Validity of self-reported history of Chlamydia trachomatis  infection

Screening programmes are important for the control of Chlamydia trachomatis (Ct) infection, a disease spread mainly by asymptomatic carriers. Risk factors for Ct infection were assessed in 6810 consecutive asymptomatic young women seeking contraceptive advice. All women filled in a questionnaire and were offered Ct testing. Of the 5785 who consented to testing, 425 (7.3%) were Ct culture positive. Four variables were significantly related to increased risk of being infected: age 18–23 years, duration of present relationship < 1 year, non-use of condoms, and a history of not having had a previous genital infection. It is not possible to devise screening criteria that would effectively identify women at high risk. Therefore a screening programme should be targeted at all sexually active young people. However, if after some years the programme succeeds in lowering general Ct prevalence, these factors may be important when selecting patients for Ct testing.

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Prevalence of Chlamydia trachomatis Infection, Serovar Distribution and Co-Infections with Seven High-Risk HPV Types among Italian Women with a Recent History of Abnormal Cervical Cytology

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16183354 ◽

2019 ◽

Vol 16 (18) ◽

pp. 3354 ◽

Cited By ~ 3

Author(s):

Marianna Martinelli ◽

Rosario Musumeci ◽

Alberto Rizzo ◽

Narcisa Muresu ◽

Andrea Piana ◽

...

Keyword(s):

Chlamydia Trachomatis ◽

Screening Program ◽

Hpv Infection ◽

Cervical Cytology ◽

Recent History ◽

Abnormal Cytology ◽

Chlamydia Trachomatis Infection ◽

Hpv Dna ◽

Abnormal Cervical Cytology ◽

History Of

Chlamydia trachomatis (Ct) and human papillomavirus (HPV) are the most prevalent sexually transmitted infections throughout the world. Despite the serious complications associated with chronic Ct infections in sexually active women, a screening program is not yet available in Italy. Moreover, HPV/Ct co-infections are also known to occur frequently, increasing the risk of HPV-induced carcinogenesis. The aim of this study was to evaluate the prevalence of Ct infections, the distribution of Ct serovars, and the incidences of Ct/HPV co-infections among women with a recent history of abnormal cervical cytology. Cervical samples were collected from 199 women referred for a gynecological visit following an abnormal Pap test results. All samples were tested for the presence of Ct and HPV DNA using real-time PCR assays; Ct typing of positive samples was performed by PCR–RFLP (restriction fragment length polymorphism) targeting the ompA gene. A high percentage of these women (12.8% and 21.7% with or without abnormal cytology on “retesting”, respectively) were found to be Ct positive. Serovar F was the most prevalent type in Ct positive women, followed by E and K. Ct/HPV co-infections were detected in 7% (14/199) of enrolled women, with HPV-16, HPV-51, and HPV-52 being most frequently identified in co-infections. This study provides new epidemiological data on the prevalence of Ct and associated HPV infection in women with a recent history of abnormal cervical cytology in Italy, where notification of cases is not mandatory.

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Chlamydia Trachomatis Infection in Sexually Active Women with No Known Sexual Contacts with Urethritis

Scottish Medical Journal ◽

10.1177/003693308903400307 ◽

1989 ◽

Vol 34 (3) ◽

pp. 464-466 ◽

Cited By ~ 3

Author(s):

N. Harrison ◽

I. W. Smith ◽

H. Young

Keyword(s):

Chlamydia Trachomatis ◽

Sexually Active ◽

Vaginal Symptoms ◽

Chlamydia Trachomatis Infection ◽

Sexually Transmitted ◽

Cervical Infection ◽

History Of ◽

Sexual Contacts

During the period from March 1985 to March 1986, 216 consecutive patients with vaginal symptoms were screened for cervical infection with Chlamydia trachomatis and other sexually transmitted organisms. Eleven (5%) yielded C. trachomatis without a history of recent contact with males with urethritis.

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Chlamydia Trachomatis Infection and Spontaneous Abortion

Indonesian Journal of Obstetrics and Gynecology ◽

10.32771/inajog.v9i2.1153 ◽

2021 ◽

pp. 78-81

Author(s):

Rahayu Basir ◽

Eddy Hartono ◽

Eddy R. Moeljono ◽

St. Nur Asni

Keyword(s):

