Antepartum uterine contraction patterns in twin pregnancies with and without preterm labor and delivering before or after 36 weeks

2008 ◽  
Vol 198 (5) ◽  
pp. e28-e29 ◽  
Author(s):  
Ana Rachel Hernández ◽  
Víctor Hugo González-Quintero ◽  
Niki Istwan ◽  
Debbie Rhea ◽  
Enrique Vázquez-Vera ◽  
...  
Author(s):  
Prasila Ekaputri

Objectives: To determine the cut off point of cervical length usingtransvaginal ultrasonography to predict the actual occurrence ofpreterm labor in women with threatened preterm labor. Methods: A cross sectional study with consecutive random samplingmethod. We examined 80 women with singleton pregnancycomplaining of regular, painful uterine contraction and rupturedmembrane at 24-36 weeks of gestation. Women in active labor, definedby the presence of cervical dilatation less than or equal 3 cm, and having complicationwere excluded. When the patient was admitted, a transvaginalscan was performed to measure the cervical length. Parenteralmagnesium sulfate was given as the subsequent management.The primary outcome was delivery within 24 hours of presentation.Results: We found that the optimal cut off values for cervical lengthwas 2.65 cm with sensitivity 94.4 Percent, specificity 65.4Percent, positive predictivevalue 75.4 Percent and negative predictive value 81.8 Percent. In 69cases, the cervical length was more than or 2.65 cm, with 52 patients successfullycontinued their pregnancy until more than 24 hours. In the 11cases with cervical length less than or equal 2.65 cm, delivery within 24 hours occurredin 9 cases (81,8 Percent). Conclusion: The findings of this study suggest that in women withthreatened preterm labor, cervical length more than or equal 2.65 cm may help predictthe actual occurrence of preterm labor. Keywords: cervical length, threatened preterm labor, transvaginalultrasonography


Author(s):  
Iain L. O. Buxton ◽  
Windee Crow ◽  
Shaji O. Mathew

2011 ◽  
Vol 2011 ◽  
pp. 1-6 ◽  
Author(s):  
Yasuyuki Kawagoe ◽  
Hiroshi Sameshima ◽  
Tsuyomu Ikenoue ◽  
Ichiro Yasuhi ◽  
Tatsuhiko Kawarabayashi

Objectives. We evaluated the efficacy of magnesium sulfate as a second-line tocolysis for 48 hours.Materials and Methods. A multi-institutional, simple 2-arm randomized controlled trial was performed. Forty-five women at 22 to 34 weeks of gestation were eligible, whose ritodrine did not sufficiently inhibit uterine contractions. After excluding 12 women, 33 were randomly assigned to either magnesium alone or combination (ritodrine and magnesium). The treatment was determined as effective if the frequency of uterine contraction was reduced by 30% at 48 hours of the treatment.Results. After magnesium sulfate infusion, 90% prolonged their pregnancy for >48 hours. Combination therapy was effective in 95% (18/19), which was significantly higher than 50% (7/14) for magnesium alone.Conclusion. This randomized trial revealed that combination therapy significantly reduced uterine contractions, suggesting that adjuvant magnesium with ritodrine is recommended, rather than changing into magnesium alone, when uterine contractions are intractable with ritodrine infusion.


1997 ◽  
Vol 176 (1) ◽  
pp. S35 ◽  
Author(s):  
B.H. Yoon ◽  
K.H. Park ◽  
J.N. Koo ◽  
J.H. Kwon ◽  
J.K. Jun ◽  
...  

2013 ◽  
Vol 3 (4) ◽  
pp. 183-185
Author(s):  
Ahmad El-Sheikhah ◽  
Sherif Dahab ◽  
Sherif Negm ◽  
Mohamed Momtaz

2011 ◽  
Vol 14 (5) ◽  
pp. 452-456 ◽  
Author(s):  
Chao-Nin Wang ◽  
Jannie Ying-Syuan Chen ◽  
An-Shine Chao ◽  
Po-Jen Cheng ◽  
Shuenn-Dyh Chang ◽  
...  

Multiple pregnancies are thought to be associated with a high incidence of perinatal complications such as preterm labor, preeclampsia and low birth weight. But the true mechanisms of these obstetric complications are still uncertain. The components of amniotic fluid reflect the pathophysiology features of the fetus. Amniotic fluid soluble fms-like tyrosine kinase 1(sFLT1), soluble endoglin (sENG), and adiponectin reflect the oxidative stress and pro-inflammatory status and are associated with preeclampsia and fetal growth restriction. We prospectively collected amniotic fluids during amniocentesis from singleton and twin pregnancies. Samples were analyzed for levels of sFLT1, sENG, and adiponectin by enzyme-linked immunosorbent assay. The levels of sENG and sFLT1 were significantly increased in twin pregnancies. Adiponectin was not significantly different between the two groups. These findings would suggest that twin fetuses suffer from more oxidative stress and pro-inflammatory status from the early trimesters.


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