A novel label-free multi-throughput optical biosensor based on localized surface plasmon resonance

2009 ◽  
Vol 24 (7) ◽  
pp. 2255-2259 ◽  
Author(s):  
Haowen Huang ◽  
Chaocai He ◽  
Yunlong Zeng ◽  
Xiaodong Xia ◽  
Xianyong Yu ◽  
...  
RSC Advances ◽  
2015 ◽  
Vol 5 (31) ◽  
pp. 23990-23998 ◽  
Author(s):  
Gaoling Liang ◽  
Zhongjun Zhao ◽  
Yin Wei ◽  
Kunping Liu ◽  
Wenqian Hou ◽  
...  

A simple, label-free and cost-effective localized surface plasmon resonance (LSPR) immunosensing method was developed for detection of alpha-fetoprotein (AFP).


2006 ◽  
Vol 915 ◽  
Author(s):  
Tomofumi Arai ◽  
Penmetcha K. R. Kumar ◽  
Koichi Awazu ◽  
Junji Tominaga

AbstractIn this paper, an optical biosensor based on the localized surface plasmon resonance (LSPR) of Ag nanostructured films is proposed and demonstrated. The Ag nanostructured films, which are fabricated by the reduction of AgOx thin films, exhibit a strong LSPR at wavelengths around 370 nm in an air environment. The reflectance spectra of the Ag nanostructured film represent that the shift in the LSPR wavelength follows a linear dependence on the refractive index of the surrounding medium. By varying the concentration of streptavidin solution, we demonstrate that the Ag nanostructured films functionalized with thiol and biotin molecules can sensitively detect a binding event between biotin and streptavidin molecules.


Sign in / Sign up

Export Citation Format

Share Document