Risk Factors for Pericardial Effusion in Native Valve Infective Endocarditis and Its Influence on Outcome

2013 ◽  
Vol 112 (10) ◽  
pp. 1646-1651 ◽  
Author(s):  
Ander Regueiro ◽  
Carlos Falces ◽  
Carlos Cervera ◽  
Ana del Rio ◽  
Juan C. Paré ◽  
...  
2021 ◽  
Vol 14 (8) ◽  
pp. e244312
Author(s):  
Atanu Chandra ◽  
Shrestha Ghosh ◽  
Uddalak Chakraborty ◽  
Debojyoti Ray

Right-sided native valve infective endocarditis is common in patients with congenital or valvular heart disease, intracardiac device, central venous catheter and intravenous drug abuse, usually manifesting in adulthood. However, in the absence of predisposing risk factors and in younger age groups, this disease may pose a diagnostic challenge. We report a case series of three juvenile patients with isolated tricuspid valve infective endocarditis without any risk factors and paucity of cardiovascular findings in two of them, in an attempt to highlight the importance of maintaining a high index of suspicion to arrive a timely diagnosis.


2019 ◽  
Vol 71 (1) ◽  
pp. 80-84 ◽  
Author(s):  
Ghada S. Youssef ◽  
Marwa S. Mashaal ◽  
Dalia R. El Remisy ◽  
Khalid A. Sorour ◽  
Hussein H. Rizk

2021 ◽  
Vol 14 (4) ◽  
pp. e241264
Author(s):  
Miguel Oyonarte Gómez ◽  
Cesar Del Castillo Gordillo ◽  
Manuel Rojas Romero ◽  
Kenyin Loo Urbina

Human bites are an infrequent cause of emergency department visits and hospital admissions. There are rarely published cases of complicated infection, such as infective endocarditis. We present a rare case of a patient with acute infective endocarditis in a healthy native valve and purulent pericarditis from a human bite. A 40-year-old man with obesity suffered deep human bites by an adult woman, with two deep lesions in the anterior thorax and one superficial lesion in the upper abdomen and admitted in intensive care unit with septic shock and a persistent aortic murmur. Echocardiography described evidence of vegetation, perforation and severe regurgitation of aortic valve. Scanner described moderate pericardial effusion. Cardiac surgery was performed, with evidence of purulent pericardial effusion after pericardiotomy, and subsequently aortic valve replacement with a 25 mm bioprosthesis. The patient showed positive progress.


2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Muhannad Antoun ◽  
John Deel ◽  
Dermot Halpin ◽  
Fadi Al-Akhrass

Right-sided native valve infective endocarditis (IE) includes tricuspid valve (TV) and pulmonic valve (PV). It represents 10% of all cases. However, it is more common in persons who inject drugs or in presence of cardiac implantable electronic device (CIED). Pulmonic valve endocarditis is a rare infection and represents ∼1% of all cases. Our case represents a patient with large pulmonic valve vegetation with no known common risk factors for right-sided IE.


Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Oguzhan Kursun ◽  
Mehmet A Topcuoglu ◽  
Hulya Karatas ◽  
Ferdinando S Buonanno ◽  
Aneesh B Singhal

Background: Stroke is a common, serious complication of infective endocarditis (IE). We investigated risk factors for IE-associated cerebrovascular disease. Methods: We retrospectively reviewed data of all inpatients with discharge ICD-9 codes of IE admitted to our tertiary care hospital from 1980-2011. The diagnosis of IE was confirmed using the original Duke Criteria. Stroke was confirmed on CT or MRI. Results: Of 1151 hospitalizations (1083 adults), 277 (24%) included IE-related stroke (76% ischemic, 13% hemorrhagic, 10% both). Stroke patients had mean age 56 yrs, 63% male, 93% ’Definite IE’ per Duke Criteria, and 83% Native Valve infection. Organism types were Staph 40%, Strep 30% and Other 30%. Trans-esophageal echo was performed in 53% and MRI in 57%. The Stroke and Non-Stroke Groups showed no significant difference in age, sex, traditional cardiovascular risk factors (Htn, DM, lipids, AFib etc), and type of infectious organism. Patients with Stroke had a significantly higher frequency of multiple vegetations (20% vs 8%, p<0.001), cardiac abscess (16% vs 10%, p<0.01), cardiac surgery (37% vs 26%, p<0.01), sepsis (24% vs 14%, p<0.01) and DIC (9% vs 2%, p<0.01) and a tended to have higher rates of cardiac rupture (19% v 15%, p=0.08) and lower admission platelet counts (224 vs 249 thousand/cmm, p=0.11). The Ischemic Stroke sub-group showed similar high rates for these variables. Multivariate regression analysis showed IE-related stroke to be significantly predicted by the presence of sepsis (O.R. 3.6, 95%CI 1.8-7.0), congestive heart failure (O.R. 2.1, 95%CI 1.3-3.4), prosthetic valve IE (O.R. 2.3, 95%CI 1.13-4.4), and vegetations in aortic (OR 2.4, 95%CI 1.3-4.3) or mitral (OR 6.6, 95%CI 3.5-12.2) valves. Tricuspid vegetations (OR 0.3, 95%CI 0.1-0.7) and higher platelet counts (OR 0.99, 95%CI 0.99-1.0) had a protective effect. Age, Htn, DM, AFib, multiple vegetations, organism type, antibiotic use, and echo findings of cardiac abscess/rupture, did not predict stroke. Stroke patients had significantly worse outcomes with 22% deaths vs. 9% in non-stroke patients (p<0.001). Conclusion: This large 31-year retrospective study shows that potentially treatable conditions such as CHF and sepsis are associated with a higher rate of IE-related stroke.


2020 ◽  
Vol 21 (12) ◽  
pp. 1140-1153 ◽  
Author(s):  
Mohammad A. Noshak ◽  
Mohammad A. Rezaee ◽  
Alka Hasani ◽  
Mehdi Mirzaii

Coagulase-negative staphylococci (CoNS) are part of the microbiota of human skin and rarely linked with soft tissue infections. In recent years, CoNS species considered as one of the major nosocomial pathogens and can cause several infections such as catheter-acquired sepsis, skin infection, urinary tract infection, endophthalmitis, central nervous system shunt infection, surgical site infections, and foreign body infection. These microorganisms have a significant impact on human life and health and, as typical opportunists, cause peritonitis in individuals undergoing peritoneal dialysis. Moreover, it is revealed that these potential pathogens are mainly related to the use of indwelling or implanted in a foreign body and cause infective endocarditis (both native valve endocarditis and prosthetic valve endocarditis) in patients. In general, approximately eight percent of all cases of native valve endocarditis is associated with CoNS species, and these organisms cause death in 25% of all native valve endocarditis cases. Moreover, it is revealed that methicillin-resistant CoNS species cause 60 % of all prosthetic valve endocarditis cases. In this review, we describe the role of the CoNS species in infective endocarditis, and we explicated the reported cases of CoNS infective endocarditis in the literature from 2000 to 2020 to determine the role of CoNS in the process of infective endocarditis.


Infection ◽  
2019 ◽  
Vol 48 (1) ◽  
pp. 3-5 ◽  
Author(s):  
Hussam Eddin Talhat Al Hennawi ◽  
Elham Mohammed Mahdi ◽  
Ziad A. Memish

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