scholarly journals Genomics of Blood Pressure and Hypertension: Extending the Mosaic Theory Toward Stratification

2020 ◽  
Vol 36 (5) ◽  
pp. 694-705 ◽  
Author(s):  
Stefanie Lip ◽  
Sandosh Padmanabhan
Keyword(s):  
Blood Pressure ◽  
Mosaic Theory

Pathophysiology of Hypertension

2021 ◽  
Vol 128 (7) ◽  
pp. 847-863 ◽  
Author(s):  
David G. Harrison ◽  
Thomas M. Coffman ◽  
Christopher S. Wilcox
Keyword(s):  
Oxidative Stress ◽  
Blood Pressure ◽  
Organ Damage ◽  
Experimental Models ◽  
Sodium Homeostasis ◽  
Circulation Research ◽  
Raise Blood Pressure ◽  
New Concepts ◽  
Constant Feature ◽  
Mosaic Theory

Dr Irvine Page proposed the Mosaic Theory of Hypertension in the 1940s advocating that hypertension is the result of many factors that interact to raise blood pressure and cause end-organ damage. Over the years, Dr Page modified his paradigm, and new concepts regarding oxidative stress, inflammation, genetics, sodium homeostasis, and the microbiome have arisen that allow further refinements of the Mosaic Theory. A constant feature of this approach to understanding hypertension is that the various nodes are interdependent and that these almost certainly vary between experimental models and between individuals with hypertension. This review discusses these new concepts and provides an introduction to other reviews in this compendium of Circulation Research .

Interrelations between various blood pressure regulatory systems and the mosaic theory of hypertension

1979 ◽  
Vol 28 (19) ◽  
pp. 2867-2882 ◽  
Author(s):  
Mahesh C. Khosla ◽  
Irvine H. Page ◽  
F.Merlin Bumpus
Keyword(s):  
Blood Pressure ◽  
Regulatory Systems ◽  
Mosaic Theory

Evaluation of two methods of teaching blood pressure measurement

1988 ◽  
Vol 52 (9) ◽  
pp. 519-521
Author(s):  
NK Nordstrom ◽  
S Longenecker ◽  
HL Whitacre ◽  
FM Beck
Keyword(s):  
Blood Pressure ◽  
Pressure Measurement ◽  
Blood Pressure Measurement

Long- and short-term blood pressure andRR-interval variability and psychosomatic distress in chronic fatigue syndrome: authors’ reply 1

1999 ◽  
Vol 97 (3) ◽  
pp. 319 ◽  
Author(s):  
D.A. DUPREZ ◽  
M.L. DE BUYZERE ◽  
B. DRIEGHE ◽  
F. VANHAVERBEKE ◽  
Y. TAES ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Fatigue Syndrome ◽  
Chronic Fatigue ◽  
Short Term ◽  
Fatigue Syndrome
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