Identification of Hsp70 modulators through modeling of the substrate binding domain

2009 ◽  
Vol 19 (14) ◽  
pp. 3828-3831 ◽  
Author(s):  
Conor M. Haney ◽  
Corinne Schneider ◽  
Barbara Beck ◽  
Jeffrey L. Brodsky ◽  
Alexander Dömling
Keyword(s):  
Substrate Binding ◽  
Binding Domain ◽  
Substrate Binding Domain

scholarly journals Entropic Inhibition: How the Activity of a AAA+ Machine Is Modulated by Its Substrate-Binding Domain

2021 ◽  
Author(s):  
Marija Iljina ◽  
Hisham Mazal ◽  
Pierre Goloubinoff ◽  
Inbal Riven ◽  
Gilad Haran
Keyword(s):  
Substrate Binding ◽  
Binding Domain ◽  
Substrate Binding Domain

scholarly journals Flexible Linkers Leash the Substrate Binding Domain of SspB to a Peptide Module that Stabilizes Delivery Complexes with the AAA+ ClpXP Protease

2003 ◽  
Vol 12 (2) ◽  
pp. 355-363 ◽  
Author(s):  
David A Wah ◽  
Igor Levchenko ◽  
Gabrielle E Rieckhof ◽  
Daniel N Bolon ◽  
Tania A Baker ◽  
...  
Keyword(s):  
Substrate Binding ◽  
Binding Domain ◽  
Substrate Binding Domain

scholarly journals An atomistic view of Hsp70 allosteric crosstalk: from the nucleotide to the substrate binding domain and back

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Federica Chiappori ◽  
Ivan Merelli ◽  
Luciano Milanesi ◽  
Giorgio Colombo ◽  
Giulia Morra
Keyword(s):  
Substrate Binding ◽  
Binding Domain ◽  
Substrate Binding Domain

Rotary and Unidirectional Metal Shadowing of VAT: Localization of the Substrate-Binding Domain

2000 ◽  
Vol 132 (2) ◽  
pp. 162-168 ◽  
Author(s):  
Beate Rockel ◽  
Reinhard Guckenberger ◽  
Heinz Gross ◽  
Peter Tittmann ◽  
Wolfgang Baumeister
Keyword(s):  
Substrate Binding ◽  
Binding Domain ◽  
Substrate Binding Domain

Studies on the effect of the J-domain on the substrate binding domain (SBD) of Hsp70 using a chimeric human J-SBD polypeptide

2019 ◽  
Vol 124 ◽  
pp. 111-120 ◽  
Author(s):  
Ana O. Tiroli-Cepeda ◽  
Thiago V. Seraphim ◽  
Glaucia M.S. Pinheiro ◽  
Denio E.P. Souto ◽  
Lauro T. Kubota ◽  
...  
Keyword(s):  
Substrate Binding ◽  
Binding Domain ◽  
J Domain ◽  
Substrate Binding Domain

Engineering the substrate-binding domain of an esterase enhances its hydrolytic activity toward fatty acid esters

2014 ◽  
Vol 49 (12) ◽  
pp. 2101-2106 ◽  
Author(s):  
Young-A Lee ◽  
Eun-Yeong Jeon ◽  
Sun-Mee Lee ◽  
Uwe T. Bornscheuer ◽  
Jin-Byung Park
Keyword(s):  
Fatty Acid ◽  
Substrate Binding ◽  
Hydrolytic Activity ◽  
Binding Domain ◽  
Fatty Acid Esters ◽  
Substrate Binding Domain ◽  
Acid Esters

High-resolution solution structure of the 18 kDa substrate-binding domain of the mammalian chaperone protein Hsc70 1 1Edited by P. E. Wright

1999 ◽  
Vol 289 (5) ◽  
pp. 1387-1403 ◽  
Author(s):  
Robert C Morshauser ◽  
Weidong Hu ◽  
Hong Wang ◽  
Yuxi Pang ◽  
Gregory C Flynn ◽  
...  
Keyword(s):  
High Resolution ◽  
Solution Structure ◽  
Substrate Binding ◽  
Binding Domain ◽  
Chaperone Protein ◽  
Substrate Binding Domain
Sign in / Sign up

Export Citation Format

Share Document