Synthesis and pharmacological characterization of constrained analogues of Vestipitant as in vitro potent and orally active NK1 receptor antagonists

2010 ◽  
Vol 20 (2) ◽  
pp. 623-627 ◽  
Author(s):  
Fabio M. Sabbatini ◽  
Romano Di Fabio ◽  
Cristiana Griffante ◽  
Giorgio Pentassuglia ◽  
Laura Zonzini ◽  
...  
Keyword(s):  
Nk1 Receptor ◽  
Receptor Antagonists ◽  
Pharmacological Characterization ◽  
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ChemInform Abstract: Tetrazole NK1 Receptor Antagonists: The Identification of an Exceptionally Potent Orally Active Antiemetic Compound.

ChemInform ◽  
2010 ◽  
Vol 27 (36) ◽  
pp. no-no
Author(s):  
D. R. ARMOUR ◽  
K. M. L. CHUNG ◽  
M. CONGREVE ◽  
B. EVANS ◽  
S. GUNTRIP ◽  
...  
Keyword(s):  
Nk1 Receptor ◽  
Receptor Antagonists ◽  
Nk1 Receptor Antagonists ◽  
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Tetrazole NK1 receptor antagonists: The identification of an exceptionally potent orally active antiemetic compound

1996 ◽  
Vol 6 (9) ◽  
pp. 1015-1020 ◽  
Author(s):  
D.R. Armour ◽  
K.M.L. Chung ◽  
M. Congreve ◽  
B. Evans ◽  
S. Guntrip ◽  
...  
Keyword(s):  
Nk1 Receptor ◽  
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In vitro and in vivo pharmacological characterization of the novel NK1 receptor selective antagonist Netupitant

Peptides ◽  
2012 ◽  
Vol 37 (1) ◽  
pp. 86-97 ◽  
Author(s):  
Anna Rizzi ◽  
Barbara Campi ◽  
Valeria Camarda ◽  
Stefano Molinari ◽  
Sergio Cantoreggi ◽  
...  
Keyword(s):  
The Novel ◽  
Nk1 Receptor ◽  
Pharmacological Characterization ◽  
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scholarly journals Nonpeptidic urotensin-II receptor antagonists I: in vitro pharmacological characterization of SB-706375

2005 ◽  
Vol 145 (5) ◽  
pp. 620-635 ◽  
Author(s):  
Stephen A Douglas ◽  
David J Behm ◽  
Nambi V Aiyar ◽  
Diane Naselsky ◽  
Jyoti Disa ◽  
...  
Keyword(s):  
Urotensin Ii ◽  
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Pharmacological profiles of new orally active nonpeptide tachykinin NK1 receptor antagonists

1998 ◽  
Vol 341 (2-3) ◽  
pp. 235-241 ◽  
Author(s):  
Rumiko Hosoki ◽  
Mitsuhiko Yanagisawa ◽  
Yuko Onishi ◽  
Koichi Yoshioka ◽  
Masanori Otsuka
Keyword(s):  
Nk1 Receptor ◽  
Receptor Antagonists ◽  
Nk1 Receptor Antagonists ◽  
Orally Active ◽  
Pharmacological Profiles
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