Synergistic effect of plant extract coupled silver nanoparticles in various therapeutic applications- present insights and bottlenecks

Chemosphere ◽  
2022 ◽  
Vol 288 ◽  
pp. 132527
Author(s):  
Mahak Majeed ◽  
Khalid Rehman Hakeem ◽  
Reiaz Ul Rehman
2020 ◽  
Vol 21 (11) ◽  
pp. 1129-1137 ◽  
Author(s):  
Somayeh Mirsadeghi ◽  
Masoumeh F. Koudehi ◽  
Hamid R. Rajabi ◽  
Seied M. Pourmortazavi

Background: Herein, we report the biosynthesis procedure to prepare silver nanoparticles as reduction and capping agents with the aqueous plant extract of Perovskia abrotanoides. Methods: The therapeutic application of silver nanoparticles entirely depends on the size and shape of the nanoparticles therefore, their control during the synthesis procedure is so important. The effects of synthesis factors, for example, silver ion concentration, the mass of plant extract, reaction time and extraction temperature, on the size of silver particles were considered and optimized. Several analytical methods were used for the characterization of silver NPs including FT-IR and UV–Vis spectrophotometer, XRD and SEM. Results: The results showed that the mean size of the silver particles was about 51 nm. Moreover, the antibacterial properties of biosynthesized silver NPs were investigated by the minimum inhibitory concentration, minimum bactericidal concentration, and Well-diffusion tests. The minimum inhibitory concentration/ minimum bactericidal concentration values of silver NPs and aqueous plant extract versus Gram-positive bacteria (Staphylococcus aureus and Bacillus cereus) and Gram-negative bacteria (E. coli) were 3.03/0.00, 1.20/0.01, 3.06/0.00, 0.98/1.04, 1.00/0.05 and 1.30/0.03 (mg/mL), respectively. Conclusion: The antimicrobial activity study displayed that the synthesized silver nanoparticles by plant extract have better antimicrobial properties compared to aqueous plant extract of Perovskia abrotanoides.


2015 ◽  
Vol 70 ◽  
pp. 356-373 ◽  
Author(s):  
Ramachandran Rajan ◽  
Krishnaraj Chandran ◽  
Stacey L. Harper ◽  
Soon-Il Yun ◽  
P. Thangavel Kalaichelvan

2021 ◽  
Vol 138 ◽  
pp. 106850
Author(s):  
A.S. Nikolov ◽  
N.E. Stankova ◽  
D.B. Karashanova ◽  
N.N. Nedyalkov ◽  
E.L. Pavlov ◽  
...  

2017 ◽  
Vol 6 (5) ◽  
Author(s):  
Zahra Abbasi ◽  
Sholeh Feizi ◽  
Elham Taghipour ◽  
Parinaz Ghadam

AbstractSilver nanoparticles (AgNPs) have widespread applications. Recently, the synthesis of NPs using plant extract has attracted much attention. In this study, with an easy and rapid process at room temperature, AgNPs were produced by the aqueous extract of dried


2021 ◽  
Author(s):  
Guofeng Su ◽  
Ximing Zhong ◽  
Songfa Qiu ◽  
Jiajin Fan ◽  
hongjun zhou ◽  
...  

Abstract In this work, a novel antibacterial nanocomposite system was developed using mesoporous silica (MSN) as an effective nanocarrier, and the resultant nanocomposites demonstrated remarkable antibacterial performance due to the synergistic effect among nano zinc oxides, silver nanoparticles, and polydopamine (PDA). The successful synthesis of MSN/ZnO@PDA/Ag nanocomposites was confirmed. The physicochemical properties and the morphologies of these nanocomposites were investigated. It was found that the particle size increased along with the evolution of these nanocomposites. Besides, nano zinc oxides were formed in the nanoconfinement channel of mesoporous silica with a particle size about 2 nm, and that of silver nanoparticle was less than 50 nm. In addition, the results revealed that the presence of mesoporous silica could effectively prevent the formation of large-size silver nanoparticles and facilitate their well dispersion. Due to the synergistic effect among nano zinc oxides, silver nanoparticles, and polydopamine, these nanocomposites exhibited remarkable antibacterial performance even at a low concentration of 313 ppm, and the antibacterial mechanism was also elucidated. Therefore, this work provides a facile and controllable approach to preparing synergistically antibacterial nanocomposites, and the remarkable antibacterial performance make them suitable for practical applications.


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