Non-magnetic shell coating of magnetic nanoparticles as key factor of toxicity for cancer cells in a low frequency alternating magnetic field

2021 ◽  
pp. 111931
Author(s):  
A.R. Iliasov ◽  
T.R. Nizamov ◽  
V.A. Naumenko ◽  
A.S. Garanina ◽  
S.S. Vodopyanov ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Cancer Cells ◽  
Low Frequency ◽  
Alternating Magnetic Field ◽  
Key Factor ◽  
Magnetic Shell

scholarly journals In Vivo Cancer Cells Elimination Guided by Aptamer-Functionalized Gold-Coated Magnetic Nanoparticles and Controlled with Low Frequency Alternating Magnetic Field

Theranostics ◽  
2017 ◽  
Vol 7 (13) ◽  
pp. 3326-3337 ◽  
Author(s):  
Irina V. Belyanina ◽  
Tatiana N. Zamay ◽  
Galina S. Zamay ◽  
Sergey S. Zamay ◽  
Olga S. Kolovskaya ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Cancer Cells ◽  
Low Frequency ◽  
Alternating Magnetic Field

scholarly journals Magnetic nanoparticle-conjugated polymeric micelles for combined hyperthermia and chemotherapy

Nanoscale ◽  
2015 ◽  
Vol 7 (39) ◽  
pp. 16470-16480 ◽  
Author(s):  
Hyun-Chul Kim ◽  
Eunjoo Kim ◽  
Sang Won Jeong ◽  
Tae-Lin Ha ◽  
Sang-Im Park ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Synergistic Effect ◽  
Cancer Cells ◽  
Anticancer Drug ◽  
Magnetic Nanoparticle ◽  
Polymeric Micelles ◽  
Alternating Magnetic Field ◽  
Rapid Release

The cytotoxicity of magnetic nanoparticles-conjugated polymeric micelles encapsulated with an anticancer drug on cancer cells was enhanced by the synergistic effect of heat and the rapid release of the drug under an alternating magnetic field.

INCLUSION OF MAGNETIC NANOPARTICLES ОF MAGNETITE INTO PROTEIN PARTICLES OF CATALASE

2020 ◽  
pp. 83-84
Author(s):  
N. Balabushevich ◽  
K. Vlasova ◽  
D. Volodkin ◽  
Yu. Golovin ◽  
N. Klyachko
Keyword(s):  
Magnetic Field ◽  
Enzyme Activity ◽  
Magnetic Nanoparticles ◽  
Low Frequency ◽  
Alternating Magnetic Field ◽  
Precipitation Method ◽  
Immobilized Catalase ◽  
Protein Particles ◽  
Co Precipitation

In this work, vaterite microparticles with an immobilized catalase (enzyme) and magnetic nanoparticles (MNPs) of magnetite, obtained by the co-precipitation method, were used to study the enzyme activity under low frequency alternating magnetic field.

scholarly journals Non-Heating Alternating Magnetic Field Nanomechanical Stimulation of Biomolecule Structures via Magnetic Nanoparticles as the Basis for Future Low-Toxic Biomedical Applications

Nanomaterials ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2255
Author(s):  
Yuri I. Golovin ◽  
Dmitry Yu. Golovin ◽  
Ksenia Yu. Vlasova ◽  
Maxim M. Veselov ◽  
Azizbek D. Usvaliev ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Biomedical Applications ◽  
Biomedical Application ◽  
Low Frequency ◽  
Alternating Magnetic Field ◽  
Cell Organelles ◽  
Transport Vesicles ◽  
Functionalized Magnetic Nanoparticles ◽  
Enzyme Molecules

The review discusses the theoretical, experimental and toxicological aspects of the prospective biomedical application of functionalized magnetic nanoparticles (MNPs) activated by a low frequency non-heating alternating magnetic field (AMF). In this approach, known as nano-magnetomechanical activation (NMMA), the MNPs are used as mediators that localize and apply force to such target biomolecular structures as enzyme molecules, transport vesicles, cell organelles, etc., without significant heating. It is shown that NMMA can become a biophysical platform for a family of therapy methods including the addressed delivery and controlled release of therapeutic agents from transport nanomodules, as well as selective molecular nanoscale localized drugless nanomechanical impacts. It is characterized by low system biochemical and electromagnetic toxicity. A technique of 3D scanning of the NMMA region with the size of several mm to several cm over object internals has been described.

Phase-change material filled hollow magnetic nanoparticles for cancer therapy and dual modal bioimaging

Nanoscale ◽  
2015 ◽  
Vol 7 (19) ◽  
pp. 9004-9012 ◽  
Author(s):  
Jinghua Li ◽  
Yan Hu ◽  
Yanhua Hou ◽  
Xinkun Shen ◽  
Gaoqiang Xu ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Magnetic Nanoparticles ◽  
Cancer Therapy ◽  
Phase Change ◽  
Phase Change Material ◽  
Alternating Magnetic Field ◽  
Change Material

An alternating magnetic field triggered nanocarrier for drug delivery is fabricated for dual modal imaging-guided thermo-chemo cancer therapy.

In vivoheating of magnetic nanoparticles in alternating magnetic field

2004 ◽  
Vol 31 (8) ◽  
pp. 2219-2221 ◽  
Author(s):  
M. Babincová ◽  
V. Altanerová ◽  
Č. Altaner ◽  
P. Čičmanec ◽  
P. Babinec
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Alternating Magnetic Field

Extremely low frequency alternating magnetic field–triggered and MRI–traced drug delivery by optimized magnetic zeolitic imidazolate framework-90 nanoparticles

Nanoscale ◽  
2016 ◽  
Vol 8 (6) ◽  
pp. 3259-3263 ◽  
Author(s):  
Jie Fang ◽  
Yong Yang ◽  
Wen Xiao ◽  
Bingwen Zheng ◽  
Yun-Bo Lv ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Drug Delivery ◽  
Drug Release ◽  
Low Frequency ◽  
Alternating Magnetic Field ◽  
Zeolitic Imidazolate Framework ◽  
Extremely Low Frequency

An extremely low frequency alternating magnetic field of 20 Hz was proved to be able to remarkably accelerate the drug release from optimized ZIF-90 nanospheres with incorporated Fe3O4 nanoparticles acting as actuator.

scholarly journals Control the Functionality of Thermoresponsive Enzymes Immobilized onto Magnetic Nanoparticles by the Application of Alternating Magnetic Field

2014 ◽  
Vol 38 (3-1) ◽  
pp. 98-101 ◽  
Author(s):  
Satoshi Seino ◽  
Kazunari Yoshida ◽  
Toshihiro Shikakura ◽  
Kazuma Watanabe ◽  
Yuichi Koga ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Magnetic Nanoparticles ◽  
Alternating Magnetic Field
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