Mo1398 Single Operator PerOral Pancreatoscopy for Main Duct Intraductal Papillary Mucinous Neoplasm Is Highly Specific but Has Poor Sensitivity

2015 ◽  
Vol 81 (5) ◽  
pp. AB406
Author(s):  
Aaron J. Small ◽  
Gregory Lutzak ◽  
Seng-Ian Gan ◽  
Shayan Irani ◽  
Michael Gluck ◽  
...  
Keyword(s):  
Intraductal Papillary Mucinous Neoplasm ◽  
Main Duct ◽  
Mucinous Neoplasm ◽  
Single Operator

scholarly journals Tu1423 DIGITAL PANCREATOSCOPY IN THE EVALUATION OF MAIN DUCT INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM: A MULTI-CENTER STUDY

2018 ◽  
Vol 87 (6) ◽  
pp. AB591-AB592
Author(s):  
Arvind J. Trindade ◽  
Petros C. Benias ◽  
Praneet Korrapati ◽  
Benjamin Tharian ◽  
Sumant Inamdar ◽  
...  
Keyword(s):  
Intraductal Papillary Mucinous Neoplasm ◽  
Main Duct ◽  
Mucinous Neoplasm ◽  
Multi Center Study ◽  
Center Study

scholarly journals Biliary tract intraductal papillary mucinous neoplasm: single-operator cholangioscopy and clearance of mucin obstruction

Endoscopy ◽  
2016 ◽  
Vol 48 (S 01) ◽  
pp. E150-E151
Author(s):  
Tomazo Franzini ◽  
Renata Moura ◽  
Silvia de Lima ◽  
Gustavo Rodela ◽  
Frederico Teixeira ◽  
...  
Keyword(s):  
Biliary Tract ◽  
Intraductal Papillary Mucinous Neoplasm ◽  
Mucinous Neoplasm ◽  
Single Operator

Suggestion of new nomogram including inflammatory marker for predicting invasive carcinoma in intraductal papillary mucinous neoplasm of the pancreas.

2019 ◽  
Vol 37 (4_suppl) ◽  
pp. 204-204
Author(s):  
In Woong Han
Keyword(s):  
Risk Factors ◽  
Factor Analysis ◽  
Risk Factor ◽  
Intraductal Papillary Mucinous Neoplasm ◽  
Inflammatory Markers ◽  
Invasive Carcinoma ◽  
Main Duct ◽  
Solid Portion ◽  
Mucinous Neoplasm ◽  
Invasive Ipmn

204 Background: Previous studies have analyzed that inflammatory markers, such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and advanced lung cancer inflammation index (ALI), associated with the presence of invasive carcinoma in patients with intraductal papillary mucinous neoplasm (IPMN). This study aimed to evaluate the correlation between the inflammatory markers and the invasive carcinoma in IPMN and propose a nomogram including inflammatory markers for predicting invasive IPMN. Methods: From 1995 to 2016, total 468 patients who underwent surgical resection at four institutions for histologically confirmed IPMN and the data were reviewed retrospectively. The patients with history of pancreatitis, other malignancies and without CA19-9 data or lymphocyte counts were excluded, the study cohort consisted of 365 patients. Variables with P < 0.05 in risk factor analysis were included in the nomogram. Results: Of 365 patients, 98 (26.8%) patients had invasive IPMN. In univariate analysis, high body mass index (BMI) ( P = 0.037), pre-operative bilirubin level ( P = 0.001), CA19-9 ( P < 0.001), NLR ( P = 0.019), PLR ( P = 0.002), ALI ( P = 0.001), main duct type (P < 0.001), the presence of solid portion ( P < 0.001) and tumor size (P = 0.086) were identified as risk factors for invasive IPMN. In multivariate analysis, pre-operative bilirubin level (P = 0.003), CA19-9 (P = 0.002), main duct type (P = 0.034) and the presence of solid portion (P < 0.001) were independent predictive markers for invasive IPMN. The nomogram was developed including all factors of risk factor analysis. Conclusions: The inflammatory markers were the risk factors for the presence of IPMN-associated invasive carcinoma. This nomogram may be useful in identifying patients with IPMN at risk of malignancy and for selecting which patients should undergo surgery. Further validation studies are needed to assess the predictive ability of nomogram including inflammatory markers.

scholarly journals Main-duct intraductal papillary mucinous neoplasm of the pancreas: a case report

2012 ◽  
Vol 6 (4) ◽  
pp. 127-134
Author(s):  
Natalia Manetti ◽  
Clara Faini ◽  
Francesca Bucciero ◽  
Giulia Razzolini ◽  
Maria Marsico ◽  
...  
Keyword(s):  
Intraductal Papillary Mucinous Neoplasm ◽  
Tumour Size ◽  
Mucinous Cystic Neoplasm ◽  
Cystic Mass ◽  
Cystic Neoplasm ◽  
Main Duct ◽  
Branch Duct ◽  
Recurrent Acute Pancreatitis ◽  
Mucinous Neoplasm ◽  
Wirsung Duct

Three distinct entities among non-inflammatory cystic lesions of the pancreas have been defined: intraductal papillary mucinous neoplasm (IPMN), serous cystic neoplasm (SCN) and mucinous cystic neoplasm (MCN). IPMN is characterized by intraductal papillary growth and thick mucus secretion: its incidence has dramatically increased since its initial description. These lesions probably can progress towards invasive carcinoma. IPMNs are symptomatic in most cases: the typical presentation is a recurrent acute pancreatitis, without evident cause, of low or moderate severity. The diagnosis is usually based upon the imaging (CT/cholangio-MRI) demonstrating a pancreatic cystic mass, involving a dilated main duct, eventually associated to some filling defects, or a normal Wirsung duct communicating with the cyst lesion. Surgical treatment is generally indicated for main duct IPMN and branch duct IPMN with suspected malignancy (tumour size ≥ 30 mm, mural nodules, dilated main pancreatic duct, or positive cytology) or prominent symptoms. Herein we present a case of IPMN of the main duct which occurred with abdominal and back pain associated with weight loss. After the diagnosis, she successfully underwent surgery and is now in a follow-up program.

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