Atypical myelinogenesis and reduced axon caliber in the Scn1a variant model of Dravet syndrome: An electron microscopy pilot study of the developing and mature mouse corpus callosum

2021 ◽  
Vol 1751 ◽  
pp. 147157
Author(s):  
Kay Richards ◽  
Nikola Jancovski ◽  
Eric Hanssen ◽  
Alan Connelly ◽  
Steve Petrou
Keyword(s):  
Electron Microscopy ◽  
Pilot Study ◽  
Corpus Callosum ◽  
Dravet Syndrome ◽  
Mature Mouse

scholarly journals A New Statistical Framework for Corpus Callosum Sub-Region Characterization Based on LBP Texture in Patients With Parkinsonian Disorders: A Pilot Study

2020 ◽  
Vol 14 ◽  
Author(s):  
Debanjali Bhattacharya ◽  
Neelam Sinha ◽  
Shweta Prasad ◽  
Pramod Kumar Pal ◽  
Jitender Saini ◽  
...  
Keyword(s):  
Pilot Study ◽  
Corpus Callosum ◽  
Statistical Framework ◽  
Parkinsonian Disorders

Six-Month Healing of the Nonocclusive Coronary Anastomotic Connector in an Off-Pump Porcine Bypass Model

2014 ◽  
Vol 9 (2) ◽  
pp. 130-136 ◽  
Author(s):  
David Stecher ◽  
Pierfrancesco Agostoni ◽  
Gerard Pasterkamp ◽  
Imo E. Hoefer ◽  
Lex A. van Herwerden ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Optical Coherence Tomography ◽  
Coronary Artery ◽  
Pilot Study ◽  
Internal Thoracic Artery ◽  
Artery Bypass ◽  
Optical Coherence ◽  
Off Pump ◽  
Scanning Electron

Objective This pilot study evaluates the anastomotic healing of the Excimer Laser Assisted Nonocclusive Anastomosis coronary connector at 6 months in a porcine off-pump coronary artery bypass (OPCAB) model. Methods Left internal thoracic artery to left anterior descending coronary artery bypass in two animals and left internal thoracic artery to left anterior descending coronary artery and right internal thoracic artery to right coronary artery bypasses in one animal were evaluated intraoperatively and at 6 months. The anastomoses (n = 4) were examined by angiography, intravascular ultrasound, optical coherence tomography, scanning electron microscopy, and histology. Results At follow-up, all anastomoses (n = 4) were fully patent (FitzGibbon grade A). Scanning electron microscopy demonstrated complete endothelial coverage of the anastomotic surface, and histology showed minimal streamlining intimal hyperplasia. The in vivo intravascular ultrasound and optical coherence tomography acquisitions confirmed histologic findings. Optical coherence tomography demonstrated 0.06-mm intimal coverage of the intraluminal part of the connector along the full circumference of the anastomosis. Conclusions In this pilot study, the Excimer Laser Assisted Non-occlusive Anastomosis coronary connector showed an excellent healing response on the long-term in the porcine OPCAB model. Hence, this new concept might be a potential alternative to hand-sutured anastomosis in (minimally invasive) OPCAB surgery.

scholarly journals Quantitative analysis of mouse corpus callosum from electron microscopy images

Data in Brief ◽  
2015 ◽  
Vol 5 ◽  
pp. 124-128 ◽  
Author(s):  
Kathryn L. West ◽  
Nathaniel D. Kelm ◽  
Robert P. Carson ◽  
Mark D. Does
Keyword(s):  
Electron Microscopy ◽  
Quantitative Analysis ◽  
Corpus Callosum ◽  
Microscopy Images

Microstructural Characteristics of Polyurea and Polyurethanexerogels for Concrete Confinement with FRP System

2013 ◽  
Vol 742 ◽  
pp. 237-242 ◽  
Author(s):  
Mostafa Fakharifar ◽  
Zhi Bin Lin ◽  
Cheng Lin Wu ◽  
Shruti Mahadik-Khanolkar ◽  
Nicholas Leventis ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Mechanical Properties ◽  
Pilot Study ◽  
Mechanical Behavior ◽  
Confined Concrete ◽  
Stress Strain ◽  
Microstructural Characteristics ◽  
Concrete Confinement ◽  
Energy Absorbing

Due to their exceptional mechanical properties,xerogels attract increasing attention forstructural applications. In this study, the mechanical behavior of two types of polymeric xerogelsis investigated. The excellent energy-absorbing capability of those xerogelsis demonstrated by their stress-strain relations with respect to their microstructure determined withscanning electron microscopy (SEM). A pilot study on the effects of xerogellayers in an FRP system for concrete confinementis conducted.Test results clearly indicatedthat the proposed multi-layer systemcan significantly increase the ductility of confined concrete.

Surface morphology analysis of dental implants following insertion into bone using scanning electron microscopy: a pilot study

2014 ◽  
Vol 26 (11) ◽  
pp. 1261-1266 ◽  
Author(s):  
Herbert Deppe ◽  
Christina Grünberg ◽  
Mücke Thomas ◽  
Anton Sculean ◽  
Klaus-Ulrich Benner ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Pilot Study ◽  
Surface Morphology ◽  
Dental Implants ◽  
Morphology Analysis ◽  
Scanning Electron

scholarly journals Osseointegration of a 3D Printed Stemmed Titanium Dental Implant: A Pilot Study

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
James Tedesco ◽  
Bryan E. J. Lee ◽  
Alex Y. W. Lin ◽  
Dakota M. Binkley ◽  
Kathleen H. Delaney ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Pilot Study ◽  
Dental Implant ◽  
Bone Growth ◽  
Bone Implant ◽  
Stress Cracking ◽  
Transmission Electron ◽  
Titanium Dental Implant ◽  
3D Printed

In this pilot study, a 3D printed Grade V titanium dental implant with a novel dual-stemmed design was investigated for its biocompatibility in vivo. Both dual-stemmed (n = 12) and conventional stainless steel conical (n = 4) implants were inserted into the tibial metaphysis of New Zealand white rabbits for 3 and 12 weeks and then retrieved with the surrounding bone, fixed, dehydrated, and embedded into epoxy resin. The implants were analyzed using correlative histology, microcomputed tomography, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The histological presence of multinucleated osteoclasts and cuboidal osteoblasts revealed active bone remodeling in the stemmed implant starting at 3 weeks and by 12 weeks in the conventional implant. Bone-implant contact values indicated that the stemmed implants supported bone growth along the implant from the coronal crest at both 3- and 12-week time periods and showed bone growth into microporosities of the 3D printed surface after 12 weeks. In some cases, new bone formation was noted in between the stems of the device. Conventional implants showed mechanical interlocking but did have indications of stress cracking and bone debris. This study demonstrates the comparable biocompatibility of these 3D printed stemmed implants in rabbits up to 12 weeks.

Corpus callosum thickness on mid-sagittal MRI as a marker of brain volume: a pilot study in children with HIV-related brain disease and controls

2015 ◽  
Vol 45 (7) ◽  
pp. 1016-1025 ◽  
Author(s):  
Savvas Andronikou ◽  
Christelle Ackermann ◽  
Barbara Laughton ◽  
Mark Cotton ◽  
Nicollette Tomazos ◽  
...  
Keyword(s):  
Pilot Study ◽  
Corpus Callosum ◽  
Brain Volume ◽  
Brain Disease
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