Biocompatibility of modified polyethersulfone membranes by blending an amphiphilic triblock co-polymer of poly(vinyl pyrrolidone)–b-poly(methyl methacrylate)–b-poly(vinyl pyrrolidone)

The characteristics of two types of porous polymers: poly(methyl methacrylate) and copolymers of methyl methacrylate and acrylamide were investigated in this study. Poly(methyl methacrylate) was synthesized in suspension, using ethylene glycol dimethacrylate as the cross-linking agent, poly(vinyl pyrrolidone) as the protective colloid, and benzoyl peroxide as the initiator. The synthesis of poly(methyl methacrylate-co-acrylamide) was initiated in emulsion in the presence of dioctyl sulfosuccinate sodium salt, followed by a sol-gel process, and completely reacted to the solid state. Potassium persulfate was used as the initiator, and tetramethylol glycoluril as the cross-linking agent. Both types of syntheses were carried out in the presence of ethyl acetate. The porosity, specific surface and distribution of the pore sizes of the obtained polymers were determined by mercury porosimetry. The polymers were used as inert carriers for the immobilization of enzymes and whole cells of Saccharomyces cerevisiae yeast.

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Fabrication and cytocompatibility evaluation for blood-compatible polyethersulfone membrane modified by a synthesized poly (vinyl pyrrolidone)-block -poly (acrylate-graft -poly(methyl methacrylate))-block -poly-(vinyl pyrrolidone)

Polymers for Advanced Technologies ◽

10.1002/pat.3718 ◽

2015 ◽

Vol 27 (5) ◽

pp. 591-596 ◽

Cited By ~ 8

Author(s):

Fen Ran ◽

Haiming Song ◽

Lang Ma ◽

Xiaoqin Niu ◽

Jiayu Wu ◽

...

Keyword(s):

Methyl Methacrylate ◽

Vinyl Pyrrolidone ◽

Poly Methyl Methacrylate ◽

Polyethersulfone Membrane ◽

Poly Vinyl Pyrrolidone

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Fabrication of Substituted-Hydroxyapatite/Poly(vinyl pyrrolidone)- Poly(methyl methacrylate) Biocomposites for Bone Tissue Engineering Applications

Asian Journal of Chemistry ◽

10.14233/ajchem.2021.23385 ◽

2021 ◽

Vol 33 (11) ◽

pp. 2774-2780

Author(s):

G. Priya ◽

N. Vijayakumari

Keyword(s):

Mechanical Properties ◽

Compressive Strength ◽

Methyl Methacrylate ◽

Antimicrobial Activities ◽

Vinyl Pyrrolidone ◽

Gram Negative Bacteria ◽

Structural Investigations ◽

Gram Negative ◽

Poly Methyl Methacrylate ◽

Poly Vinyl Pyrrolidone

Present work based on the development and incorporation of zinc-cerium substituted hydroxyapatite (ZCHA) nanoparticles into the host material of the dual polymer blend of poly(vinyl pyrrolidone) (PVD)-poly(methyl methacrylate) (PMMA). Numerous characterization techniques such as FTIR, XRD and SEM-EDX have been used in morphological and structural investigations of prepared nanoparticles and ZCHA reinforced PMMA-PVD biocomposites. The mechanical properties of ZCHA/PVD-PMMA biocomposites, like compressive strength was evaluated. To examine the biocompatibility of biocomposites, hemocompatibility experiments have been carried out. The antimicrobial activities of biocomposites toward Gram-positive and Gram-negative bacteria have also been tested and the cytotoxic existence of biocomposites has been evaluated using the MTT assay experiment. The developed ZCHA/PVD-PMMA biocomposites is suggested to provide the finest medicinal benefits in the application of biomaterials.

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