Simultaneous fitting of Bayesian penalised quantile splines

2019 ◽  
Vol 134 ◽  
pp. 93-109 ◽  
Author(s):  
T. Rodrigues ◽  
J.-L. Dortet-Bernadet ◽  
Y. Fan
Keyword(s):  
Simultaneous Fitting

Parameterization of multiple Bragg curves for scanning proton beams using simultaneous fitting of multiple curves

2011 ◽  
Vol 56 (24) ◽  
pp. 7725-7735 ◽  
Author(s):  
Xiaodong Zhang ◽  
Wei Liu ◽  
Yupeng Li ◽  
Xiaoqiang Li ◽  
Michelle Quan ◽  
...  
Keyword(s):  
Proton Beams ◽  
Simultaneous Fitting

Simultaneous fitting of Mars Mössbauer data

2008 ◽  
Vol 188 (1-3) ◽  
pp. 113-120 ◽  
Author(s):  
David G. Agresti ◽  
Perry A. Gerakines
Keyword(s):  
Simultaneous Fitting ◽  
Mössbauer Data

Interplay between spin crossover and exchange interaction in iron(III) complexes

2009 ◽  
Vol 81 (8) ◽  
pp. 1357-1383 ◽  
Author(s):  
Roman Boča ◽  
Ivan Nemec ◽  
Ivan Šalitroš ◽  
Ján Pavlik ◽  
Radovan Herchel ◽  
...  
Keyword(s):  
Experimental Data ◽  
Magnetic Susceptibility ◽  
Exchange Interaction ◽  
Spin Crossover ◽  
Magnetic Measurements ◽  
Spin States ◽  
Magnetic Exchange Interaction ◽  
Magnetic Exchange ◽  
Simultaneous Fitting ◽  
Polynuclear Metal Complexes

In the dinuclear and polynuclear metal complexes exhibiting the low-spin (LS) to high-spin (HS) transition, the spin-crossover phenomenon interferes with the magnetic exchange interaction. The latter manifests itself in forming spin-multiplets, which causes a possible overlap of the band originating in different reference spin states (LL, LH, HL, and HH). A series of dinuclear Fe(III) complexes has been prepared; the iron centers are linked by a bidentate bridge (CN-, and diamagnetic metallacyanates {Fe(CN)5(NO)}, {Ni(CN)4}, {Pt(CN)4}, and {Ag(CN)2}). Magnetic measurements confirm that the spin crossover proceeds on the thermal propagation. This information has been completed also by the Mössbauer spectral (MS) data. A theoretical model has been developed that allows a simultaneous fitting of all available experimental data (magnetic susceptibility, magnetization, HS mole fraction) on a common set of parameters.

Abstract 2238: New Pharmacokinetic Models for Quantitative Molecular Imaging of Plaque Angiogenesis with Intergrin-targeted Nanoparticles

Circulation ◽  
2008 ◽  
Vol 118 (suppl_18) ◽  
Author(s):  
Hoon Sim ◽  
Anne Neubauer ◽  
Shelton Caruthers ◽  
Gregory Lanza ◽  
Samuel Wickline ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Early Detection ◽  
Cross Sections ◽  
Aortic Wall ◽  
Spin Echo ◽  
Vasa Vasorum ◽  
Pharmacokinetic Models ◽  
Descending Thoracic Aorta ◽  
Targeted Nanoparticles ◽  
Simultaneous Fitting

