Smart pills for gastrointestinal diagnostics and therapy

Magnetic fluids with nanoparticles dispersed in water or oils offer attractive applications in biomedicine and industry. Biocompatible magnetic fluids are used for diagnostics and therapy in medical applications, in pharmacy, and biosensors. Application of ferrofluids is expanding into energy conservation, faster and efficient cooling, and hence better performance in a wide variety of practical applications (in heat exchangers, mainly in micro-cooling systems). For the study of the influence of an external magnetic field on the aggregation processes of magnetic nanoparticles in magnetic fluids, acoustic spectroscopy was used. The jump changes of the magnetic flux density at various temperatures influenced the acoustic attenuation. The measured changes were results of nanoparticle aggregations into new structures.

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СОВРЕМЕННЫЕ ПОДХОДЫ К ДИАГНОСТИКЕ И ЛЕЧЕНИЮ АНГИООТЕКОВ В ПЕДИАТРИИ

Rossiiskii Allergologicheskii ZHurnal ◽

10.36691/raj.2019.2.53333 ◽

2019 ◽

Author(s):

A.R. Denisova ◽

A.N. Pampura

Keyword(s):

Clinical Manifestations ◽

Personalized Therapy ◽

Diagnostics And Therapy ◽

Selection Of

Ангиоотеки довольно часто встречаются в детском возрасте. Эффективность ведения детей с ангиоотеками определяется пониманием патогенеза заболевания и подбором персонифицированной терапии. В статье представлены сведения о классификации, клинических проявлениях, диагностике и терапии как брадикинин-, так и гистаминергических ангиоотеков.Angioedema often occurs in childhood. The effectiveness of the management of children with angioedema is determined by understanding the pathogenesis of the disease and the selection of personalized therapy. This article provides information on the classification, clinical manifestations, diagnostics and therapy of both bradykinin and histaminergic angioedema.

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Heat Shock Protein 70 kDa as a Target for Diagnostics and Therapy of Cardiovascular and Cerebrovascular Diseases

Current Pharmaceutical Design ◽

10.2174/1381612825666190329123924 ◽

2019 ◽

Vol 25 (6) ◽

pp. 710-714 ◽

Cited By ~ 2

Author(s):

Ekaterina V. Konstantinova ◽

Natalia S. Chipigina ◽

Marina H. Shurdumova ◽

E.I. Kovalenko ◽

Alexander M. Sapozhnikov

Keyword(s):

Myocardial Infarction ◽

Ischemic Stroke ◽

Heat Shock ◽

Cerebrovascular Diseases ◽

Peripheral Blood Lymphocytes ◽

Neuroprotective Effects ◽

Adverse Conditions ◽

Shock Proteins ◽

Diagnostics And Therapy ◽

Main Factor

Acute focal ischemia is a main factor of pathogenesis of a number of widespread cardiovascular and cerebrovascular diseases, in particular, myocardial infarction and ischemic stroke. It is known that under the conditions of ischemia expression of intracellular heat shock proteins (HSPs), especially HSP70, grows greatly irrespective of the cell type. This stress-induced cell response is connected with cytoprotective properties of HSP70. The protective functions of HSP70 contribute to the cell survival under adverse conditions and inhibit development of programmed cell death. It was shown, that the level of HSP70 increases in cardiomyocytes and brain cells in response to ischemia, that was connected with cardioprotective and neuroprotective effects. Besides, in recent years, clinical studies of HSP70 have demonstrated elevated level of HSP70 in peripheral blood lymphocytes in groups of patients with ischemic stroke and myocardial infarction. This review indicates that HSP70 can serve as a target for developing new approaches to diagnostics and therapy of cardiovascular and cerebrovascular diseases.

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