Robotic Prostatectomy for High-risk Prostate Cancer: Translating the Evidence into Lessons for Clinical Practice

2014 ◽  
Vol 65 (5) ◽  
pp. 928-930 ◽  
Author(s):  
Francesco Montorsi
2014 ◽  
Vol 115 (3) ◽  
pp. 419-429 ◽  
Author(s):  
Ketan K. Badani ◽  
Darby J. Thompson ◽  
Gordon Brown ◽  
Daniel Holmes ◽  
Naveen Kella ◽  
...  

2014 ◽  
Vol 13 (1) ◽  
pp. e971
Author(s):  
S.S. Samavedi ◽  
H. Abdul-Muhsin ◽  
P.S.K. Pigilam ◽  
K. Palmer ◽  
G. Ebra ◽  
...  

2020 ◽  
Vol 12 (533) ◽  
pp. eaaz0152 ◽  
Author(s):  
Mitchell G. Lawrence ◽  
Laura H. Porter ◽  
David Clouston ◽  
Declan G. Murphy ◽  
Mark Frydenberg ◽  
...  

Prostate cancer is a common malignancy, but only some tumors are lethal. Accurately identifying these tumors will improve clinical practice and instruct research. Aggressive cancers often have distinctive pathologies, including intraductal carcinoma of the prostate (IDC-P) and ductal adenocarcinoma. Here, we review the importance of these pathologies because they are often overlooked, especially in genomics and preclinical testing. Pathology, genomics, and patient-derived models show that IDC-P and ductal adenocarcinoma accompany multiple markers of poor prognosis. Consequently, “knowing what is growing” will help translate preclinical research to pinpoint and treat high-risk prostate cancer in the clinic.


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