Cardiovascular molecular imaging with targeted nanoparticles has emerged as a promising method for early detection of atherosclerosis and vulnerable plaque. However, traditional pharmacokinetic models for diffusible drugs are inadequate to describe the efficacy of nanoparticle carriers of diagnostic and therapeutic cargos. To quantify blood and MRI tissue signals from gadolinium-loaded nanoparticles (Gd-NP) targeted to avb3 integrins expressed on angiogenic capillaries in the aortas of cholesterol-fed rabbit, a novel 4 compartment open PK model was developed that utilized a unique simultaneous fitting scheme. In 10 rabbits fed 0.25% cholesterol for 3 months, the concentration of nanoparticles was measured serially from blood samples after injection of 1 ml/kg of targeted or nontargeted Gd-NP. The MRI proton signatures emanating from nanoparticles bound to the expanded vasa vasorum of the descending thoracic aorta was computed for all aortic cross sections in 1.5T T1w fa-suppressed spin-echo images. Based on the PK analysis, the concentration of targeted nanoparticles in the aortic wall is double that of non-targeted nanoparticles. Notably, this signal enhancement is achieved with 20x less gadolinium (4.6x10 −3 mmol Gd/kg BW) as compared with the dose of conventional gadolinium agents (0.1 mmol/kg). Further, the PK analysis shows that the targeted nanoparticles are more than three times more effective at reaching the aortic wall. These results should facilitate development and use of nanotechnologies intended for early detection of atherosclerosis and provide enhanced understanding of the kinetics and mechanisms of active targeting of plaque angiogenesis.

Power-law correlations, related models for long-range dependence and their simulation

2000 ◽  
Vol 37 (04) ◽  
pp. 1104-1109 ◽  
Author(s):  
Tilmann Gneiting
Keyword(s):  
Long Range ◽  
Power Law ◽  
Long Memory ◽  
Stationary Time Series ◽  
Long Range Dependence ◽  
Short Term ◽  
Permissible Range ◽  
Simultaneous Fitting ◽  
Straightforward Proof

Martin and Walker ((1997) J. Appl. Prob. 34, 657–670) proposed the power-law ρ(v) = c|v|-β, |v| ≥ 1, as a correlation model for stationary time series with long-memory dependence. A straightforward proof of their conjecture on the permissible range of c is given, and various other models for long-range dependence are discussed. In particular, the Cauchy family ρ(v) = (1 + |v/c|α)-β/α allows for the simultaneous fitting of both the long-term and short-term correlation structure within a simple analytical model. The note closes with hints at the fast and exact simulation of fractional Gaussian noise and related processes.

scholarly journals The Clover Leaf Quasar H1413+117: New Photometric Light Curves

1996 ◽  
Vol 173 ◽  
pp. 261-262 ◽  
Author(s):  
M. Remy ◽  
E. Gosset ◽  
D. Hutsemékers ◽  
B. Revenaz ◽  
J. Surdej
Keyword(s):  
General Trend ◽  
Light Curves ◽  
The Other ◽  
Comparison Star ◽  
Simultaneous Fitting

Direct CCD images of the gravitationally lensed BAL quasar H1413+117 (Bessel B, V, R, I; Gunn r and i), obtained during 1989-1994 in the framework of photometric monitorings at ESO and with the NOT, have been carefully (re-)analyzed. Simultaneous fitting of 4 PSFs, fixing the relative positions of components B, C and D with respect to A, has been achieved successfully. The relative light curves of the 4 lensed QSO images, with respect to a stable nearby comparison star, confirm the general trend already presented by Arnould et al. (1993). The amplitude of the light curves is found to be about 0.5 magnitude, peak-to-peak in the V filter. The four lensed components display brightness variations quasi-simultaneously and in parallel. In addition to these intrinsic light variations due to the source, we find that component D shows extra light variations with respect to the other components. These are very likely caused by micro-lensing.

scholarly journals Simultaneous fitting of genomic-BLUP and Bayes-C components in a genomic prediction model

2017 ◽  
Vol 49 (1) ◽  
Author(s):  
Oscar O. M. Iheshiulor ◽  
John A. Woolliams ◽  
Morten Svendsen ◽  
Trygve Solberg ◽  
Theo H. E. Meuwissen
Keyword(s):  
Prediction Model ◽  
Genomic Prediction ◽  
Simultaneous Fitting
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