Screen printed diamond electrode as efficient “point-of-care” platform for submicromolar determination of cytostatic drug in biological fluids and pharmaceutical product

2021 ◽  
Vol 113 ◽  
pp. 108277
Author(s):  
Dalibor M. Stanković ◽  
Zorana Milanović ◽  
Ľubomír Švorc ◽  
Vesna Stanković ◽  
Drina Janković ◽  
...  
Keyword(s):  
Biological Fluids ◽  
Point Of Care ◽  
Pharmaceutical Product ◽  
Cytostatic Drug ◽  
Efficient Point ◽  
Diamond Electrode ◽  
Screen Printed

Disposable screen-printed chemiluminescent biochips for the simultaneous determination of four point-of-care relevant proteins

2008 ◽  
Vol 393 (4) ◽  
pp. 1191-1198 ◽  
Author(s):  
C. A. Marquette ◽  
F. Bouteille ◽  
B. P. Corgier ◽  
A. Degiuli ◽  
L. J. Blum
Keyword(s):  
Simultaneous Determination ◽  
Point Of Care ◽  
Screen Printed

scholarly journals Cost-Effective Potentiometric Platforms Modified with Multi-Walled Carbon Nanotubes (MWCNTs) and Based on Imprinted Receptors for Fluvoxamine Assessment

Polymers ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 673
Author(s):  
Heba M. Hashem ◽  
Saad S. M. Hassan ◽  
Ayman H. Kamel ◽  
Abd El-Galil E. Amr ◽  
E. M. AbdelBary
Keyword(s):  
Carbon Nanotubes ◽  
Electrochemical Impedance ◽  
Biological Fluids ◽  
Pharmaceutical Preparations ◽  
Cost Effective ◽  
Hplc Method ◽  
Multi Walled Carbon Nanotubes ◽  
Walled Carbon Nanotubes ◽  
Screen Printed

A simple, efficient and reliable analytical method was developed and used for the determination of the fluvoxamine drug (FLV) in pharmaceutical preparations and biological fluids. The method is based on the cost-effective screen-printed platform for the potential transduction of the drug. Host-tailored molecular imprinting polymer (MIP) was integrated with the potentiometric platform as a recognition receptor, in which FLV, acrylamide (AAm), ethylene glycol dimethacrylate (EGDMA) and acetonitrile were used as a template, functional monomer, cross-linker, and solvent, respectively. MIP particles were dispersed in plasticized poly (vinyl chloride) (PVC) and the membrane was drop-casted on carbon screen-printed electrode. The MIP, in addition to non-imprinted polymers (NIP), was characterized and the binding experiment revealed high affinity and adsorption capacity of MIP towards FLV. The proposed sensor displayed near-Nernstian cationic slope of 55.0 ± 0.8 mV/decade (r2 = 0.999) with a low detection limit of 4.8 × 10−6 mol/L over a wide pH range (3.0–8.5). The electrochemical features of the proposed sensors including electrochemical impedance spectroscopy (EIS) and chronopotentiometry measurements (CP) in the presence of multi-walled carbon nanotubes (MWCNTs) as a solid contact transducer were also investigated. The applications of the proposed sensor for the determination of FLV in different dosage forms with recovery values (98.8%–101.9%) and (97.4%–101.1%), respectively compared with the reference HPLC method with acceptedFandt-student tests values at the 95% confidence level.

scholarly journals Advanced electrochemical platform for determination of cytostatic drug flutamide in various matrices using a boron-doped diamond electrode

2017 ◽  
Vol 251 ◽  
pp. 621-630 ◽  
Author(s):  
Ľubomír Švorc ◽  
Katarína Borovská ◽  
Kristína Cinková ◽  
Dalibor M. Stanković ◽  
Alexandra Planková
Keyword(s):  
Cytostatic Drug ◽  
Boron Doped Diamond ◽  
Diamond Electrode ◽  
Boron Doped ◽  
Boron Doped Diamond Electrode

scholarly journals Sensitive determination of amlodipine besylate using bare/unmodified and DNA-modified screen-printed electrodes in tablets and biological fluids

2017 ◽  
Vol 239 ◽  
pp. 768-775 ◽  
Author(s):  
Mohamed Khairy ◽  
Ahmed A. Khorshed ◽  
Farouk A. Rashwan ◽  
Gamal A. Salah ◽  
Hanaa M. Abdel-Wadood ◽  
...  
Keyword(s):  
Biological Fluids ◽  
Amlodipine Besylate ◽  
Screen Printed Electrodes ◽  
Sensitive Determination ◽  
Screen Printed
Sign in / Sign up

Export Citation Format

Share Document