimensional Gel Electrophoresis ◽  
Structural Variant ◽  
Glanzmann’S Thrombasthenia ◽  
Crossed Immunoelectrophoresis ◽  
Glanzmann's Thrombasthenia ◽  
Platelet Proteins

SummaryThe platelet proteins of 9 thrombasthenic patients from 7 families were analysed by high resolution two-dimensional gel electrophoresis (HR-2DE) and crossed immunoelectrophoresis (CIE). In 7 patients both glycoproteins (GPs) IIb and Ilia were absent or reduced to roughly the same extent. In two related patients only a trace of GP Ilb-IIIa complex was detected in CIE, but HR-2DE revealed a glycopeptide in the position of GP Ilia in an amount comparable to type II thrombasthenia. This GP Ilia-like component was neither recognized normally by anti-GP Ilb-IIIa antibodies nor labeled by surface iodination. In unreduced-reduced two-dimensional gel electrophoresis two components were observed in the region of GP Ilia. The assumption of a structural variant of GP Ilia in the two related patients is discussed.

Comparative Two-Dimensional Gel Electrophoresis of Trypanosoma cruzi Mammalian-Stage Forms in an Alkaline pH Range

2015 ◽  
Vol 22 (12) ◽  
pp. 1066-1075 ◽  
Author(s):  
Adriana Magalhães ◽  
Rayner Queiroz ◽  
Izabela Bastos ◽  
Jaime Santana ◽  
Marcelo Sousa ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Gel Electrophoresis ◽  
Two Dimensional ◽  
Alkaline Ph ◽  
Two Dimensional Gel Electrophoresis ◽  
Ph Range
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