scholarly journals Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D

Biochimie ◽  
2013 ◽  
Vol 95 (7) ◽  
pp. 1379-1385 ◽  
Author(s):  
Yanfeng Zhang ◽  
Anna S. Gardberg ◽  
Thomas E. Edwards ◽  
Banumathi Sankaran ◽  
Howard Robinson ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Functional Role ◽  
Botulinum Neurotoxin ◽  
Binding Domain ◽  
Receptor Binding Domain ◽  
Structural Insights

Role of key point Mutations in Receptor Binding Domain of SARS-CoV-2 Spike Glycoprotein

2020 ◽  
Vol 20 ◽  
Author(s):  
Bipin Singh
Keyword(s):  
Receptor Binding ◽  
Point Mutations ◽  
Binding Domain ◽  
Receptor Binding Domain ◽  
Spike Glycoprotein ◽  
Angiotensin Converting Enzyme 2 ◽  
Recent Outbreak ◽  
Novel Coronavirus ◽  
Genomic Similarity

: The recent outbreak of novel coronavirus (SARS-CoV-2 or 2019-nCoV) and its worldwide spread is posing one of the major threats to human health and the world economy. It has been suggested that SARS-CoV-2 is similar to SARSCoV based on the comparison of the genome sequence. Despite the genomic similarity between SARS-CoV-2 and SARSCoV, the spike glycoprotein and receptor binding domain in SARS-CoV-2 shows the considerable difference compared to SARS-CoV, due to the presence of several point mutations. The analysis of receptor binding domain (RBD) from recently published 3D structures of spike glycoprotein of SARS-CoV-2 (Yan, R., et al. (2020); Wrapp, D., et al. (2020); Walls, A. C., et al. (2020)) highlights the contribution of a few key point mutations in RBD of spike glycoprotein and molecular basis of its efficient binding with human angiotensin-converting enzyme 2 (ACE2).

scholarly journals Botulinum Neurotoxin Devoid of Receptor Binding Domain Translocates Active Protease

2008 ◽  
Vol 4 (12) ◽  
pp. e1000245 ◽  
Author(s):  
Audrey Fischer ◽  
Darren J. Mushrush ◽  
D. Borden Lacy ◽  
Mauricio Montal
Keyword(s):  
Receptor Binding ◽  
Botulinum Neurotoxin ◽  
Binding Domain ◽  
Receptor Binding Domain ◽  
Active Protease

scholarly journals Role of phenylalanine 150 in the receptor-binding domain of the K88 fibrillar subunit.

1987 ◽  
Vol 169 (11) ◽  
pp. 4907-4911 ◽  
Author(s):  
A A Jacobs ◽  
B Roosendaal ◽  
J F van Breemen ◽  
F K de Graaf
Keyword(s):  
Receptor Binding ◽  
Binding Domain ◽  
Receptor Binding Domain

scholarly journals Structural Insights into Immune Recognition of the Severe Acute Respiratory Syndrome Coronavirus S Protein Receptor Binding Domain

2009 ◽  
Vol 388 (4) ◽  
pp. 815-823 ◽  
Author(s):  
John E. Pak ◽  
Chetna Sharon ◽  
Malathy Satkunarajah ◽  
Thierry C. Auperin ◽  
Cheryl M. Cameron ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Receptor Binding ◽  
Binding Domain ◽  
Immune Recognition ◽  
Receptor Binding Domain ◽  
S Protein ◽  
Protein Receptor ◽  
Structural Insights

scholarly journals Crystal Structure of the Receptor-Binding Domain of Botulinum Neurotoxin Type HA, Also Known as Type FA or H

Toxins ◽  
2017 ◽  
Vol 9 (3) ◽  
pp. 93 ◽  
Author(s):  
Guorui Yao ◽  
Kwok-ho Lam ◽  
Kay Perry ◽  
Jasmin Weisemann ◽  
Andreas Rummel ◽  
...  
Keyword(s):  
Crystal Structure ◽  
Receptor Binding ◽  
Botulinum Neurotoxin ◽  
Binding Domain ◽  
Receptor Binding Domain
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