scholarly journals Oxidative stress biomarkers in Senegal sole, Solea senegalensis, to assess the impact of heavy metal pollution in a Huelva estuary (SW Spain): Seasonal and spatial variation

2012 ◽  
Vol 75 ◽  
pp. 151-162 ◽  
Author(s):  
Milagrosa Oliva ◽  
Juan José Vicente ◽  
Carlos Gravato ◽  
Lucia Guilhermino ◽  
María Dolores Galindo-Riaño
Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3167
Author(s):  
Flavia Buonaurio ◽  
Maria Luisa Astolfi ◽  
Daniela Pigini ◽  
Giovanna Tranfo ◽  
Silvia Canepari ◽  
...  

Urinary concentrations of 16 different exposure biomarkers to metals were determined at the beginning and at the end of a working shift on a group of workers in the metal carpentry industry. Five different oxidative stress biomarkers were also measured, such as the oxidation products of RNA and DNA metabolized and excreted in the urine. The results of workers exposed to metals were compared to those of a control group. The metal concentrations found in these workers were well below the occupational exposure limit values and exceeded the mean concentrations of the same metals in the urine of the control group by a factor of four at maximum. Barium (Ba), mercury (Hg), lead (Pb) and strontium (Sr) were correlated with the RNA oxidative stress biomarker, 8-oxo-7, 8-dihydroguanosine (8-oxoGuo), which was found able to discriminate exposed workers from controls with a high level of specificity and sensitivity. The power of this early diagnostic technique was assessed by means of the ROC curve. Ba, rubidium (Rb), Sr, tellurium (Te), and vanadium (V) were correlated with the level of the protein oxidation biomarker 3-Nitrotyrosine (3-NO2Tyr), and Ba, beryllium (Be), copper (Cu), and Rb with 5-methylcytidine (5-MeCyt), an epigenetic marker of RNA damage. These effect biomarkers can help in identifying those workers that can be defined as “occupationally exposed” even at low exposure levels, and they can provide information about the impact that such doses have on their health.


2018 ◽  
Vol 26 (9) ◽  
pp. 1287-1293 ◽  
Author(s):  
Yuri K. Sinzato ◽  
Estela M. Bevilacqua ◽  
Gustavo T. Volpato ◽  
Rogelio E. Hernandez-Pando ◽  
Marilza V. C. Rudge ◽  
...  

The diabetic syndrome affects pregnancy, contributing to placental functional and structural disruptions and impaired fetal development, with many reports indicating tobacco-associated morbidity and perinatal mortality. In our study, an experimental rat model of diabetes and cigarette smoke exposure in pregnant rats was used to determine the impact of the combination of diabetes and exposure to cigarette smoke during pregnancy on maternal oxidative stress biomarkers and placental and fetal development. Diabetes was induced by streptozotocin, and dams were exposed to cigarette smoke by mainstream smoke generated by a mechanical smoking device and delivered into a chamber. Four groups of dams were studied: nondiabetic (C, control) and diabetic (D) exposed to filtered air and nondiabetic (CS) and diabetic (DS) exposed to cigarette smoke prior to and during pregnancy. Maternal oxidative stress biomarkers, placental morphology, and fetal growth were determined close to term. The combination of diabetes and cigarette smoke resulted in elevated maternal blood glucose levels and increased number of small fetuses. Placentas from the DS group showed increased junctional zone and decreased labyrinthine area. The morphological alterations were characterized by extensive vascular congestion, thickness, and hyalinization of the vascular walls, numerous decidual cells with abundant glycogen, and macrophages with cytoplasmic inclusions of hemosiderin. Additionally, they showed increased glycogen accumulation and junctional zone structural derangement with ectopic giant cells. No alterations were observed in maternal oxidative stress status. Thus, our result suggests that diabetes makes pregnant rats more susceptible to the adverse effects of exposure to cigarette smoke on placental morphometry and fetal growth.


Author(s):  
Navid Omidifar ◽  
Amir Nili-Ahmadabadi ◽  
Amin Nakhostin-Ansari ◽  
Kamran Bagheri Lankarani ◽  
Mohsen Moghadami ◽  
...  

2013 ◽  
Vol 329 ◽  
pp. 56-60
Author(s):  
Lian Qiu Wei

With the rapid development of city economy and increasing of city population , the impact of human activities on the environmental quality of the city is becoming more and more serious. The influence of human activity under the evolution model of city geological environment,has increasingly become the focus of attention. To make the analysis of these data through the concentration of heavy metals in the surface soil of the city, the location of sampling points and heavy metal concentrations of background value, establish a detection model of heavy metal pollution source about city surface soil.


2014 ◽  
Vol 131 ◽  
pp. 134-144 ◽  
Author(s):  
Silvia Espín ◽  
Emma Martínez-López ◽  
Mario León-Ortega ◽  
José Enrique Martínez ◽  
Antonio Juan García-Fernández

2018 ◽  
Vol 26 (1) ◽  
pp. 44-61 ◽  
Author(s):  
Raimondas Šiukšta ◽  
Skaistė Bondzinskaitė ◽  
Violeta Kleizaitė ◽  
Donatas Žvingila ◽  
Ričardas Taraškevičius ◽  
...  

2015 ◽  
Vol 22 (17) ◽  
pp. 13453-13463 ◽  
Author(s):  
Utkarsh A. Reddy ◽  
P. V. Prabhakar ◽  
G. Sankara Rao ◽  
Pasham Rajasekhar Rao ◽  
K. Sandeep ◽  
...  

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