Chlamydia Trachomatis ◽

Spontaneous Abortion ◽

Vaginal Discharge ◽

Study Groups ◽

Cross Sectional Study ◽

Control Group ◽

Cross Sectional ◽

Chlamydia Trachomatis Infection ◽

History Of ◽

Group 2

Abstract Objective: To determine the correlation between spontaneous abortion and Chlamydia trachomatis infection. Methods: A cross-sectional study was conducted in women who experienced spontaneous abortion. Normal pregnancies with gestational age more than equal to 37 weeks as control. Detection of C. trachomatis in the product of conception or placenta from curettage using the PCR method. Results: Positive C. trachomatis was found 3 cases in the abortion group and 4 cases in control. In the abortion group, C. trachomatis found in 1 case with vaginal discharge history and 2 cases without this history. C. trachomatis also found in 3 cases without a history of abortion. This bacteria was not found in patients with an abortion history. In the control group, 2 cases of positive C. trachomatis were found in pregnant women with or without a history of vaginal discharge and abortion, respectively. There were no significant differences regarding the positive of C. trachomatis between the two study groups regarding history of vaginal discharge and abortion. Conclusions: Spontaneous abortion does not correlate with C. trachomatis infection. Keywords: chlamydia trachomatis, infection, spontaneous abortion. Abstrak Tujuan: Untuk mengetahui hubungan antara abortus spontan dan infeksi Chlamydia trachomatis. Metode: Penelitian potong lintang dilakukan pada perempuan yang mengalami abortus spontan. Kehamilan normal dengan usia kehamilan lebih dari sama dengan 37 minggu sebagai kontrol. Deteksi C. trachomatis pada produk konsepsi atau plasenta dari kuretase menggunakan metode PCR. Hasil: C. trachomatis positif ditemukan 3 kasus pada kelompok aborsi dan 4 kasus dalam kontrol. Pada kelompok abortus spontan, C. trachomatis ditemukan pada 1 kasus dengan riwayat keputihan dan 2 kasus tanpa riwayat keputihan. C. trachomatis juga ditemukan pada 3 kasus tanpa riwayat abortus. Bakteri ini tidak ditemukan pada pasien dengan riwayat abortus. Pada kelompok kontrol, 2 kasus positif C. trachomatis masing-masing ditemukan pada perempuan hamil dengan atau tanpa riwayat keputihan dan abortus. Tidak ada perbedaan signifikan C. trachomatis positif antara kedua kelompok penelitian berdasarkan riwayat keputihan dan abortus. Kesimpulan: Abortus spontan tidak berkorelasi dengan infeksi C. trachomatis. Kata kunci: abortus spontan, chlamydia trachomatis, infeksi.

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Etiology of Pertussis Syndrome

PEDIATRICS ◽

10.1542/peds.68.1.148 ◽

1981 ◽

Vol 68 (1) ◽

pp. 148-149

Author(s):

Ben Zion Garty ◽

Moshe M. Drucker ◽

Menachem Nitzan

Keyword(s):

Chlamydia Trachomatis ◽

Laboratory Investigation ◽

Mycoplasma Pneumoniae ◽

Bordetella Pertussis ◽

Age Distribution ◽

Previous History ◽

Older Children ◽

Chlamydia Trachomatis Infection ◽

Young Infants ◽

History Of

Keller et al1 reported the interesting finding that 91 of 100 patients with pertussis syndrome were infected with Bordetella pertussis or had been exposed to this agent. Their article, however, did not mention the precise age distribution of the patients who "ranged from six weeks to adulthood." It is possible that the etiologic factors of pertussis syndrome in young infants is somewhat different from the etiology of pertussis syndrome in older children. We believe that the laboratory investigation of pertussis syndrome during the first months of life should include examinations for Chlamydia trachomatis infection in addition to the search for Bordetella, Mycoplasma pneumoniae, and viruses, as demonstrated by the following case: A 4-week-old boy with previous history of conjunctivitis was admitted because of paroxysms of staccato cough followed by occasional vomiting or cyanosis.

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The Natural History of Untreated Chlamydia trachomatis Infection in the Interval Between Screening and Returning for Treatment

Sexually Transmitted Diseases ◽

10.1097/olq.0b013e318151497d ◽

2008 ◽

Vol 35 (2) ◽

pp. 119-123 ◽

Cited By ~ 90

Author(s):

William M. Geisler ◽

Chengbin Wang ◽

Sandra G. Morrison ◽

Carolyn M. Black ◽

Claudiu I. Bandea ◽

...

Keyword(s):

Chlamydia Trachomatis ◽

Natural History ◽

Chlamydia Trachomatis Infection ◽

History Of

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Correlates of genital Chlamydial trachomatis infection in a cohort of infertile women in Ibadan, Nigeria

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20174020 ◽

2017 ◽

Vol 6 (9) ◽

pp. 3754

Author(s):

Tinuade A. Ajani ◽

Timothy Abiola Olusesan Oluwasola ◽

Chinenye G. Anaedobe ◽

Mustapha A. Ajani ◽

Samuel A. Fayemiwo ◽

...

Keyword(s):

Risk Factors ◽

Chlamydia Trachomatis ◽

Past History ◽

Sexual Partners ◽

Female Infertility ◽

Sexual History ◽

Systematic Sampling ◽

Chlamydia Trachomatis Infection ◽

Infertile Women ◽

History Of

Background: Genital Chlamydial trachomatis infection, though often asymptomatic, is an established indirect causative agent of female infertility via its activities on the tubal physiology. Many risk factors are postulated for its acquisition and the main thrust of this study was to establish the organisms’ correlates among infertile women attending gynaecologic clinic in Ibadan.Methods: A systematic sampling technique was used on each selected day to recruit women who met the inclusion criteria into the study using a sampling frame of 2. Interviewer-administered questionnaires were used to obtain attributes considered as risk factors for acquiring genital Chlamydia trachomatis infection from 150 consenting infertile women between January and November 2015. These attributes included sexual history, social status, alcohol intake and past history of sexually transmitted infections (STIs). Blood samples and endocervical swabs were subsequently taken for detection of C. trachomatis infection using polymerase chain reaction (PCR). Data analysis was done using SPSS version 20.0.Results: The mean age of the respondents was 34.1±5.6 years and 7.30% were positive for C. trachomatis. Chlamydia trachomatis infection was significantly associated with past history of gonorrhoea, history of multiple sexual partners, husband that has other sexual partners and lifetime sexual partners greater than one.Conclusions: The prevalence of asymptomatic C. trachomatis among infertile women indicated the pathogen as a potential aetiologic agent of female infertility and supported the asymptomatic nature of the infection. The risk factors found to be associated with the organisms’ infection lend out further support to the sexual transmissibility of C. trachomatis.

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