Plasmid evolution

2020 ◽  
Vol 30 (19) ◽  
pp. R1158-R1163
Author(s):  
Tanita Wein ◽  
Tal Dagan
Keyword(s):  
Plasmid Evolution

Sequence of the iaa and ipt region of different Agrobacterium tumefaciens biotype III octopine strains: reconstruction of octopine Ti plasmid evolution

1991 ◽  
Vol 16 (4) ◽  
pp. 601-614 ◽  
Author(s):  
Francois Paulus ◽  
Jean Canaday ◽  
Florence Vincent ◽  
G�raldine Bonnard ◽  
Christa Kares ◽  
...  
Keyword(s):  
Agrobacterium Tumefaciens ◽  
Ti Plasmid ◽  
Plasmid Evolution

Transposable genetic elements and plasmid evolution

Nature ◽  
1976 ◽  
Vol 263 (5580) ◽  
pp. 731-734 ◽  
Author(s):  
Stanley N. Cohen
Keyword(s):  
Plasmid Evolution ◽  
Genetic Elements ◽  
Transposable Genetic Elements

scholarly journals Species and Incompatibility Determination within the P1par Family of Plasmid Partition Elements

2005 ◽  
Vol 187 (17) ◽  
pp. 5977-5983 ◽  
Author(s):  
Alena Dabrazhynetskaya ◽  
Kirill Sergueev ◽  
Stuart Austin
Keyword(s):  
Escherichia Coli ◽  
Point Mutation ◽  
Distinct Species ◽  
Base Change ◽  
Species Specificity ◽  
Site Specificity ◽  
Carboxy Terminus ◽  
Plasmid Evolution ◽  
Par Proteins ◽  
Plasmid Partition

ABSTRACT The P1par family of active plasmid partition systems consists of at least six members, broadly distributed in a variety of plasmid types and bacterial genera. Each encodes two Par proteins and contains a cis-acting parS site. Individual par systems can show distinct species specificities; the proteins from one type cannot function with the parS site of another. P1par-versus-P7par specificity resides within two hexamer BoxB repeats encoded by parS that contact the ParB protein near the carboxy terminus. Here, we examine the species specificity differences between Yersinia pestis pMT1parS and Escherichia coli P1 and P7parS. pMT1parS site specificity could be altered to that of either P1 or P7 by point mutation changes in the BoxB repeats. Just one base change in a single BoxB repeat sometimes sufficed. The BoxB sequence appears to be able to adopt a number of forms that define exclusive interactions with different ParB species. The looped parS structure may facilitate this repertoire of interaction specificities. Different P1par family members have different partition-mediated incompatibility specificities. This property defines whether two related plasmids can coexist in the same cell and is important in promoting the evolution of new plasmid species. BoxB sequence changes that switch species specificity between P1, P7, and pMT1 species switched partition-mediated plasmid incompatibility in concert. Thus, there is a direct mechanistic link between species specificity and partition-mediated incompatibility, and the BoxB-ParB interaction can be regarded as a special mechanism for facilitating plasmid evolution.

scholarly journals ISCR Elements Are Key Players in IncA/C Plasmid Evolution

2010 ◽  
Vol 54 (8) ◽  
pp. 3534-3534 ◽  
Author(s):  
M. A. Toleman ◽  
T. R. Walsh ◽  
D. R. Call
Keyword(s):  
Plasmid Evolution ◽  
Key Players

scholarly journals Complete sequences of IncHI1 plasmids carrying blaCTX-M-1 and qnrS1 in equine Escherichia coli provide new insights into plasmid evolution

2014 ◽  
Vol 69 (9) ◽  
pp. 2388-2393 ◽  
Author(s):  
Monika Dolejska ◽  
Laura Villa ◽  
Marco Minoia ◽  
Luca Guardabassi ◽  
Alessandra Carattoli
Keyword(s):  
Escherichia Coli ◽  
Plasmid Evolution ◽  
Complete Sequences

Plasmid evolution in carbapenemase‐producing Enterobacteriaceae : a review

2019 ◽  
Vol 1457 (1) ◽  
pp. 61-91 ◽  
Author(s):  
Katlego Kopotsa ◽  
John Osei Sekyere ◽  
Nontombi Marylucy Mbelle
Keyword(s):  
Plasmid Evolution

scholarly journals Functional Identification and Evolutionary Analysis of Two Novel Plasmids Mediating Quinolone Resistance in Proteus vulgaris

2020 ◽  
Vol 8 (7) ◽  
pp. 1074 ◽  
Author(s):  
Hongyang Zhang ◽  
Mingding Chang ◽  
Xiaochen Zhang ◽  
Peiyan Cai ◽  
Yixin Dai ◽  
...  
Keyword(s):  
Antibiotic Resistance Genes ◽  
Normal Function ◽  
Quinolone Resistance ◽  
Evolutionary Analysis ◽  
Proteus Vulgaris ◽  
Functional Identification ◽  
Sequence Alignments ◽  
Plasmid Evolution ◽  
Plasmid Recombination ◽  
Ciprofloxacin Resistance

Plasmid-mediated quinolone resistance (PMQR) remains one of the main mechanisms of bacterial quinolone resistance and plays an important role in the transmission of antibiotic resistance genes (ARGs). In this study, two novel plasmids, p3M-2A and p3M-2B, which mediate quinolone resistance in Proteus vulgaris strain 3M (P3M) were identified. Of these, only p3M-2B appeared to be a qnrD-carrying plasmid. Both p3M-2A and p3M-2B could be transferred into Escherichia coli, and the latter caused a twofold change in ciprofloxacin resistance, according to the measured minimum inhibitory concentration (MIC). Plasmid curing/complementation and qRT-PCR results showed that p3M-2A can directly regulate the expression of qnrD in p3M-2B under treatment with ciprofloxacin, in which process, ORF1 was found to play an important role. Sequence alignments and phylogenetic analysis revealed the evolutionary relationships of all reported qnrD-carrying plasmids and showed that ORF1–4 in p3M-2B is the most conserved backbone for the normal function of qnrD-carrying plasmids. The identified direct repeats (DR) suggested that, from an evolutionary perspective, p3M-2B may have originated from the 2683-bp qnrD-carrying plasmid and may increase the possibility of plasmid recombination and then of qnrD transfer. To the best of our knowledge, this is the first identification of a novel qnrD-carrying plasmid isolated from a P. vulgaris strain of shrimp origin and a plasmid that plays a regulatory role in qnrD expression. This study also sheds new light on plasmid evolution and on the mechanism of horizontal transfer of ARGs encoded by plasmids.

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