Brominated flame retardants and other organochlorine pollutants in human adipose tissue samples from the Czech Republic

Environmental context. Contamination by hexabromocyclododecanes (HBCDs), a group of brominated flame retardants, is of great concern due to their bioaccumulative nature and toxic implications. HBCD consumption in Japan is the highest among Asian countries and is still growing. In this regard, human exposure to HBCDs is of great concern in Japan. We present here the results of our investigation on Japanese human adipose tissue using LC-MS/MS. HBCDs were detected in all the samples analysed, and were generally higher in men than in women. Abstract. Residue levels of hexabromocyclododecanes (HBCDs) were measured using LC-MS/MS in the Japanese human adipose tissue samples collected during 2003–2004 from Ehime prefecture (n = 26) and Kanto region (n = 9) of Japan. Concentrations of HBCDs (0.85–39 ng g–1 lipid) in the adipose tissue samples were 1–2 orders of magnitude lower than those of organochlorines (OCs). Regional differences between HBCD levels in Ehime prefecture and Kanto region were not significant. No age-dependent accumulation of HBCDs was observed. HBCD levels in men were significantly higher than those in women. Significant positive correlation between polybrominated diphenyl ethers (PBDEs) and HBCDs implies similar routes of exposure to these contaminants for Japanese citizens. α-HBCD was predominant among the three isomers, which is consistent with the other reports on bioaccumulation of α-HBCD in higher trophic animals.

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Brominated flame retardants and phenolic endocrine disrupters in Finnish human adipose tissue

Chemosphere ◽

10.1016/s0045-6535(03)00589-7 ◽

2003 ◽

Vol 53 (9) ◽

pp. 1123-1130 ◽

Cited By ~ 29

Author(s):

Annika Smeds ◽

Pekka Saukko

Keyword(s):

Adipose Tissue ◽

Flame Retardants ◽

Human Adipose Tissue ◽

Brominated Flame Retardants ◽

Endocrine Disrupters

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Corrigendum to “Exposure assessment of French women and their newborn to brominated flame retardants: Determination of tri- to deca-polybromodiphenylethers (PBDE) in maternal adipose tissue, serum, breast milk and cord serum” [Environ. Pollut. 157 (2009) 164–173]

Environmental Pollution ◽

10.1016/j.envpol.2010.06.008 ◽

2010 ◽

Vol 158 (9) ◽

pp. 3012-3013 ◽

Cited By ~ 4

Author(s):

Jean-Philippe Antignac ◽

Ronan Cariou ◽

Daniel Zalko ◽

Alain Berrebi ◽

Jean-Pierre Cravedi ◽

...

Keyword(s):

Adipose Tissue ◽

Breast Milk ◽

Exposure Assessment ◽

Flame Retardants ◽

Brominated Flame Retardants ◽

Cord Serum

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Organohalogen Residues in Human Adipose Autopsy Samples from Six Ontario Municipalities

Journal of AOAC INTERNATIONAL ◽

10.1093/jaoac/71.2.410 ◽

1988 ◽

Vol 71 (2) ◽

pp. 410-414 ◽

Cited By ~ 2

Author(s):

David T Williams ◽

Guy L Lebel ◽

Elizabeth Junkins

Keyword(s):

Adipose Tissue ◽

Great Lakes ◽

Pesticide Residues ◽

Human Adipose Tissue ◽

Frequency Of Occurrence ◽

Tissue Samples ◽

Male And Female

Abstract Human adipose tissue samples obtained during autopsies in 6 Canadian Great Lakes municipalities were analyzed for chlorobenzenes, polychlorobiphenyls, and organohalogen pesticide residues. The frequency of occurrence and the range and mean for 2JJ organohalogen residues are reported for male and female donors in each municipality. Overall mean residue values in females were significantly higher than those in males for hexachlorobenzen;, β-HCH, p,p'- DDE,»,/» -DDD + o,p'-DDT, and p,p'-DDT. The means and ranges of residue values were similar to those reported in previous Canadian surveys.

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