Matrix metalloproteinase-1 promoter is associated with body mass index in Korean population with aged greater or equal to 50 years

2008 ◽  
Vol 396 (1-2) ◽  
pp. 14-17 ◽  
Author(s):  
Young-Kyun Nho ◽  
Eunyoung Ha ◽  
Kyung-Im Yu ◽  
Joo-Ho Chung ◽  
Nam-Chang Wook ◽  
...  
PLoS ONE ◽  
2017 ◽  
Vol 12 (9) ◽  
pp. e0185024 ◽  
Author(s):  
Kyoung Ae Kong ◽  
Junbeom Park ◽  
So-hyeon Hong ◽  
Young Sun Hong ◽  
Yeon-Ah Sung ◽  
...  

Author(s):  
Angel Mercy Sylus ◽  
Hanumanthappa Nandeesha ◽  
Thiagaraju Chitra

Background: Obesity, inflammation and alterations in matrix metalloproteinase-9 (MMP-9) and nitric oxide (NO) levels are involved in the development of polycystic ovary syndrome (PCOS). Objective: To investigate the relationship of MMP-9, NO and interleukin-10 (IL-10) with the increase in body mass index (BMI) in women with PCOS. Materials and Methods: Sixty two infertile PCOS women were included in the study. Serum levels of NO, IL-10 and MMP-9 were assessed in the women with increase in BMI. Results: MMP-9 was significantly increased (p = 0.029) and IL-10 (p = 0.015) was significantly reduced in obese PCOS subjects compared to those with lesser BMI. MMP- 9 levels positively correlated with the duration of infertility (r = 0.253, p = 0.047) and negatively correlated with NO levels (r = - 0.259, p = 0.042). A significant negative correlation between the interleukin-10 levels and the BMI (r = - 0.272, p = 0.033) was also found in the PCOS subjects. Conclusion: MMP-9 levels are increased in obese PCOS women and it is associated with NO levels and the duration of infertility. Key words: Body mass index, Interleukin-10, Nitric oxide, Matrix metalloproteinase-9.


PLoS ONE ◽  
2020 ◽  
Vol 15 (8) ◽  
pp. e0219647
Author(s):  
Eun-Seok Sung ◽  
Chang Kyun Choi ◽  
Ji-An Jeong ◽  
Min-Ho Shin

Endocrine ◽  
2013 ◽  
Vol 44 (3) ◽  
pp. 675-679 ◽  
Author(s):  
Jae Woong Sull ◽  
Myoungsook Lee ◽  
Sun Ha Jee

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e90516 ◽  
Author(s):  
Unjin Shim ◽  
Han-Na Kim ◽  
Seung-Ju Roh ◽  
Nam H. Cho ◽  
Chol Shin ◽  
...  

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