Preparation and spectroscopic characterization of methoxy poly(ethylene glycol)-grafted water-soluble chitosan

2008 ◽  
Vol 343 (2) ◽  
pp. 282-289 ◽  
Author(s):  
Young-Il Jeong ◽  
Don-Gon Kim ◽  
Mi-Kyeong Jang ◽  
Jaw-Woon Nah
Keyword(s):  
Ethylene Glycol ◽  
Spectroscopic Characterization ◽  
Water Soluble ◽  
Poly Ethylene Glycol ◽  
Poly Ethylene

Poly(ethylene glycol)-Based Polymer Carrier of Doxorubicin Degradable by Both Enzymatic and Chemical Hydrolyses

2005 ◽  
Vol 70 (3) ◽  
pp. 327-338 ◽  
Author(s):  
Michal Pechar ◽  
Alena Braunová ◽  
Karel Ulbrich
Keyword(s):  
Ethylene Glycol ◽  
Water Soluble ◽  
Cancer Drug ◽  
Poly Ethylene Glycol ◽  
Polymer Carrier ◽  
Chemical Hydrolysis ◽  
Anti Cancer ◽  
Hydrazide Derivative ◽  
Poly Ethylene

The synthesis and characterization of a water-soluble biodegradable multiblock polyurethane based on poly(ethylene glycol) blocks interconnected by a pentapeptide derivative N,N'-bis(aspartylprolyl)lysine is described. The pentapeptide linkages are susceptible both to chemical hydrolysis in neutral and mild acid medium (pH 5) and to enzymatic degradation by lysosomal enzyme cathepsin B. Anti-cancer drug doxorubicin was attached to a hydrazide derivative of the polymer via a hydrolytically labile hydrazone bond. Both the pH-triggered hydrolytic release of the drug and the degradation of the polymer carrier by enzymatic and chemical hydrolysis were studied using liquid chromatography.

Synthesis and Characterization of Water Soluble Block Copolymers for pH-Sensitive Delivery

2000 ◽  
Vol 662 ◽  
Author(s):  
Brian C. Anderson ◽  
Paul D. Bloom ◽  
Valerie V. Sheares ◽  
Surya K. Mallapragada
Keyword(s):  
Block Copolymer ◽  
Ethylene Glycol ◽  
Acid Group ◽  
Water Soluble ◽  
Poly Ethylene Glycol ◽  
Release Studies ◽  
Poly Ethylene ◽  
Glycol Methyl Ether ◽  
Ab Block Copolymer

AbstractA novel, water-soluble AB-block copolymer of diethylaminoethyl methacrylate (DEAEM) and poly(ethylene glycol) (PEG) was synthesized by anionic polymerization. Poly(ethylene glycol) methyl ether (PEGME) was converted into the corresponding potassium salt by reacting with potassium metal. The PEG salt was used as a macroinitiator for the polymerization of DEAEM to yield a PEG-b-PDEAEM block copolymer. Carbon dioxide was used to terminate DEAEM polymerization with a carboxylic acid group. This polymer, loaded with dye, was tested for pH sensitivity by release studies into solutions of various pH.

Preparation and characterization of poly (ethylene glycol) grafted Ca-alginate fibers by γ-irradiation for biomedical applications

2013 ◽  
Vol 27 (2) ◽  
pp. 216-226 ◽  
Author(s):  
Md. Kamal Khan ◽  
Mohammed Mizanur Rahman ◽  
Bodrun Nesa ◽  
Romana Nasrin ◽  
Swajal Molla ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Biomedical Applications ◽  
Poly Ethylene Glycol ◽  
Γ Irradiation ◽  
Alginate Fibers ◽  
Poly Ethylene ◽  
Ca Alginate

AB2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol) and its electrospun nanofiber blend with poly(ε-caprolactone)

RSC Advances ◽  
2015 ◽  
Vol 5 (46) ◽  
pp. 36715-36726 ◽  
Author(s):  
Bakhshali Massoumi ◽  
Somayeh Davtalab ◽  
Mehdi Jaymand ◽  
Ali Akbar Entezami
Keyword(s):  
Ethylene Glycol ◽  
Electrospun Nanofibers ◽  
Synthesis And Characterization ◽  
Electrospun Nanofiber ◽  
Poly Ethylene Glycol ◽  
Conductive Polyaniline ◽  
Miktoarm Star ◽  
Poly Ethylene ◽  
Type Ab

The aim of this study is the synthesis, and characterization of novel type AB2 Y-shaped miktoarm star conductive polyaniline-modified poly(ethylene glycol), and preparation of its electrospun nanofibers blend with poly(ε-caprolactone).

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