scholarly journals Effectiveness of chronic hepatitis C treatment with direct-acting antivirals in the Public Health System in Brazil

2018 ◽  
Vol 22 (4) ◽  
pp. 317-322 ◽  
Author(s):  
Iandra Holzmann ◽  
Cristiane V. Tovo ◽  
Roseline Minmé ◽  
Mônica P. Leal ◽  
Michele P. Kliemann ◽  
...  
Keyword(s):  
Public Health ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Health System ◽  
Chronic Hepatitis C ◽  
Public Health System ◽  
Direct Acting Antivirals ◽  
Hepatitis C Treatment ◽  
The Public ◽  
Direct Acting

scholarly journals NON-ADHERENCE TO HEPATITIS C TREATMENT: A BRAZILIAN REPORT

2021 ◽  
Vol 58 (4) ◽  
pp. 456-460
Author(s):  
Claudia Alexandra Pontes IVANTES ◽  
Bernardo Carvalho da SILVA ◽  
Gabriel Gonçalves ACOSTA ◽  
Fabiane Beatriz Neves El TAWIL ◽  
Renato NISIHARA
Keyword(s):  
Public Health ◽  
Hepatitis C ◽  
Health System ◽  
Public Health System ◽  
Epidemiological Data ◽  
Hepatitis C Treatment ◽  
The Public ◽  
Direct Acting Antiviral ◽  
Private Medicine ◽  
Direct Acting

ABSTRACT BACKGROUND: In Brazil, since 2015, the treatment of hepatitis C is provided by SUS (Public Health System) with direct-acting antiviral (DAA). OBJECTIVE: To describe the rate of non-adherence patients to hepatitis C treatment by DAA, investigating the epidemiological data in a large database from Curitiba, Brazil. METHODS: Retrospective study with patients treated between January 2015 and June 2019. Patients were considered adherent when received all medication doses during their treatment. The following data were evaluated: gender, age, type of treatment, period of treatment, presence of diabetes or HIV, previous therapy, originated from SUS or private medicine, fibrosis grade and HCV genotype. RESULTS: 1248 patients (56.8% males) were studied and 102/1248 (8.2%) were non-adherent to treatment. Age or gender not influenced significantly; 10.2% patients from SUS and 3.7% individuals from private medicine were non-adherent (P<0.0001; OR=2.9; CI95%=1.6-9.1); 13.1% patients were co-infected with HIV and among them, 15.9% abandoned treatment. Individuals without co-infection presented 7.0% of non-adherence (P<0.0001; OR=2.5; CI=1.5-4.1). All the other variables showed no differences in the adhesion rate. CONCLUSION: Our study showed that 8.2% of patients were non-adherent to HCV treatment, and that patients from the Public Health System and co-infected with HIV were significantly less adherent.

Effectiveness of direct‐acting antivirals for chronic hepatitis C treatment in migrant and non‐migrant populations in France

2021 ◽  
Author(s):  
Tchadine Djaogol ◽  
Hélène Fontaine ◽  
Maël Baudoin ◽  
Camelia Protopopescu ◽  
Fabienne Marcellin ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Direct Acting Antivirals ◽  
Hepatitis C Treatment ◽  
Migrant Populations ◽  
Direct Acting

Effectiveness and safety of chronic hepatitis C treatment with direct-acting antivirals in patients with rheumatic diseases: A case-series

2019 ◽  
Vol 30 (6) ◽  
pp. 1009-1015
Author(s):  
Takashi Kida ◽  
Atsushi Umemura ◽  
Shunya Kaneshita ◽  
Risa Sagawa ◽  
Takuya Inoue ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Rheumatic Diseases ◽  
Case Series ◽  
Direct Acting Antivirals ◽  
Hepatitis C Treatment ◽  
Direct Acting

Decentralized care with generic direct-acting antivirals in the management of chronic hepatitis C in a public health care setting

2019 ◽  
Vol 71 (6) ◽  
pp. 1076-1085 ◽  
Author(s):  
Radha K. Dhiman ◽  
Gagandeep S. Grover ◽  
Madhumita Premkumar ◽  
Sunil Taneja ◽  
Ajay Duseja ◽  
...  
Keyword(s):  
Public Health ◽  
Health Care ◽  
Chronic Hepatitis ◽  
Hepatitis C ◽  
Chronic Hepatitis C ◽  
Care Setting ◽  
Public Health Care ◽  
Direct Acting Antivirals ◽  
Direct Acting ◽  
Decentralized Care
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