Can transcranial direct current stimulation really optimize gait recovery in children with cerebral palsy or is the effect determined by some type of motor training?

2016 ◽  
Vol 49 ◽  
pp. 35
Medicine ◽  
2021 ◽  
Vol 100 (49) ◽  
pp. e27962
Author(s):  
Xiao-Liang Chen ◽  
Li-Ping Yu ◽  
Ying Zhu ◽  
Tie-Yan Wang ◽  
Jing Han ◽  
...  

2020 ◽  
Vol 83 (7) ◽  
pp. 418-431
Author(s):  
Anna Patricia Nicole Diego ◽  
Ada WS Leung

Introduction The functional abilities of children with cerebral palsy are often compromised because of limited motor function. Transcranial direct current stimulation is a neuromodulation tool used as an adjunct to other therapeutic modalities to improve gross motor function. This review aimed to examine the quality of evidence and the effectiveness of transcranial direct current stimulation for improving gross motor function in children with cerebral palsy. Method A systematic review was conducted, and eligible studies were critically appraised for methodological quality. Randomised controlled trials were selected to undergo meta-analysis for assessing the effectiveness of transcranial direct current stimulation on clinical outcomes. Results Eight studies, including seven randomised controlled trials, fitted the inclusion criteria. All the randomised controlled trials were rated ‘moderate’ quality based on the grading of recommendations assessment, development and evaluation (GRADE) system. Using meta-analysis, only cadence, an outcome measure of gait variables, demonstrated efficacy of intervention, mean difference 16.57 (10.88, 22.25); I2 = 0%, P = 0.83. Other gross motor and functional outcomes had either inconsistent mean difference or high heterogeneity. Conclusion Overall, the effectiveness of transcranial direct current stimulation as a treatment in children with cerebral palsy remains unclear, and the findings should be interpreted with caution. The quality of evidence was mostly moderate, and more vigorous research incorporating functional outcomes should be conducted to guide clinical practice.


2020 ◽  
Vol 10 (7) ◽  
pp. 2616
Author(s):  
Małgorzata Smoter ◽  
Beata Jędrzejczyk-Góral ◽  
Aiguo Chen ◽  
Bogdan Ciszek ◽  
Zofia Ignasiak

Background: The aim of this study was to investigate the influence of transcranial direct current stimulation (tDCS) on the biceps brachii and flexor carpi radialis stiffness in children with cerebral palsy (CP). The authors also aimed to verify the relationship between spasticity and muscle stiffness. Methods: Twelve children with CP (mean ± SD; age, 8 ± 1.3 years; height, 118.7 ± 4.1 cm; weight, 23.0 ± 2.2 kg) were involved in the study. Muscle stiffness was estimated using a MyotonPRO device in a MultiScan pattern of five measurements. Simultaneously, the tDCS stimulation was performed. Spasticity was assessed by a neurologist using the Ashworth Scale. Results: Stiffness of the flexor carpi radialis muscle decreased significantly after tDCS therapy (p = 0.04). There was no significant change in stiffness of the biceps brachii. For all participants, the Spearman rank correlation showed statistically significant and positive relationships between muscle stiffness and the Ashworth Scale (p = 0.04). Conclusions: Transcranial direct current stimulation has a decreasing effect on stiffness and spasticity of the flexor carpi radialis in children with CP. The MyotonPRO device provides objective data and correlates with spasticity measurements.


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