Candidemia in major burn patients and its possible risk factors: A 6-year period retrospective study at a burn ICU

Burns ◽  
2019 ◽  
Vol 45 (5) ◽  
pp. 1164-1171 ◽  
Author(s):  
Junyi Zhou ◽  
Jianglin Tan ◽  
Yali Gong ◽  
Ning Li ◽  
Gaoxing Luo
1983 ◽  
Vol 4 (S4) ◽  
pp. 325-327

Burn wounds have been classified as major or minor by various investigators according to several risk factors for burn-associated complications. We have considered only the infectious complications of burns. Therefore, we have classified major burn wounds as those that cannot effectively be covered or whose drainage cannot effectively be contained by use of dressings. The drainage from a minor burn can be covered and contained by dressings.Most major burn wounds and many minor ones have become infected by the second or third day after the burn occurs. Care of burn patients, therefore, involves efforts to prevent colonization and infection of the wound, and isolation precautions to prevent transmission to other patients. Other important methods of care include use of topical and systemic antimicrobials, vaccines, and general supportive measures.It is beyond the scope of this guideline to present comprehensive infection control recommendations for taking care of patients with burns. We have, however, made recommendations for isolation precautions for both major and minor burns infected with various pathogens. Rather than listing burn wounds separately, we have grouped them under the subheading “skin, wound, or burn infection.”


Author(s):  
Xiaoyan Cai ◽  
Zhaolin Long ◽  
Lianduo Lin ◽  
Yudong Feng ◽  
Naxi Zhou ◽  
...  

AbstractEarly detection of renal dysfunction is important in burn patients. This study evaluated whether serum cystatin C (CysC) is a potentially accurate and sensitive marker for identification of reduced glomerular filtration rate (GFR) and the risk factors of impaired renal function in major burn patients.A total of 48 adult patients with major burn injury were enrolled. Renal function was assessed using serum creatinine (sCr), 24-h urinary creatinine clearance (24-hCrCl), sCr-based formulae and CysC-based formulae on the second day and seventh day post-burn.There was a high prevalence (27.1%) of acute impaired renal function in major burn patients in the first week post-burn. CysC-based formulae for estimated GFR (eGFR) are more accurate and sensitive for detection of impaired renal function than sCr-based formulae. Multivariate logistic regression analysis demonstrated that age (OR, 2.08; 95% CI 1.26–4.77) and the percentage of burn area (OR, 3.41; 95% CI 1.64–6.95) were independent risk factors of impaired renal function.The results of this study suggest that CysC is a more accurate and sensitive marker for identification of acute impaired renal function in major burn patients than sCr. It is important to measure CysC and calculate eGFR to prevent acute renal failure and modify drug doses in burn patients, especially those of older age and with major burn areas.


Author(s):  
Atthawit Mongkornwong ◽  
Rassamee Sangthong ◽  
Surasak Sangkhathat

Objective: This study aimed to analyze the factors associated with mortality in burn patients in order to develop a nomogram for predicting mortality that can be used as a guideline to treat major burn patients.Material and Methods: This was a retrospective study done in Songhklanagarind Hospital, Hat Yai, Songkhla, Thailand. The study included major burn patients who were admitted to the burn unit or the intensive care unit between the years 2011 and 2018, and analyzed demographic data and significant factors associated with mortality.Results: A total of 127 major burn patients were treated during the study years, with a mean age of 33 years with an average total burn surface area (TBSA) of 43.5%. The most common cause of the burns was flame injury, and the most significant factors associated with mortality were TBSA >55.0%, blood creatinine >1.2 milligrams per deciliter (mg/dL) and face involvement.Conclusion: The 3 significant burn-related factors of TBSA >55.0%, blood creatinine >1.2 mg/dL and face involvement can be used to predict mortality using the nomogram created in this study.


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